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View Structure Prediction Details

Protein: URIC_ARATH
Organism: Arabidopsis thaliana
Length: 309 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for URIC_ARATH.

Description E-value Query
Range
Subject
Range
URIC_ARATH - Uricase - Arabidopsis thaliana (Mouse-ear cress)
476.0 [0..1] [309..1]

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Predicted Domain #1
Region A:
Residues: [1-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQEADGIRL DQRHGKARVR VGRVWRHAHD GSHHFVEWNV SISLLSHCLS SYRLDDNSDI  60
   61 VATDTIKNTV YVKAKECGDR LSVEEFAILI GKHFCSFYPQ VFTAIVNIIE KPWERVSIDG 120
  121 KPHLHGFKLG SENHTTEARV EKSGALNLTS GIGGLALLKT TQSGFERFVR DKYTILPETR 180
  181 ERMLATEVNA SWRYSYESVA SIPTKGLYFS EKFMDVKKVL MDTFFGPPET GVYSPSVQRT 240
  241 LYLMGSAVLK RFADVSSIHL KMPNIHFLPV NLSTKENPSM VKFKDDVYLP TDEPHGSIEA 300
  301 TLSRITSKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 121.0
Match: 1r4sA
Description: URATE OXIDASE FROM ASPERGILLUS FLAVUS COMPLEXED WITH ITS INHIBITOR 9-METHYL URIC ACID
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
urate oxidase activity 4.98056582061231 bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor 4.31732265940848 bayes_pls_golite062009
GTP cyclohydrolase I activity 3.71208106424087 bayes_pls_golite062009
catalytic activity 2.20788162511962 bayes_pls_golite062009
GTP cyclohydrolase activity 1.89570925022701 bayes_pls_golite062009
cyclohydrolase activity 1.8212867268343 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1.73101699306211 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.974891318710762 bayes_pls_golite062009
binding 0.876314139116894 bayes_pls_golite062009
dihydroneopterin aldolase activity 0.803156673865251 bayes_pls_golite062009
6-pyruvoyltetrahydropterin synthase activity 0.756899305060565 bayes_pls_golite062009
hydrolase activity 0.734877553662152 bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors 0.448906913739211 bayes_pls_golite062009
oxidoreductase activity 0.0310611456658956 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle