YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213650576
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. J185
Length:	363 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213650576.

Description	E-value	Query Range	Subject Range
gi\|110343025, gi... - gi\|110641433\|ref\|YP_669163.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli 536]... gi\|26107927, gi\|... - gi\|26247526\|ref\|NP_753566.1\| translation-associated GTPase [Escherichia coli CFT073], gi\|26107927\|gb... gi\|191171076, gi... - gi\|75242007\|ref\|ZP_00725801.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|215486435, gi... - gi\|215486435\|ref\|YP_002328866.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli O... gi\|91071998, gi\|... - gi\|91210424\|ref\|YP_540410.1\| translation-associated GTPase [Escherichia coli UTI89], gi\|91071998\|gb\|... gi\|218426714, gi... - gi\|218689150\|ref\|YP_002397362.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli E... gi\|227836579, gi... - gi\|227886375\|ref\|ZP_04004180.1\| GTP-binding protein [Escherichia coli 83972], gi\|227836579\|gb\|EEJ470... gi\|218558132, gi... - gi\|218558132\|ref\|YP_002391045.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli S... gi\|237705165, gi... - gi\|237705165\|ref\|ZP_04535646.1\| translation-associated GTPase [Escherichia sp. 3_2_53FAA], gi\|226899... gi\|117623421, gi... - gi\|117623421\|ref\|YP_852334.1\| translation-associated GTPase [Escherichia coli APEC O1], gi\|115512545...	0.0	[1..363]	[1..363]
gi\|218431822, gi... - gi\|218704725\|ref\|YP_002412244.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli U... EG11404 - catalase inhibitor protein; ATPase, K+-dependent, ribosome-associated / Catalase inhibitor protein; ... YCHF_SHIFL - Ribosome-binding ATPase YchF OS=Shigella flexneri GN=ychF PE=3 SV=2 gi\|30062727, gi\|... - gi\|30062727\|ref\|NP_836898.1\| translation-associated GTPase [Shigella flexneri 2a str. 2457T], gi\|300... YCHF_ECO57 - Ribosome-binding ATPase YchF OS=Escherichia coli O157:H7 GN=ychF PE=3 SV=2 ENGD_ECOLI - GTP-dependent nucleic acid-binding protein engD - Escherichia coli gi\|24051506, gi\|... - gi\|24112602\|ref\|NP_707112.1\| translation-associated GTPase [Shigella flexneri 2a str. 301], gi\|24051... gi\|124500646, gi... - gi\|124528414\|ref\|ZP_01699724.1\| GTP-binding protein YchF [Escherichia coli B], gi\|124500646\|gb\|EAY48... gi\|75228263, gi\|... - gi\|75228263\|ref\|ZP_00714918.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|75233900, gi\|... - gi\|75233900\|ref\|ZP_00718360.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... EG11404 - catalase inhibitor protein; ATPase, K+-dependent, ribosome-associated / Catalase inhibitor protein; ... gi\|192925613, gi... - gi\|75255061\|ref\|ZP_00726966.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|81240691, gi\|... - gi\|82776543\|ref\|YP_402892.1\| translation-associated GTPase [Shigella dysenteriae Sd197], gi\|81240691... gi\|81245754, gi\|... - gi\|82544343\|ref\|YP_408290.1\| translation-associated GTPase [Shigella boydii Sb227], gi\|81245754\|gb\|A... gi\|189356358, gi... - gi\|189356358\|gb\|EDU74777.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4401], gi\|1687... gi\|194436983, gi... - gi\|83587347\|ref\|ZP_00925975.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168750762, gi... - gi\|188015094\|gb\|EDU53216.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4113], gi\|1687... gi\|187730029, gi... - gi\|75179198\|ref\|ZP_00699216.1\| COG0012: Predicted GTPase, probable translation factor [Shigella boyd... gi\|189360083, gi... - gi\|189360083\|gb\|EDU78502.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4486], gi\|1687... gi\|157157840, gi... - gi\|75190257\|ref\|ZP_00703524.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168764411, gi... - gi\|189365599\|gb\|EDU84015.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4501], gi\|1687... gi\|75195356, gi\|... - gi\|75195356\|ref\|ZP_00705426.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168782557, gi... - gi\|189000062\|gb\|EDU69048.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|75212641, gi\|... - gi\|75212641\|ref\|ZP_00712639.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168777787, gi... - gi\|187767045\|gb\|EDU30889.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4196], gi\|1687... gi\|4062787, gi\|8... - gi\|89108048\|ref\|AP_001828.1\| predicted GTP-binding protein [Escherichia coli str. K-12 substr. W3110... gi\|13361173, gi\|... - gi\|15830962\|ref\|NP_309735.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli O157:... gi\|110805208, gi... - gi\|110805208\|ref\|YP_688728.1\| translation-associated GTPase [Shigella flexneri 5 str. 8401], gi\|1106... gi\|208737744, gi... - gi\|208822259\|ref\|ZP_03262578.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4042], gi\|... gi\|208733066, gi... - gi\|208816418\|ref\|ZP_03257597.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|209911703, gi... - gi\|209918444\|ref\|YP_002292528.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli S... gi\|209160238, gi... - gi\|209398838\|ref\|YP_002270137.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4115], gi... gi\|238900434, gi... - gi\|238900434\|ref\|YP_002926230.1\| putative GTP-binding protein [Escherichia coli BW2952], gi\|23886245... gi\|218553757, gi... - gi\|218553757\|ref\|YP_002386670.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli I... gi\|254592073, gi... - gi\|254792673\|ref\|YP_003077510.1\| predicted GTP-binding protein [Escherichia coli O157:H7 str. TW1435... gi\|217318721, gi... - gi\|217328294\|ref\|ZP_03444376.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. TW14588], gi... gi\|218699910, gi... - gi\|218699910\|ref\|YP_002407539.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli I... gi\|218694717, gi... - gi\|218694717\|ref\|YP_002402384.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli 5... gi\|189375870, gi... - gi\|189375870\|gb\|EDU94286.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC508], gi\|16880... gi\|189372434, gi... - gi\|189372434\|gb\|EDU90850.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC869], gi\|16878... gi\|169888666, gi... - gi\|170080831\|ref\|YP_001730151.1\| GTP-binding protein [Escherichia coli str. K-12 substr. DH10B], gi\|... gi\|169755358, gi... - gi\|170020430\|ref\|YP_001725384.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli A... gi\|194434920, gi... - gi\|194434920\|ref\|ZP_03067165.1\| GTP-binding protein EngD [Shigella dysenteriae 1012], gi\|194416853\|g... gi\|170518703, gi... - gi\|170680985\|ref\|YP_001743991.1\| GTP-binding protein EngD [Escherichia coli SMS-3-5], gi\|170518703\|g... gi\|208806944, gi... - gi\|208806944\|ref\|ZP_03249281.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4206], gi\|... gi\|195938852 - gi\|195938852\|ref\|ZP_03084234.1\| translation-associated GTPase [Escherichia coli O157:H7 str. EC4024]	0.0	[1..363]	[1..363]
gi\|36785400, gi\|... - gi\|37525971\|ref\|NP_929315.1\| translation-associated GTPase [Photorhabdus luminescens subsp. laumondi...	0.0	[1..363]	[1..363]
gi\|170718049, gi... - gi\|32029378\|ref\|ZP_00132411.1\| COG0012: Predicted GTPase, probable translation factor [Haemophilus s... gi\|113460648, gi... - gi\|23468010\|ref\|ZP_00123584.1\| COG0012: Predicted GTPase, probable translation factor [Haemophilus s...	0.0	[1..363]	[1..363]
gi\|73855934, gi\|... - gi\|74312457\|ref\|YP_310876.1\| translation-associated GTPase [Shigella sonnei Ss046], gi\|73855934\|gb\|A...	0.0	[1..363]	[1..363]
gi\|197362220, gi... - gi\|197362220\|ref\|YP_002141857.1\| GTP-dependent nucleic acid-binding protein EngD [Salmonella enteric... gi\|56127552, gi\|... - gi\|56413295\|ref\|YP_150370.1\| GTP-dependent nucleic acid-binding protein EngD [Salmonella enterica su...	0.0	[1..363]	[1..363]
gi\|188490726, gi... - gi\|75511761\|ref\|ZP_00734390.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c...	0.0	[1..363]	[1..363]
gi\|54295492, gi\|... - gi\|54295492\|ref\|YP_127907.1\| translation-associated GTPase [Legionella pneumophila str. Lens], gi\|53... gi\|52842860, gi\|... - gi\|52842860\|ref\|YP_096659.1\| translation-associated GTPase [Legionella pneumophila subsp. pneumophil...	0.0	[1..363]	[1..363]
gi\|54298643, gi\|... - gi\|54298643\|ref\|YP_125012.1\| translation-associated GTPase [Legionella pneumophila str. Paris], gi\|5...	0.0	[1..363]	[1..363]
gi\|53733243 - gi\|53733243\|ref\|ZP_00156230.2\| COG0012: Predicted GTPase, probable translation factor [Haemophilus i... gi\|145638696, gi... - gi\|145638696\|ref\|ZP_01794305.1\| GTP-binding protein [Haemophilus influenzae PittII], gi\|145272291\|gb...	0.0	[1..363]	[1..363]

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Predicted Domain #1

Region A:
Residues: [1-363]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFKCGIVGL PNVGKSTLFN ALTKAGIEAA NFPFCTIEPN TGVVPMPDPR LDQLAEIVKP  60
   61 QRILPTTMEF VDIAGLVKGA SKGEGLGNQF LTNIRETEAI GHVVRCFEND NIIHVAGKVN 120
  121 PAEDIDVINT ELALADLDTC ERAIHRVQKK AKGGDKDAKA ELAALEKCLP HLAEAGMLRS 180
  181 LDLTDEDKAA IRYLSFLTLK PTMYIANVNE DGFENNPYLD QVREIAAKEG SVVVPVCAAV 240
  241 EADIAELDDD ERDEFMAELG LEEPGLNRVI RAGYRLLNLQ TYFTAGVKEV RAWTIPVGAT 300
  301 APQAAGKIHT DFEKGFIRAQ TIAFDDFITY KGEQGAKEAG KMRAEGKDYI VKDGDIMNFL 360
  361 FNV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	102.0
Match:	1jalA
Description:	YchF GTP-binding protein N-terminal domain; YchF GTP-binding protein, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transmembrane transporter activity	3.21952132654519	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	3.06972174097431	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	2.99135301692379	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.81945030670779	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.81104198554628	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
substrate-specific transporter activity	2.26558861202152	bayes_pls_golite062009
nucleic acid binding	2.11222585187695	bayes_pls_golite062009
ion transmembrane transporter activity	1.93408704555564	bayes_pls_golite062009
guanyl nucleotide binding	1.89320355239381	bayes_pls_golite062009
guanyl ribonucleotide binding	1.88721318481223	bayes_pls_golite062009
GTP binding	1.87900088157196	bayes_pls_golite062009
DNA binding	1.7904783386531	bayes_pls_golite062009
cation transmembrane transporter activity	1.72121792847307	bayes_pls_golite062009
transcription regulator activity	1.68903321260301	bayes_pls_golite062009
hydrolase activity	1.29060292615008	bayes_pls_golite062009
GTPase activity	1.23010905798386	bayes_pls_golite062009
purine ribonucleotide binding	1.21658213854831	bayes_pls_golite062009
ribonucleotide binding	1.21652144153182	bayes_pls_golite062009
purine nucleotide binding	1.21571071905795	bayes_pls_golite062009
nucleotide binding	1.20347573865566	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
transcription factor activity	0.603758349693077	bayes_pls_golite062009
structural constituent of ribosome	0.396187998943318	bayes_pls_golite062009
translation regulator activity	0.29096092258568	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.274994961137851	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	0.12351419478929	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: