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View Structure Prediction Details

Protein: PUS1_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 544 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PUS1_YEAST.

Description E-value Query
Range
Subject
Range
PUS1_YEAST - tRNA pseudouridine synthase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PUS1 PE=1 ...
gi|151942589 - gi|151942589|gb|EDN60935.1| tRNA-pseudouridine synthase [Saccharomyces cerevisiae YJM789]
PUS1 - tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA...
gi|190407751 - gi|190407751|gb|EDV11016.1| tRNA pseudouridine synthase [Saccharomyces cerevisiae RM11-1a]
0.0 [1..544] [1..544]
gi|25518568, gi|... - gi|9558589|gb|AAF88152.1|AC026234_3 Contains similarity to a pseudouridine synthase 1 from Homo sapi...
2.0E-96 [30..524] [8..547]
pus1 - tRNA pseudouridylate synthase Lsp1
PUS1_SCHPO - tRNA pseudouridine synthase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pus1 PE=1 SV...
2.0E-87 [44..506] [11..531]
TRUA_SALCH - tRNA pseudouridine synthase A OS=Salmonella choleraesuis GN=truA PE=3 SV=1
TRUA_SALTI - tRNA pseudouridine synthase A OS=Salmonella typhi GN=truA PE=3 SV=1
TRUA_SALA4 - tRNA pseudouridine synthase A OS=Salmonella agona (strain SL483) GN=truA PE=3 SV=1
TRUA_SALPK - tRNA pseudouridine synthase A OS=Salmonella paratyphi A (strain AKU_12601) GN=truA PE=3 SV=1
TRUA_SALDC - tRNA pseudouridine synthase A OS=Salmonella dublin (strain CT_02021853) GN=truA PE=3 SV=1
gi|200388490, gi... - gi|200388490|ref|ZP_03215102.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
TRUA_SALNS - tRNA pseudouridine synthase A OS=Salmonella newport (strain SL254) GN=truA PE=3 SV=1
TRUA_SALHS - tRNA pseudouridine synthase A OS=Salmonella heidelberg (strain SL476) GN=truA PE=3 SV=1
TRUA_SALPA - tRNA pseudouridine synthase A OS=Salmonella paratyphi A GN=truA PE=3 SV=1
gi|194471784, gi... - gi|194471784|ref|ZP_03077768.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
TRUA_SALPB - tRNA pseudouridine synthase A OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=truA PE=3 S...
TRUA_SALSV - tRNA pseudouridine synthase A OS=Salmonella schwarzengrund (strain CVM19633) GN=truA PE=3 SV=1
gi|238912353 - gi|238912353|ref|ZP_04656190.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
gi|29136636, gi|... - gi|29141011|ref|NP_804353.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica sero...
gi|197289616, gi... - gi|197289616|gb|EDY28979.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica serov...
gi|16761293 - gi|16761293|ref|NP_456910.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica sero...
gi|168242494, gi... - gi|205338670|gb|EDZ25434.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica serov...
gi|168465920, gi... - gi|195631471|gb|EDX50031.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica serov...
TRUA_SALTI - tRNA pseudouridine synthase A OS=Salmonella typhi GN=truA PE=3 SV=1
gi|205344778, gi... - gi|205344778|gb|EDZ31542.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica serov...
gi|205325206, gi... - gi|205325206|gb|EDZ13045.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica serov...
gi|205335762, gi... - gi|205335762|gb|EDZ22526.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica serov...
gi|214002040 - gi|214002040|ref|ZP_03412775.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
TRUA_SALPC - tRNA pseudouridine synthase A OS=Salmonella paratyphi C (strain RKS4594) GN=truA PE=3 SV=1
gi|213161334 - gi|213161334|ref|ZP_03347044.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
gi|213426977 - gi|213426977|ref|ZP_03359727.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
TRUA_SALCH - tRNA pseudouridine synthase A OS=Salmonella choleraesuis GN=truA PE=3 SV=1
gi|213646800 - gi|213646800|ref|ZP_03376853.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
TRUA_SALPB - tRNA pseudouridine synthase A OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=truA PE=3 S...
gi|213852689 - gi|213852689|ref|ZP_03382221.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
gi|204929209, gi... - gi|204929209|ref|ZP_03220352.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
TRUA_SALG2 - tRNA pseudouridine synthase A OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=truA PE=3 SV=...
TRUA_SALCH - tRNA pseudouridine synthase A OS=Salmonella choleraesuis (strain SC-B67) GN=truA PE=3 SV=1
TRUA_SALEP - tRNA pseudouridine synthase A OS=Salmonella enteritidis PT4 (strain P125109) GN=truA PE=3 SV=1
TRUA_SALPA - tRNA pseudouridine synthase A OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=truA PE=3 SV=...
gi|213022210 - gi|213022210|ref|ZP_03336657.1| tRNA pseudouridine synthase A [Salmonella enterica subsp. enterica s...
1.0E-73 [71..305] [6..236]
gi|262167166|ref... - tRNA pseudouridine synthase A [Vibrio cholerae RC27]
gi|194535182, gi... - gi|75823320|ref|ZP_00752830.1| COG0101: Pseudouridylate synthase [Vibrio cholerae RC385], gi|2542235...
gi|254848129, gi... - gi|75829810|ref|ZP_00759102.1| COG0101: Pseudouridylate synthase [Vibrio cholerae MO10], gi|25484812...
gi|262151270|ref... - tRNA pseudouridine synthase A [Vibrio cholerae INDRE 91/1]
TRUA_VIBCM - tRNA pseudouridine synthase A OS=Vibrio cholerae serotype O1 (strain M66-2) GN=truA PE=3 SV=1
gi|229357625, gi... - gi|229505402|ref|ZP_04394912.1| tRNA pseudouridine synthase A [Vibrio cholerae BX 330286], gi|229357...
gi|121587328, gi... - gi|121587328|ref|ZP_01677099.1| tRNA pseudouridine synthase A [Vibrio cholerae 2740-80], gi|12154841...
gi|229510928, gi... - gi|229510928|ref|ZP_04400407.1| tRNA pseudouridine synthase A [Vibrio cholerae B33], gi|229350893|gb...
gi|124118635, gi... - gi|153222761|ref|ZP_01953420.1| tRNA pseudouridine synthase A [Vibrio cholerae MAK 757], gi|12411863...
gi|229344764, gi... - gi|229518049|ref|ZP_04407493.1| tRNA pseudouridine synthase A [Vibrio cholerae RC9], gi|229344764|gb...
gi|126509619, gi... - gi|153819838|ref|ZP_01972505.1| tRNA pseudouridine synthase A [Vibrio cholerae NCTC 8457], gi|126509...
gi|229529907, gi... - gi|229529907|ref|ZP_04419297.1| tRNA pseudouridine synthase A [Vibrio cholerae 12129(1)], gi|2293336...
gi|229371076, gi... - gi|229608421|ref|YP_002879069.1| tRNA pseudouridine synthase A [Vibrio cholerae MJ-1236], gi|2293710...
gi|183179415, gi... - gi|183179415|ref|ZP_02957626.1| tRNA pseudouridine synthase A [Vibrio cholerae MZO-3], gi|183012826|...
gi|255744781|ref... - tRNA pseudouridine synthase A [Vibrio cholera CIRS 101]
gi|262190865|ref... - tRNA pseudouridine synthase A [Vibrio cholerae CT 5369-93]
TRUA_VIBC3 - tRNA pseudouridine synthase A OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 39...
TRUA_VIBCH - tRNA pseudouridine synthase A OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N1696...
TRUA_VIBCH - tRNA pseudouridine synthase A OS=Vibrio cholerae GN=truA PE=3 SV=1
1.0E-73 [76..305] [2..227]
gi|293415611|ref... - tRNA pseudouridine synthase A [Escherichia coli B185]
TRUA_ECOL6 - tRNA pseudouridine synthase A OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=truA...
gi|209764792, gi... - pir||C85873 pseudouridylate synthase I [imported] - Escherichia coli (strain O157:H7, substrain EDL...
gi|291283559|ref... - tRNA pseudouridine synthase A [Escherichia coli O55:H7 str. CB9615]
gi|12516677, gi|... - gi|15802865|ref|NP_288892.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 EDL933], gi|125...
gi|189362830, gi... - gi|189362830|gb|EDU81249.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4486], gi...
TRUA_ECO57 - tRNA pseudouridine synthase A OS=Escherichia coli O157:H7 GN=truA PE=3 SV=1
gi|168761239, gi... - gi|189368293|gb|EDU86709.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4501], gi...
TRUA_ECOL6 - tRNA pseudouridine synthase A OS=Escherichia coli O6 GN=truA PE=3 SV=1
gi|189357607, gi... - gi|189357607|gb|EDU76026.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4401], gi...
gi|293410675|ref... - tRNA pseudouridine synthase A [Escherichia coli B354]
gi|261223227|ref... - tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. FRIK2000]
gi|188017261, gi... - gi|188017261|gb|EDU55383.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4113], gi...
gi|168798493, gi... - gi|189378874|gb|EDU97290.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC508], gi|...
gi|168787230, gi... - gi|189372810|gb|EDU91226.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC869], gi|...
gi|168780178, gi... - gi|189001906|gb|EDU70892.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4076], gi...
gi|187771144, gi... - gi|187771144|gb|EDU34988.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4196], gi...
gi|293405784|ref... - tRNA pseudouridine synthase A [Escherichia coli FVEC1412]
gi|13362672, gi|... - gi|15832456|ref|NP_311229.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. Sakai], gi...
gi|261259223|ref... - tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. FRIK966]
TRUA_ECOLU - tRNA pseudouridine synthase A OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=truA PE=3 S...
TRUA_ECO7I - tRNA pseudouridine synthase A OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=truA PE=3 SV=1
gi|208811862, gi... - gi|208811862|ref|ZP_03253191.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4045]...
gi|208727696, gi... - gi|208807895|ref|ZP_03250232.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4206]...
gi|195935697 - gi|195935697|ref|ZP_03081079.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4024]
TRUA_ECOSM - tRNA pseudouridine synthase A OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=truA PE=3 SV=1
TRUA_ECO55 - tRNA pseudouridine synthase A OS=Escherichia coli (strain 55989 / EAEC) GN=truA PE=3 SV=1
gi|217319539, gi... - gi|217327172|ref|ZP_03443255.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. TW14588...
TRUA_ECO5E - tRNA pseudouridine synthase A OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=truA PE=3 SV=1
gi|208741667, gi... - gi|208821544|ref|ZP_03261864.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4042]...
gi|293446655|ref... - tRNA pseudouridine synthase A [Escherichia coli B088]
gi|254794211, gi... - gi|254794211|ref|YP_003079048.1| tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. TW1435...
gi|227887378, gi... - gi|227887378|ref|ZP_04005183.1| tRNA pseudouridine synthase A [Escherichia coli 83972], gi|227835728...
TRUA_SHIDS - tRNA pseudouridine synthase A OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=truA PE=3 SV=1
8.0E-73 [72..305] [7..236]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEENLRPAY DDQVNEDVYK RGAQSKLTKA RKADFDDEKD KKKDNDKHID KRPKSGPRLD  60
   61 ENGN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [65-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPKEPRLPK RKVAVMVGYC GTGYHGMQYN PPNPTIESAL FKAFVEAGAI SKDNSNDLKK  60
   61 NGFMRAARTD KGVHAGGNLI SLKMIIEDPD IKQKINEKLP EGIRVWDIER VNKAFDCRKM 120
  121 CSSRWYEYLL PTYSLIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.68867
Match: 1dj0A_
Description: Pseudouridine synthase I
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [202-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKPGSILYRD IEESKTELPG VLDEDLESKE FWEEFKKDAN EKFSTEEIEA ILAYVPPARD  60
   61 EFDINEELYQ KVKKYKQLEN AHRRRYRISA AKLAKFRAST SQYLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 100.68867
Match: 1dj0A_
Description: Pseudouridine synthase I
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [307-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHNFHNFTLG KDFKEPSAIR FMKDIKVSDP FVIGDAQTEW ISIKIHGQSF MLHQIRKMVS  60
   61 MATLITRCGC PVERISQAYG QQKINIPKAP ALGLLLEAPV FEGYNKRLEQ FGYKAIDFSK 120
  121 YQDEVDKFKM KHIYDKIYKE EVDENVFNAF FSYIDSFNKV TGAQGEETAD KSGPAVQKSI 180
  181 FEFLTAKGIP GLTDAPESNK KIKQRKRMEE EEAASKKAEI SSTTQSNEPE VQPEAAAN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
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