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View Structure Prediction Details

Protein: CCR4A_ARATH
Organism: Arabidopsis thaliana
Length: 602 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCR4A_ARATH.

Description E-value Query
Range
Subject
Range
gi|6735373, gi|1... - gi|6735373|emb|CAB68194.1| putative protein [Arabidopsis thaliana], pir||T45676 hypothetical protein...
512.0 [0..1] [602..1]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSVIRVHLP SEIPIVGCEL TPYVLLRRPD KTPSTDDVPE SAPLEGHFLK YRWFRVQSDK  60
   61 KVAICSVHPS ETATLQCLGC LKSKVPVAKS YHCSTKCFSD AWQHHRVLHE RAAS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.6
Match: 2d8qA
Description: No description for 2d8qA was found.

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.48298025894013 bayes_pls_golite062009
nucleic acid binding 2.27695396544623 bayes_pls_golite062009
DNA binding 2.13220564234684 bayes_pls_golite062009
binding 2.04387193075129 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.41949477529902 bayes_pls_golite062009
transcription activator activity 0.570282420961288 bayes_pls_golite062009
protein binding 0.520486355666439 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [115-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AATEGNDEEE LPRLNSSGSG SGVLSTSVSL TNGSSSVYPS AITQKTGAGG ETLVEVGRSK  60
   61 TYTPMADDIC HVLKFECVVV NAETKQNVGL SCTILTSRVI PAPSPSPRRL ISISGTDVTG 120
  121 HLDSNGRPLS M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 2b3hA
Description: Crystal structure of Human Methionine Aminopeptidase Type I with a third cobalt in the active site
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [246-602]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTFTVLSYNI LSDTYASSDI YSYCPTWALA WTYRRQNLLR EIVKYRADIV CLQEVQNDHF  60
   61 EEFFLPELDK HGYQGLFKRK TNEVFIGNTN TIDGCATFFR RDRFSHVKKY EVEFNKAAQS 120
  121 LTEAIIPVSQ KKNALNRLVK DNVALIVVLE AKFGSQAADN PGKRQLLCVA NTHVNVPHEL 180
  181 KDVKLWQVHT LLKGLEKIAA SADIPMLVCG DFNTVPASAP HTLLAVGKVD PLHPDLMVDP 240
  241 LGILRPHSKL THQLPLVSAY SQFAKMGGNV ITEQQRRRLD PASSEPLFTN CTRDFIGTLD 300
  301 YIFYTADTLT VESLLELLDE ESLRKDTALP SPEWSSDHIA LLAEFRCMPR ARRNNIL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1e9nA
Description: DNA repair endonuclease Hap1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 3.28400034252781 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 3.04161110413795 bayes_pls_golite062009
DNA binding 2.38216646754749 bayes_pls_golite062009
transcription regulator activity 2.37867140645121 bayes_pls_golite062009
nucleic acid binding 2.37728600449241 bayes_pls_golite062009
nuclease activity 1.78432551160775 bayes_pls_golite062009
catalytic activity 1.76511376991978 bayes_pls_golite062009
binding 1.74593496417303 bayes_pls_golite062009
deoxyribonuclease activity 1.6713040226181 bayes_pls_golite062009
transcription coactivator activity 1.51022821676155 bayes_pls_golite062009
exonuclease activity 1.44893971411928 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.25010124971419 bayes_pls_golite062009
ribonuclease activity 0.934548175624486 bayes_pls_golite062009
transcription activator activity 0.885026804340494 bayes_pls_golite062009
transcription factor binding 0.77254170640454 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.738975226345995 bayes_pls_golite062009
exodeoxyribonuclease activity 0.73001958440393 bayes_pls_golite062009
transcription cofactor activity 0.58884884939295 bayes_pls_golite062009
protein binding 0.476649214025345 bayes_pls_golite062009
endonuclease activity 0.288539805949629 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 0.228910502815798 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.100365481550461 bayes_pls_golite062009
phosphatase activity 0.00559251346312178 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle