YRC Public Data Repository - Protein Structure Prediction

Protein:	EG10823
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	353 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG10823.

Description	E-value	Query Range	Subject Range
gi\|66270756 - gi\|66270756\|gb\|AAY43691.1\| RecA/GFP fusion protein [Cloning vector pSJS1472]	417.0	[0..1]	[353..1]
RECA_SALTI - Protein recA OS=Salmonella typhi GN=recA PE=3 SV=2 RECA_SALTY - Protein RecA OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=recA PE=1 SV=2 gi\|29143089, gi\|... - gi\|29143089\|ref\|NP_806431.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str. T... RECA_SALCH - Protein RecA OS=Salmonella choleraesuis (strain SC-B67) GN=recA PE=3 SV=3 RECA_SALTY - Protein recA OS=Salmonella typhimurium GN=recA PE=3 SV=2 RECA_SALCH - Protein recA OS=Salmonella choleraesuis GN=recA PE=3 SV=3 RECA_SALTI - Protein RecA OS=Salmonella typhi GN=recA PE=3 SV=2 gi\|16761605 - gi\|16761605\|ref\|NP_457222.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str. C... gi\|168464049, gi... - gi\|195633723\|gb\|EDX52137.1\| protein RecA [Salmonella enterica subsp. enterica serovar Newport str. S... gi\|168820488, gi... - gi\|205342838\|gb\|EDZ29602.1\| protein RecA [Salmonella enterica subsp. enterica serovar Weltevreden st... RECA_SALNS - Protein RecA OS=Salmonella newport (strain SL254) GN=recA PE=3 SV=1 RECA_SALHS - Protein RecA OS=Salmonella heidelberg (strain SL476) GN=recA PE=3 SV=1 gi\|238909595 - gi\|238909595\|ref\|ZP_04653432.1\| recombinase A [Salmonella enterica subsp. enterica serovar Tennessee... gi\|205327960, gi... - gi\|205327960\|gb\|EDZ14724.1\| protein RecA [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- s... gi\|168235857, gi... - gi\|197290652\|gb\|EDY30006.1\| protein RecA [Salmonella enterica subsp. enterica serovar Schwarzengrund... gi\|205335992, gi... - gi\|205335992\|gb\|EDZ22756.1\| protein RecA [Salmonella enterica subsp. enterica serovar Heidelberg str... gi\|168262060, gi... - gi\|205349184\|gb\|EDZ35815.1\| protein RecA [Salmonella enterica subsp. enterica serovar Hadar str. RI_... lcl\|NC_016856.1_... - [gene=recA] [protein=recombinase A] [protein_id=YP_005238927.1] [location=complement(2995089..299615... gi\|213648097 - gi\|213648097\|ref\|ZP_03378150.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str... gi\|214000004 - gi\|214000004\|ref\|ZP_03410739.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str... RECA_SALPC - Protein RecA OS=Salmonella paratyphi C (strain RKS4594) GN=recA PE=3 SV=1 gi\|213028317 - gi\|213028317\|ref\|ZP_03342764.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str... gi\|109453384, gi... - gi\|109453400\|gb\|ABG34180.1\| RecA [Salmonella enterica subsp. enterica], gi\|109453398\|gb\|ABG34179.1\| ... gi\|213051937 - gi\|213051937\|ref\|ZP_03344815.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213426123 - gi\|213426123\|ref\|ZP_03358873.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str... RECA_SALPB - Protein RecA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=recA PE=3 SV=1 gi\|213579899 - gi\|213579899\|ref\|ZP_03361725.1\| recombinase A [Salmonella enterica subsp. enterica serovar Typhi str... RECA_SALTY - Protein RecA OS=Salmonella typhimurium GN=recA PE=3 SV=2 RECA_SALPB - Protein recA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=recA PE=3 SV=1 gi\|199603797, gi... - gi\|200386699\|ref\|ZP_03213311.1\| protein RecA [Salmonella enterica subsp. enterica serovar Virchow st... RECA_SALCH - Protein RecA OS=Salmonella choleraesuis GN=recA PE=3 SV=3 gi\|204928070, gi... - gi\|204928070\|ref\|ZP_03219270.1\| protein RecA [Salmonella enterica subsp. enterica serovar Javiana st... RECA_SALG2 - Protein RecA OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=recA PE=3 SV=1 RECA_SALEP - Protein RecA OS=Salmonella enteritidis PT4 (strain P125109) GN=recA PE=3 SV=1 RECA_SALSV - Protein RecA OS=Salmonella schwarzengrund (strain CVM19633) GN=recA PE=3 SV=1 RECA_SALA4 - Protein RecA OS=Salmonella agona (strain SL483) GN=recA PE=3 SV=1 gi\|197241862, gi... - gi\|197263607\|ref\|ZP_03163681.1\| protein RecA [Salmonella enterica subsp. enterica serovar Saintpaul ... RECA_SALDC - Protein RecA OS=Salmonella dublin (strain CT_02021853) GN=recA PE=3 SV=1	405.0	[0..1]	[353..1]
gi\|55670292, gi\|... - gi\|58177454\|pdb\|1XMV\|A Chain A, "e. Coli Reca In Complex With Mgadp", gi\|58177451\|pdb\|1XMS\|A Chain A...	405.0	[0..1]	[353..4]
gi\|227834504, gi... - gi\|227888235\|ref\|ZP_04006040.1\| recombination protein A [Escherichia coli 83972], gi\|227834504\|gb\|EE... gi\|226899721, gi... - gi\|237706681\|ref\|ZP_04537162.1\| recombinase A [Escherichia sp. 3_2_53FAA], gi\|226899721\|gb\|EEH85980.... gi\|254037738, gi... - gi\|254037738\|ref\|ZP_04871796.1\| recombinase A [Escherichia sp. 1_1_43], gi\|226839362\|gb\|EEH71383.1\| ... gi\|24053114, gi\|... - ref\|NP_708507.1\| RecA protein [Shigella flexneri 2a str. 301], gb\|AAN44214.1\| RecA protein [Shigell... gi\|115514054, gi... - gi\|117624930\|ref\|YP_853918.1\| recombinase A [Escherichia coli APEC O1], gi\|115514054\|gb\|ABJ02129.1\| ...	405.0	[0..1]	[353..6]
RECA_SHISO - Protein RecA OS=Shigella sonnei GN=recA PE=3 SV=3	405.0	[0..1]	[353..1]
RECA_SALPK - Protein RecA OS=Salmonella paratyphi A (strain AKU_12601) GN=recA PE=3 SV=1 RECA_SALPA - Protein RecA OS=Salmonella paratyphi A GN=recA PE=3 SV=3 RECA_SALPA - Protein RecA OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=recA PE=3 SV=3	404.0	[0..1]	[353..1]
gi\|15803214, gi\|... - gi\|15803214\|ref\|NP_289246.1\| recombinase A [Escherichia coli O157:H7 EDL933], gi\|12517139\|gb\|AAG5780... gi\|25300497 - gi\|25300497\|pir\|\|H85917 hypothetical protein recA [imported] - Escherichia coli (strain O157:H7, su...	403.0	[0..1]	[353..1]
gi\|9654971, gi\|1... - gi\|9654971\|gb\|AAF93711.1\| recA protein [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|15640565\|r... gi\|11356058 - gi\|11356058\|pir\|\|E82310 recA protein VC0543 [imported] - Vibrio cholerae (strain N16961 serogroup O1...	402.0	[0..3]	[353..59]
RECA_VIBPA - Protein RecA OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=recA PE=3 SV=1 RECA_VIBPA - Protein RecA OS=Vibrio parahaemolyticus GN=recA PE=3 SV=1	400.0	[0..3]	[348..1]

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Predicted Domain #1

Region A:
Residues: [1-353]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIDENKQKA LAAALGQIEK QFGKGSIMRL GEDRSMDVET ISTGSLSLDI ALGAGGLPMG  60
   61 RIVEIYGPES SGKTTLTLQV IAAAQREGKT CAFIDAEHAL DPIYARKLGV DIDNLLCSQP 120
  121 DTGEQALEIC DALARSGAVD VIVVDSVAAL TPKAEIEGEI GDSHMGLAAR MMSQAMRKLA 180
  181 GNLKQSNTLL IFINQIRMKI GVMFGNPETT TGGNALKFYA SVRLDIRRIG AVKEGENVVG 240
  241 SETRVKVVKN KIAAPFKQAE FQILYGEGIN FYGELVDLGV KEKLIEKAGA WYSYKGEKIG 300
  301 QGKANATAWL KDNPETAKEI EKKVRELLLS NPNSTPDFSV DDSEGVAETN EDF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	114.0
Match:	1u94A
Description:	Crystal Structure of E. Coli RecA in a Compressed Helical Filament Form 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphatase activity	1.5002869400376	bayes_pls_golite062009
pyrophosphatase activity	1.49611313354225	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.47468810672455	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.47371190790284	bayes_pls_golite062009
binding	1.41264401383678	bayes_pls_golite062009
hydrolase activity	1.29419296935491	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
ATPase activity	0.844502974582959	bayes_pls_golite062009
DNA-dependent ATPase activity	0.510757066819002	bayes_pls_golite062009
helicase activity	0.51056840156051	bayes_pls_golite062009
purine nucleotide binding	0.360529478474946	bayes_pls_golite062009
nucleotide binding	0.354857598792381	bayes_pls_golite062009
purine ribonucleotide binding	0.35235724478784	bayes_pls_golite062009
ribonucleotide binding	0.352298062690593	bayes_pls_golite062009
protein binding	0.231495635179652	bayes_pls_golite062009
nucleic acid binding	0.216266069700019	bayes_pls_golite062009
DNA helicase activity	0.148854929640752	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: