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View Structure Prediction Details

Protein: gi|195344085, gi...
Organism: Drosophila sechellia
Length: 374 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|195344085, gi....

Description E-value Query
Range
Subject
Range
Antp-PL, Antp-PJ... - The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is...
152.0 [0..1] [374..1]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMSTNNCES MTSYFTNSYM GADMHHGHYP GNGVTDLDAQ QMHHYSQNAN HQGNMPYPRF  60
   61 PPYDRMPYYN GQGMDQQQQH QVYSRPDSPS SQVGGVMPQA QTNGQLGVPQ QQQQQQQQPS 120
  121 QNQQQQQAQQ APQQLQQQLP QVTQQVTHPQ QQQQQPVVYA SCKLQAAVGG LGMVPEGGSP 180
  181 PLVDQMSGHH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [191-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAQMTLPHH MGHPQAQLGY TDVGVPDVTE VHQNHHNMGM YQQQSGVPPV GAPPQGMMHQ  60
   61 GQGPPQMHQG HPGQHTPPSQ NPNSQSSGMP SPLYPWMRSQ FERKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [296-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRQTYTRYQT LELEKEFHFN RYLTRRRRIE IAHALCLTER QIKIWFQNRR MKWKKENKTK  60
   61 GEPGSGGEGD EITPPNSPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.30103
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.6809639302471 bayes_pls_golite062009
DNA binding 2.45264254102339 bayes_pls_golite062009
nucleic acid binding 2.32767577674158 bayes_pls_golite062009
binding 2.12643314274039 bayes_pls_golite062009
transcription factor activity 1.9610710007594 bayes_pls_golite062009
sequence-specific DNA binding 0.71974400731667 bayes_pls_golite062009
protein binding 0.57484570028668 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.328460252819506 bayes_pls_golite062009
transcription repressor activity 0.245215140763955 bayes_pls_golite062009
transcription activator activity 0.0177888191364471 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle