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View Structure Prediction Details

Protein: GCS2_ARATH
Organism: Arabidopsis thaliana
Length: 789 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCS2_ARATH.

Description E-value Query
Range
Subject
Range
gi|13398928 - gi|13398928|emb|CAC34725.1| alpha-glucosidase 1 [Arabidopsis thaliana]
910.0 [0..13] [789..76]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGLSPSGDI KPLLDDESQR PRVITPFPSP KLTDLSMFQG EHKESLYWGT YRPQMYFGVR  60
   61 ARTPKSLVAG LMWLVMKDGK PVMRHFCENS NDLKSFGWKE HNGRDFGRQE LFEQNMVLET 120
  121 SFVKSEEGSL GYGGDWSIRI NVQNMLNDDE VKRSTHLFFY LADEGCNGVN LGKDVLRLKE 180
  181 SSVLASGSRQ DVGNWQMHLK SQN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.969
Match: 1e17A
Description: Afx (Foxo4)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.29529712379515 bayes_pls_golite062009
nucleic acid binding 3.11707801662554 bayes_pls_golite062009
DNA binding 3.03907941828864 bayes_pls_golite062009
binding 2.74878522224363 bayes_pls_golite062009
transcription factor activity 2.40166432224452 bayes_pls_golite062009
sequence-specific DNA binding 1.06761237121162 bayes_pls_golite062009
transcription activator activity 0.942242507427478 bayes_pls_golite062009
transcription repressor activity 0.797794853673959 bayes_pls_golite062009
protein binding 0.626618806841206 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.333159018967324 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [204-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLETHYCGFK TPDIVNLSGL VQQNLTAQEE KSGLLQLSDS SEDSSNIYVF QISTTNQSTI  60
   61 DIAFVSGIKE ETSNMENRIM SLTGLPLSSL LEEKHIAFNA KFNECFNLSD KLDPETLVVG 120
  121 KAAIGNMLGG IGYFYGQSKI HFPKSPLAKS ED

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [356-789]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFLLYWPAEL YTAVPSRPRF PRGFLWDEGF HQLLIWRWDV HITLEIVGNW LDLMNIDGWI  60
   61 PREQVLGAEA LSKIPKQYVV QFPSNGNPPT LLLVIRDLIN GIRTEKFNEA DRDKILSFLD 120
  121 RAFVRLDAWF KWFNTSQIGK EKGSYYWHGR DNITNRELNP QSLSSGLDDY PRASHPNEDE 180
  181 RHVDLRCWMY LAADSMNSIQ EFMGKNDILV TEDYSSIAKL LSDFTLLNQM HYDKDHGAYL 240
  241 DFGNHTEEVR LVWKEVIHED GHLSRELVRE TYGKPELRLV PHIGYVSFFP FMFRIIPADS 300
  301 SILDKQLDLI SNGNIVWSDY GLLSLAKTSS LYMKYNSEHQ APYWRGAIWM NMNYMILSSL 360
  361 HHYSTVDGPY NSKARTIYEE LRSNLIRNVV RNYDQTGIIW EHYDQTKGTG EGARVFTGWS 420
  421 ALILLIMSEE YPLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.39794
Match: 2jf4A
Description: No description for 2jf4A was found.

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 3.49882811932206 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.13521240810366 bayes_pls_golite062009
catalytic activity 1.16285856935495 bayes_pls_golite062009
binding 1.06330183651166 bayes_pls_golite062009
trehalase activity 0.389375574251869 bayes_pls_golite062009
protein binding 0.18984948020481 bayes_pls_golite062009
alpha,alpha-trehalase activity 0.17719034423607 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle