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View Structure Prediction Details

Protein: GLYC7_ARATH
Organism: Arabidopsis thaliana
Length: 598 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLYC7_ARATH.

Description E-value Query
Range
Subject
Range
gi|21537165 - gi|21537165|gb|AAM61506.1| putative hydroxymethyltransferase [Arabidopsis thaliana]
454.0 [0..21] [598..1]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLSRSQTNF QLGFGCSHAS MTPTPTPRAP IADDSINLQV DQSFRSLPTT FSPIPLQLLE  60
   61 QKAEKTTTVD EPKKDGGGGG DQKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [85-598]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEHFRILGHH MCLKRQRDCP LLLTQSKHPK RSSIGDSDLE SRRAAVRAWG DQPIHLADPD  60
   61 IHELMEKEKQ RQVRGIELIA SENFVCRAVM EALGSHLTNK YSEGMPGARY YTGNQYIDQI 120
  121 ENLCIERALT AFGLESDKWG VNVQPYSCTS ANFAVYTGLL LPGERIMGLD SPSGGHMSHG 180
  181 YCTPGGKKIS AASIFFESFP YKVNPQTGYI DYDKLEDKAL DYRPKILICG GSSYPRDWDF 240
  241 ARVRQIADKC GAVLMCDMAH ISGLVATKEC SNPFDHCDIV TSTTHKGLRG PRGGIIFYRR 300
  301 GPKIRKQGHH SSHCDTSTHY DLEEKINFAV FPSLQGGPHN NHIAALAIAL KQVATPEYKA 360
  361 YIQQMKKNAQ ALAAALLRRK CRLVTGGTDN HLLLWDLTPM GLTGKVYEKV CEMCHITLNK 420
  421 TAIFGDNGTI SPGGVRIGTP AMTTRGCIES DFETMADFLI KAAQITSALQ REHGKSHKEF 480
  481 VKSLCTNKDI AELRNRVEAF ALQYEMPASL IRIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.522879
Match: 2a7vA
Description: Human mitochondrial serine hydroxymethyltransferase 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-aspartate:2-oxoglutarate aminotransferase activity 3.359406422625 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 3.2128372762799 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 3.2128372762799 bayes_pls_golite062009
transferase activity 2.59075614411581 bayes_pls_golite062009
5-aminolevulinate synthase activity 2.47911083054773 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 2.1692959843619 bayes_pls_golite062009
transcription regulator activity 1.67701710033155 bayes_pls_golite062009
DNA binding 1.4774443071095 bayes_pls_golite062009
nucleic acid binding 1.39741122443159 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.19150094103499 bayes_pls_golite062009
transcription factor activity 1.15775909410582 bayes_pls_golite062009
N-succinyltransferase activity 1.14675852378654 bayes_pls_golite062009
binding 1.09053123792737 bayes_pls_golite062009
structural molecule activity 0.754675308623467 bayes_pls_golite062009
methyltransferase activity 0.681623261233707 bayes_pls_golite062009
vitamin binding 0.66463470119531 bayes_pls_golite062009
protein binding 0.613130945854863 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.60304280865376 bayes_pls_golite062009
L-allo-threonine aldolase activity 0.500744432308415 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 0.271623203801431 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle