YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168466751, gi...
Organism:	Salmonella enterica subsp. enterica serovar Newport str. SL317
Length:	513 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168466751, gi....

Description	E-value	Query Range	Subject Range
gi\|56126872, gi\|... - gi\|56412615\|ref\|YP_149690.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Paratyp... gi\|197361550, gi... - gi\|197361550\|ref\|YP_002141186.1\| exopolyphosphatase [Salmonella enterica subsp. enterica serovar Par...	0.0	[1..513]	[1..513]
gi\|187731393, gi... - gi\|75178107\|ref\|ZP_00698166.1\| COG0248: Exopolyphosphatase [Shigella boydii BS512], gi\|187731393\|ref... gi\|82544949, gi\|... - gi\|82544949\|ref\|YP_408896.1\| exopolyphosphatase [Shigella boydii Sb227], gi\|81246360\|gb\|ABB67068.1\| ...	0.0	[1..513]	[1..513]
gi\|82777881, gi\|... - gi\|82777881\|ref\|YP_404230.1\| exopolyphosphatase [Shigella dysenteriae Sd197], gi\|81242029\|gb\|ABB6273...	0.0	[1..513]	[1..513]
gi\|15832618, gi\|... - gi\|15832618\|ref\|NP_311391.1\| exopolyphosphatase [Escherichia coli O157:H7 str. Sakai], gi\|13362834\|d... gi\|89109308, gi\|... - gi\|89109308\|ref\|AP_003088.1\| exopolyphosphatase [Escherichia coli str. K-12 substr. W3110], gi\|18055... gi\|91211823, gi\|... - gi\|91211823\|ref\|YP_541809.1\| exopolyphosphatase [Escherichia coli UTI89], gi\|91073397\|gb\|ABE08278.1\|... PPX_ECOLI - Exopolyphosphatase (EC 3.6.1.11) (ExopolyPase) (Metaphosphatase) - Escherichia coli PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ppx PE=3 SV=2 gi\|188017022, gi... - gi\|188017022\|gb\|EDU55144.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4113], gi\|168748440\|... PPX_ECO57 - Exopolyphosphatase OS=Escherichia coli O157:H7 GN=ppx PE=1 SV=2 gi\|168756273, gi... - gi\|189356554\|gb\|EDU74973.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4401], gi\|168756273\|... EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos... gi\|168773585, gi... - gi\|187770642\|gb\|EDU34486.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4196], gi\|168773585\|... gi\|12516890, gi\|... - gi\|15803025\|ref\|NP_289055.1\| exopolyphosphatase [Escherichia coli O157:H7 EDL933], gi\|12516890\|gb\|AA... gi\|189003181, gi... - gi\|189003181\|gb\|EDU72167.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4076], gi\|168778467\|... gi\|189372364, gi... - gi\|189372364\|gb\|EDU90780.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC869], gi\|168787847\|r... gi\|209398375, gi... - gi\|209398375\|ref\|YP_002271971.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4115], gi\|20915... gi\|209913238, gi... - gi\|209919979\|ref\|YP_002294063.1\| exopolyphosphatase [Escherichia coli SE11], gi\|209913238\|dbj\|BAG783... gi\|217319566, gi... - gi\|217327199\|ref\|ZP_03443282.1\| exopolyphosphatase [Escherichia coli O157:H7 str. TW14588], gi\|21731... EG11403 - exopolyphosphatase / Exopolyphosphatase; inhibited by pppGpp and ppGpp, also has guanosine pentaphos... gi\|218559426, gi... - gi\|218559426\|ref\|YP_002392339.1\| exopolyphosphatase [Escherichia coli S88], gi\|218366195\|emb\|CAR0394... gi\|218696129, gi... - gi\|218696129\|ref\|YP_002403796.1\| exopolyphosphatase [Escherichia coli 55989], gi\|218352861\|emb\|CAU98... gi\|254794447, gi... - gi\|254794447\|ref\|YP_003079284.1\| exopolyphosphatase [Escherichia coli O157:H7 str. TW14359], gi\|2545... gi\|218706001, gi... - gi\|218706001\|ref\|YP_002413520.1\| exopolyphosphatase [Escherichia coli UMN026], gi\|218433098\|emb\|CAR1... gi\|253974377, gi... - gi\|254162476\|ref\|YP_003045584.1\| exopolyphosphatase [Escherichia coli B str. REL606], gi\|253974377\|g... gi\|253323650, gi... - gi\|254289237\|ref\|YP_003054985.1\| exopolyphosphatase [Escherichia coli BL21(DE3)], gi\|253978544\|gb\|AC... gi\|251785827, gi... - gi\|251785827\|ref\|YP_003000131.1\| hypothetical protein B21_02356 [Escherichia coli BL21], gi\|24237810... gi\|168798872, gi... - gi\|189378553\|gb\|EDU96969.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC508], gi\|168798872\|r... gi\|238861059, gi... - gi\|238901667\|ref\|YP_002927463.1\| exopolyphosphatase [Escherichia coli BW2952], gi\|238861059\|gb\|ACR63... gi\|169754142, gi... - gi\|170019214\|ref\|YP_001724168.1\| exopolyphosphatase [Escherichia coli ATCC 8739], gi\|169754142\|gb\|AC... gi\|226901374, gi... - gi\|237705008\|ref\|ZP_04535489.1\| exopolyphosphatase [Escherichia sp. 3_2_53FAA], gi\|226901374\|gb\|EEH8... gi\|74313028, gi\|... - gi\|74313028\|ref\|YP_311447.1\| exopolyphosphatase [Shigella sonnei Ss046], gi\|73856505\|gb\|AAZ89212.1\| ... gi\|169889947, gi... - gi\|170082112\|ref\|YP_001731432.1\| exopolyphosphatase [Escherichia coli str. K-12 substr. DH10B], gi\|1... gi\|227835882, gi... - gi\|227887532\|ref\|ZP_04005337.1\| exopolyphosphatase [Escherichia coli 83972], gi\|227835882\|gb\|EEJ4634... PPX_ECOL6 - Exopolyphosphatase OS=Escherichia coli O6 GN=ppx PE=3 SV=2 gi\|170682766, gi... - gi\|170682766\|ref\|YP_001744686.1\| exopolyphosphatase [Escherichia coli SMS-3-5], gi\|170520484\|gb\|ACB1... gi\|195936644 - gi\|195936644\|ref\|ZP_03082026.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4024] gi\|208728650, gi... - gi\|208808849\|ref\|ZP_03251186.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4206], gi\|208728... gi\|208814562, gi... - gi\|208814562\|ref\|ZP_03255891.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4045], gi\|208735... gi\|208739064, gi... - gi\|208818941\|ref\|ZP_03259261.1\| exopolyphosphatase [Escherichia coli O157:H7 str. EC4042], gi\|208739... gi\|194423464, gi... - gi\|83586849\|ref\|ZP_00925480.1\| COG0248: Exopolyphosphatase [Escherichia coli 101-1], gi\|194437658\|re... gi\|193064767, gi... - gi\|75257309\|ref\|ZP_00728833.1\| COG0248: Exopolyphosphatase [Escherichia coli E22], gi\|193064767\|ref\|... gi\|188493752, gi... - gi\|75515843\|ref\|ZP_00737978.1\| COG0248: Exopolyphosphatase [Escherichia coli 53638], gi\|188493752\|re... gi\|157078836, gi... - gi\|75187254\|ref\|ZP_00700521.1\| COG0248: Exopolyphosphatase [Escherichia coli E24377A], gi\|157156806\|... gi\|75211469, gi\|... - gi\|75211469\|ref\|ZP_00711559.1\| COG0248: Exopolyphosphatase [Escherichia coli B171], gi\|194427254\|ref... gi\|117624686, gi... - gi\|117624686\|ref\|YP_853599.1\| exopolyphosphatase [Escherichia coli APEC O1], gi\|115513810\|gb\|ABJ0188...	0.0	[1..513]	[1..513]
gi\|83570721, gi\|... - gi\|83570721\|ref\|ZP_00922164.1\| COG0248: Exopolyphosphatase [Shigella dysenteriae 1012], gi\|194432122...	0.0	[1..513]	[1..513]
gi\|24113830, gi\|... - gi\|24113830\|ref\|NP_708340.1\| exopolyphosphatase [Shigella flexneri 2a str. 301], gi\|24052920\|gb\|AAN4... gi\|30042131, gi\|... - gi\|30063876\|ref\|NP_838047.1\| exopolyphosphatase [Shigella flexneri 2a str. 2457T], gi\|30042131\|gb\|AA...	0.0	[1..513]	[1..513]
gi\|75196510, gi\|... - gi\|75196510\|ref\|ZP_00706580.1\| COG0248: Exopolyphosphatase [Escherichia coli HS], gi\|157161963\|ref\|Y...	0.0	[1..513]	[1..513]
gi\|110344256, gi... - gi\|110642664\|ref\|YP_670394.1\| exopolyphosphatase [Escherichia coli 536], gi\|110344256\|gb\|ABG70493.1\|... gi\|218690617, gi... - gi\|218690617\|ref\|YP_002398829.1\| exopolyphosphatase [Escherichia coli ED1a], gi\|218428181\|emb\|CAR090... gi\|191172938, gi... - gi\|75240140\|ref\|ZP_00724099.1\| COG0248: Exopolyphosphatase [Escherichia coli F11], gi\|191172938\|ref\|...	0.0	[1..513]	[1..513]
gi\|192958253, gi... - gi\|75237751\|ref\|ZP_00721767.1\| COG0248: Exopolyphosphatase [Escherichia coli E110019], gi\|193068301\|...	0.0	[1..513]	[1..513]
gi\|77629846, gi\|... - gi\|77629846\|ref\|ZP_00792432.1\| COG0248: Exopolyphosphatase [Yersinia pseudotuberculosis IP 31758], g... gi\|165937131, gi... - gi\|89104917\|ref\|ZP_01177447.1\| COG0248: Exopolyphosphatase [Yersinia pestis biovar Orientalis str. I... gi\|165926016, gi... - gi\|165926016\|ref\|ZP_02221848.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. F1991016]... gi\|165992796, gi... - gi\|166008414\|ref\|ZP_02229312.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. E1979001], g... gi\|166206438, gi... - gi\|166212507\|ref\|ZP_02238542.1\| exopolyphosphatase [Yersinia pestis biovar Antiqua str. B42003004], ... gi\|166960759, gi... - gi\|167421270\|ref\|ZP_02313023.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. MG05-1020... gi\|229681652, gi... - gi\|229901723\|ref\|ZP_04516845.1\| exopolyphosphatase [Yersinia pestis Nepal516], gi\|229681652\|gb\|EEO77... gi\|167056354, gi... - gi\|167424472\|ref\|ZP_02316225.1\| exopolyphosphatase [Yersinia pestis biovar Mediaevalis str. K1973002... Q668D7\|Q668D7_YERPS - Putative exopolyphosphatase - Yersinia pseudotuberculosis gi\|167467165 - gi\|167467165\|ref\|ZP_02331869.1\| exopolyphosphatase [Yersinia pestis FV-1] gi\|149365300, gi... - gi\|149365300\|ref\|ZP_01887335.1\| exopolyphosphatase [Yersinia pestis CA88-4125], gi\|149291713\|gb\|EDM4... gi\|169750119, gi... - gi\|170023585\|ref\|YP_001720090.1\| exopolyphosphatase [Yersinia pseudotuberculosis YPIII], gi\|16975011... gi\|145599461, gi... - gi\|145599461\|ref\|YP_001163537.1\| exopolyphosphatase [Yersinia pestis Pestoides F], gi\|145211157\|gb\|A... gi\|186896210, gi... - gi\|186896210\|ref\|YP_001873322.1\| exopolyphosphatase [Yersinia pseudotuberculosis PB1/+], gi\|18669923... gi\|229694778, gi... - gi\|229838412\|ref\|ZP_04458571.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. PEXU2], g... gi\|229701555, gi... - gi\|229895400\|ref\|ZP_04510572.1\| exopolyphosphatase [Yersinia pestis Pestoides A], gi\|229701555\|gb\|EE... gi\|25290375 - pir\|\|AF0345 probable exopolyphosphatase (EC 3.6.1.11) [imported] - Yersinia pestis (strain CO92) gi\|229898979, gi... - gi\|229898979\|ref\|ZP_04514123.1\| exopolyphosphatase [Yersinia pestis biovar Orientalis str. India 195... gi\|45437342, gi\|... - gi\|45442477\|ref\|NP_994016.1\| exopolyphosphatase [Yersinia pestis biovar Microtus str. 91001], gi\|454... gi\|22125295, gi\|... - gi\|22125295\|ref\|NP_668718.1\| exopolyphosphatase [Yersinia pestis KIM], gi\|21958171\|gb\|AAM84969.1\|AE0... gi\|218929900, gi... - gi\|218929900\|ref\|YP_002347775.1\| exopolyphosphatase [Yersinia pestis CO92], gi\|16123032\|ref\|NP_40634... gi\|51597119, gi\|... - gi\|51597119\|ref\|YP_071310.1\| exopolyphosphatase [Yersinia pseudotuberculosis IP 32953], gi\|51590401\|...	0.0	[1..512]	[1..513]

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Predicted Domain #1

Region A:
Residues: [1-513]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIYDKSPRP QEFAAVDLGS NSFHMVIARV VDGAMQIIGR LKQRVHLADG LGADNKLSEE  60
   61 AMERGLSCLS LFAERLQGFS PSSVCIVGTH TLRQAQNAAD FLKRAEKVIP YPIEIISGNE 120
  121 EARLIFMGVE HTQPEKGRKL VIDIGGGSTE LVIGENFEPR LVESRRMGCV SFAQLYFPGG 180
  181 VINKENFQRA RMAAAQKLET LTWQYRIQGW NVAMGASGTI KAAHEVLLAL GEKDGFITPE 240
  241 RLDKLKSEVL KHRSFNALSL PGLSEERKAV FVPGLAILCG VFDALAIREL RLSDGALREG 300
  301 VLYEMEGRFR HQDVRSRTAK SLANQYNIDR EQARRVLETT MQMYEQWQAQ QPKLAHPQLE 360
  361 ALLRWAAMLH EVGLNINHSG LHRHSAYILQ HSDLPGFNQE QQMMMATLVR YHRKAIKLDD 420
  421 MPRFTLFKKK QYLPLIQLLR LGVLLNNQRQ ATTTPPTLRL TTDDSHWTLC FPHDWFSQNA 480
  481 LVLLDLEKEQ QYWEAVTGWR LNIEEESSPE IAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	160.0
Match:	1u6zA
Description:	Structure of an E. coli Exopolyphosphatase: Insight into the processive hydrolysis of polyphosphate and its regulation
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	1.87760960987608	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.75615325783105	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.59605394946105	bayes_pls_golite062009
binding	1.25460196265758	bayes_pls_golite062009
polyphosphate kinase activity	1.21204737821821	bayes_pls_golite062009
protein binding	1.01732312833155	bayes_pls_golite062009
phosphoric diester hydrolase activity	0.924155015104714	bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity	0.641327801104871	bayes_pls_golite062009
transferase activity	0.569421514787167	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	0.532800957697682	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
adenyl nucleotide binding	0.232254847278069	bayes_pls_golite062009
ATP binding	0.20090931123533	bayes_pls_golite062009
adenyl ribonucleotide binding	0.164881755458122	bayes_pls_golite062009
protein kinase activity	0.0746500139691637	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: