YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213646978
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. J185
Length:	438 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213646978.

Description	E-value	Query Range	Subject Range
gi\|81242475, gi\|... - gi\|82778327\|ref\|YP_404676.1\| proline aminopeptidase P II [Shigella dysenteriae Sd197], gi\|81242475\|g...	0.0	[1..438]	[4..441]
gi\|192930878, gi... - gi\|75258508\|ref\|ZP_00729930.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli E22], gi\|193063601\|... gi\|75227226, gi\|... - gi\|75227226\|ref\|ZP_00714026.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli B7A], gi\|191169456\|... gi\|194426199, gi... - gi\|75212477\|ref\|ZP_00712501.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli B171], gi\|194426199... gi\|218362224, gi... - gi\|218555456\|ref\|YP_002388369.1\| proline aminopeptidase P II [Escherichia coli IAI1], gi\|218362224\|e...	0.0	[1..438]	[4..441]
gi\|227888458, gi... - gi\|227888458\|ref\|ZP_04006263.1\| proline aminopeptidase P II [Escherichia coli 83972], gi\|227834727\|g... gi\|26249325, gi\|... - gi\|26249325\|ref\|NP_755365.1\| proline aminopeptidase P II [Escherichia coli CFT073], gi\|26109733\|gb\|A...	0.0	[1..438]	[4..441]
gi\|30042476, gi\|... - gi\|30064219\|ref\|NP_838390.1\| proline aminopeptidase P II [Shigella flexneri 2a str. 2457T], gi\|30042...	0.0	[1..438]	[4..441]
gi\|82545470, gi\|... - gi\|82545470\|ref\|YP_409417.1\| proline aminopeptidase P II [Shigella boydii Sb227], gi\|81246881\|gb\|ABB... gi\|187730091, gi... - gi\|75178801\|ref\|ZP_00698837.1\| COG0006: Xaa-Pro aminopeptidase [Shigella boydii BS512], gi\|187730091...	0.0	[1..438]	[4..441]
gi\|218366669, gi... - gi\|218559900\|ref\|YP_002392813.1\| proline aminopeptidase P II [Escherichia coli S88], gi\|218366669\|em... gi\|237706445, gi... - gi\|237706445\|ref\|ZP_04536926.1\| xaa-Pro aminopeptidase [Escherichia sp. 3_2_53FAA], gi\|226899485\|gb\|... gi\|91212287, gi\|... - gi\|91212287\|ref\|YP_542273.1\| proline aminopeptidase P II [Escherichia coli UTI89], gi\|91073861\|gb\|AB... gi\|115514262, gi... - gi\|117625138\|ref\|YP_854126.1\| proline aminopeptidase P II [Escherichia coli APEC O1], gi\|115514262\|g...	0.0	[1..438]	[4..441]
gi\|75239251, gi\|... - gi\|75239251\|ref\|ZP_00723224.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli F11], gi\|191173252\|... gi\|110643056, gi... - gi\|110643056\|ref\|YP_670786.1\| proline aminopeptidase P II [Escherichia coli 536], gi\|110344648\|gb\|AB...	0.0	[1..438]	[4..441]
gi\|24053302, gi\|... - gi\|24114161\|ref\|NP_708671.1\| proline aminopeptidase P II [Shigella flexneri 2a str. 301], gi\|2405330...	0.0	[1..438]	[4..441]
gi\|253323295, gi... - gi\|254289580\|ref\|YP_003055328.1\| proline aminopeptidase P II [Escherichia coli BL21(DE3)], gi\|253978... gi\|242378439, gi... - gi\|251786166\|ref\|YP_003000470.1\| hypothetical protein B21_02703 [Escherichia coli BL21], gi\|24237843... gi\|253974721, gi... - gi\|254162820\|ref\|YP_003045928.1\| proline aminopeptidase P II [Escherichia coli B str. REL606], gi\|25... gi\|188494686, gi... - gi\|75515308\|ref\|ZP_00737492.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli 53638], gi\|18849468... gi\|192956131, gi... - gi\|75234636\|ref\|ZP_00718967.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli E110019], gi\|193070... gi\|75196860, gi\|... - gi\|75196860\|ref\|ZP_00706930.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli HS], gi\|157162368\|r... gi\|75187624, gi\|... - gi\|75187624\|ref\|ZP_00700891.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli E24377A], gi\|157158...	0.0	[1..438]	[4..441]
gi\|13363251, gi\|... - gi\|15833033\|ref\|NP_311806.1\| proline aminopeptidase P II [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|13363251, gi\|... - gi\|15833033\|ref\|NP_311806.1\| proline aminopeptidase P II [Escherichia coli O157:H7], gi\|13363251\|dbj... gi\|209760450, gi... - pir\|\|G85946 proline aminopeptidase P II [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|15803443, gi\|... - gi\|15803443\|ref\|NP_289476.1\| proline aminopeptidase P II [Escherichia coli O157:H7 EDL933], gi\|12517... gi\|254794857, gi... - gi\|254794857\|ref\|YP_003079694.1\| proline aminopeptidase P II [Escherichia coli O157:H7 str. TW14359]... gi\|217326697, gi... - gi\|217326697\|ref\|ZP_03442780.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. TW14588], gi\|2... gi\|195936526 - gi\|195936526\|ref\|ZP_03081908.1\| proline aminopeptidase P II [Escherichia coli O157:H7 str. EC4024] gi\|208733741, gi... - gi\|208812464\|ref\|ZP_03253793.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4045], gi\|20... gi\|208741670, gi... - gi\|208821547\|ref\|ZP_03261867.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4042], gi\|20... gi\|209398591, gi... - gi\|209398591\|ref\|YP_002272384.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4115], gi\|2... gi\|168775788, gi... - gi\|187768811\|gb\|EDU32655.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4196], gi\|168775... gi\|168778924, gi... - gi\|189003609\|gb\|EDU72595.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4076], gi\|168778... gi\|168785757, gi... - gi\|189373889\|gb\|EDU92305.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC869], gi\|1687857... gi\|189377684, gi... - gi\|189377684\|gb\|EDU96100.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC508], gi\|1688000... gi\|168747610, gi... - gi\|188017799\|gb\|EDU55921.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4113], gi\|168747... gi\|189358530, gi... - gi\|189358530\|gb\|EDU76949.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4401], gi\|168753... gi\|189369256, gi... - gi\|189369256\|gb\|EDU87672.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4501], gi\|168760... gi\|189363746, gi... - gi\|189363746\|gb\|EDU82165.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4486], gi\|168766...	0.0	[1..438]	[4..441]

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Predicted Domain #1

Region A:
Residues: [1-438]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQQEYQRRR QALLAQMQPG SAALIFAAPE ATRSADSEYP YRQSSDFWYF TGFNEPEAVL  60
   61 VLIKSDDTHN HSVLFNRVRD LTAEIWFGRR LGQDAAPEKL GVDRALAFSE INQQLFQLLN 120
  121 GLDVVYHAQG EYAYADEIVL AALEKLRKGS RQNLTAPATM TDWRPIVHEM RLFKSPEEIA 180
  181 VLRRAGEISA LAHIRAMEKC RPGMFEYQLE GEIHHEFNRH GARYPSYNTI VGSGENGCIL 240
  241 HYTENESEMR DGDLVLIDAG CEYKGYAGDI TRTFPVNGKF TPAQREIYDI VLESLETSLR 300
  301 LFRPGTSIQQ VTGEVVRIMI TGLVKLGILQ GEVDQLIAEN AHRPFFMHGL SHWLGLDVHD 360
  361 VGVYGPDRSR ILEPGMVLTV EPGLYIAPDA DVPEAYRGIG VRIEDDIVIT ETGNENLTAG 420
  421 VVKKADDIEA LMAAARQQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	113.0
Match:	1a16A
Description:	AMINOPEPTIDASE P FROM E. COLI WITH THE INHIBITOR PRO-LEU
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	2.13673980333304	bayes_pls_golite062009
metallopeptidase activity	1.75829852010848	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	1.72257981533668	bayes_pls_golite062009
hydrolase activity	1.67276591010352	bayes_pls_golite062009
protein binding	1.09505761344036	bayes_pls_golite062009
aminopeptidase activity	0.89399203910285	bayes_pls_golite062009
exopeptidase activity	0.762255574851485	bayes_pls_golite062009
binding	0.434085018482953	bayes_pls_golite062009
catalytic activity	0.148551873544128	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: