| Protein: | AP2A2_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 1013 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AP2A2_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
699.0 | [0..1] | [1013..1] |
|
Region A: Residues: [1-636] |
1 11 21 31 41 51
| | | | | |
1 MTGMRGLSVF ISDVRNCQNK EAERLRVDKE LGNIRTCFKN EKVLTPYKKK KYVWKMLYIH 60
61 MLGYDVDFGH MEAVSLISAP KYPEKQVGYI VTSCLLNENH DFLKLAINTV RNDIIGRNET 120
121 FQCLALTLVG NIGGRDFAES LAPDVQKLLI SSSCRPLVRK KAALCLLRLF RKNPDAVNVD 180
181 GWADRMAQLL DERDLGVLTS STSLLVALVS NNHEAYSSCL PKCVKILERL ARNQDVPQEY 240
241 TYYGIPSPWL QVKAMRALQY FPTIEDPSTR KALFEVLQRI LMGTDVVKNV NKNNASHAVL 300
301 FEALSLVMHL DAEKEMMSQC VALLGKFISV REPNIRYLGL ENMTRMLMVT DVQDIIKKHQ 360
361 SQIITSLKDP DISIRRRALD LLYGMCDVSN AKDIVEELLQ YLSTAEFSMR EELSLKAAIL 420
421 AEKFAPDLSW YVDVILQLID KAGDFVSDDI WFRVVQFVTN NEDLQPYAAS KAREYMDKIA 480
481 IHETMVKVSA YILGEYGHLL ARQPGCSASE LFSILHEKLP TVSTPTIPIL LSTYAKLLMH 540
541 AQPPDPELQK KVWAVFKKYE SCIDVEIQQR AVEYFELSKK GPAFMDVLAE MPKFPERQSS 600
601 LIKKAENVED TADQSAIKLR AQQQPSNAIV LADPQP
|
| Detection Method: |  |
| Confidence: | 96.0 |
| Match: | 1gw5A |
| Description: | Adaptin alpha C subunit N-terminal fragment |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| clathrin binding | 4.70716704570713 | bayes_pls_golite062009 |
| protein transporter activity | 4.58709163830613 | bayes_pls_golite062009 |
| transporter activity | 2.48700774379895 | bayes_pls_golite062009 |
| binding | 2.4389817190572 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.26725422172281 | bayes_pls_golite062009 |
| protein binding | 1.63705839411934 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 1.4515576307774 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.28481004323799 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.09652988954158 | bayes_pls_golite062009 |
| signal transducer activity | 0.877307852212156 | bayes_pls_golite062009 |
| molecular transducer activity | 0.877307852212156 | bayes_pls_golite062009 |
| signal sequence binding | 0.57106697498903 | bayes_pls_golite062009 |
| nuclear localization sequence binding | 0.342853430440159 | bayes_pls_golite062009 |
| nucleic acid binding | 0.294257360897755 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.252495966234234 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.248585912061178 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.226380819487924 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.217517113570989 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.178770060806735 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 0.175241020572885 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 0.174922130116569 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.100181463251306 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0635404099346928 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.0548082069333885 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.052195223119721 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.0405268469927988 | bayes_pls_golite062009 |
|
Region A: Residues: [637-733] |
1 11 21 31 41 51
| | | | | |
1 VNGAPPPLKV PILSGSTDPE SVARSLSHPN GTLSNIDPQT PSPDLLSDLL GPLAIEAPPG 60
61 AVSYEQHGPV GAEGVPDEID GSAIVPVEEQ TNTVELI
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [734-1013] |
1 11 21 31 41 51
| | | | | |
1 GNIAERFHAL CLKDSGVLYE DPHIQIGIKA EWRGHHGRLV LFMGNKNTSP LTSVQALILP 60
61 PAHLRLDLSP VPDTIPPRAQ VQSPLEVMNI RPSRDVAVLD FSYKFGTNVV SAKLRIPATL 120
121 NKFLQPLQLT SEEFFPQWRA ISGPPLKLQE VVRGVRPLAL PEMANLFNSF HVTICPGLDP 180
181 NPNNLVASTT FYSETTGAML CLARIETDPA DRTQLRLTVG SGDPTLTFEL KEFIKEQLIT 240
241 IPMGSRALVP AAGPAPSPAV QPPSPAALAD DPGAMLAGLL
|
| Detection Method: | |
| Confidence: | 78.522879 |
| Match: | 1w80A |
| Description: | Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170 |
Matching Structure (courtesy of the PDB): |
|
