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View Structure Prediction Details

Protein: gi|157502193, gi...
Organism: Homo sapiens
Length: 376 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|157502193, gi....

Description E-value Query
Range
Subject
Range
gi|73982052 - gi|73982052|ref|XP_848457.1| PREDICTED: similar to 26S proteasome non-ATPase regulatory subunit 13 (...
0.0 [1..376] [1..376]
gi|123982712, gi... - gi|60655523|gb|AAX32325.1| proteasome 26S subunit 13 [synthetic construct], gi|123997379|gb|ABM86291...
PSMD13 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
gi|114635315 - gi|114635315|ref|XP_001144380.1| PREDICTED: proteasome 26S non-ATPase subunit 13 isoform 3 [Pan trog...
0.0 [1..376] [1..376]
gi|61372825, gi|... - gi|61372825|gb|AAX43919.1| proteasome 26S subunit 13 [synthetic construct], gi|32880133|gb|AAP88897....
0.0 [1..376] [1..376]
PSD13_BOVIN - 26S proteasome non-ATPase regulatory subunit 13 OS=Bos taurus GN=PSMD13 PE=2 SV=1
0.0 [1..376] [1..376]
PSD13_RAT - 26S proteasome non-ATPase regulatory subunit 13 OS=Rattus norvegicus GN=Psmd13 PE=1 SV=1
0.0 [1..376] [1..376]
PSD13_CHICK - 26S proteasome non-ATPase regulatory subunit 13 OS=Gallus gallus GN=PSMD13 PE=1 SV=1
0.0 [1..376] [1..376]
gi|74188108 - gi|74188108|dbj|BAE37156.1| unnamed protein product [Mus musculus]
0.0 [1..376] [1..376]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDVPGFLQQ SQNSGPGQPA VWHRLEELYT KKLWHQLTLQ VLDFVQDPCF AQGDGLIKLY  60
   61 ENFISEFEHR VNPLSLVEII LHVVRQMTDP NVALTFLEKT REKVKSSDEA VILCKTAIGA 120
  121 LKLNIGDLQV TKETIEDVEE MLNNLPGVTS VHSRFYDLSS KYYQTIGNHA SYYKDALRFL 180
  181 GCV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [184-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIKDLPVSEQ QERAFTLGLA GLLGEGVFNF GELLMHPVLE SLRNTDRQWL IDTLYAFNSG  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [244-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVERFQTLKT AWGQQPDLAA NEAQLLRKIQ LLCLMEMTFT RPANHRQLTF EEIAKSAKIT  60
   61 VNEVELLVMK ALSVGLVKGS IDEVDKRVHM TWVQPRVLDL QQIKGMKDRL EFWCTDVKSM 120
  121 EMLVEHQAHD ILT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.14
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.45730892915196 bayes_pls_golite062009
binding 3.37660003833383 bayes_pls_golite062009
DNA binding 3.14200456972385 bayes_pls_golite062009
nucleic acid binding 3.10521633426493 bayes_pls_golite062009
transcription factor activity 2.53044123488453 bayes_pls_golite062009
hydrolase activity 2.37143167527915 bayes_pls_golite062009
sequence-specific DNA binding 1.81719906294261 bayes_pls_golite062009
transcription activator activity 1.74538136688763 bayes_pls_golite062009
structural constituent of ribosome 1.48815906385664 bayes_pls_golite062009
transcription repressor activity 0.914435149747979 bayes_pls_golite062009
protein binding 0.726445167461826 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.224432853777564 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.142921675412538 bayes_pls_golite062009
small conjugating protein ligase activity 0.124542865343065 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle