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View Structure Prediction Details

Protein: gi|46015905
Organism: Homo sapiens
Length: 198 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|46015905.

Description E-value Query
Range
Subject
Range
gi|2462498 - gi|2462498|emb|CAA72592.1| human leukocyte antigen-C alpha chain [Homo sapiens]
234.0 [0..2] [197..114]
gi|1389955 - gi|1389955|gb|AAB97500.1| MHC class I Sasc-G*01 [Saimiri sciureus]
234.0 [0..2] [197..105]
gi|46408921 - gi|46408921|emb|CAD89650.1| MHC class I antigen [Macaca mulatta]
234.0 [0..2] [197..103]
gi|37958135 - gi|37958135|gb|AAP40298.1| MHC class I antigen [Saimiri sciureus sciureus]
234.0 [0..2] [197..114]

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Predicted Domain #1
Region A:
Residues: [1-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPEDFVFQFK GMCYFTNGTE RVRLVTRYIY NREEYARFDS DVGVYRAVTP QGRPDAEYWN  60
   61 SQKEVLEGTR AELDTVCRHN YEVAFRGILQ RRVEPTVTIS PSRTEALNHH NLLVCSVTDF 120
  121 YPGQIKVRWF RNDQEETAGV VSTPLIRNGD WTFQILVMLE MTPQRGDVYT CHVEHPSLQS 180
  181 PITVEWRAQS ESAQSKVD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.522879
Match: 1uvqB
Description: Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptide antigen binding 5.63215326620472 bayes_pls_golite062009
olfactory receptor activity 4.58024710763591 bayes_pls_golite062009
MHC class I receptor activity 3.46497995701625 bayes_pls_golite062009
endogenous lipid antigen binding 3.43614151119962 bayes_pls_golite062009
peptide binding 3.38582773777562 bayes_pls_golite062009
receptor activity 2.90626534331365 bayes_pls_golite062009
transmembrane receptor activity 2.76189257722839 bayes_pls_golite062009
antigen binding 2.27076537618453 bayes_pls_golite062009
lipid antigen binding 2.09050740693882 bayes_pls_golite062009
natural killer cell lectin-like receptor binding 2.02925074238378 bayes_pls_golite062009
signal transducer activity 1.90212388691264 bayes_pls_golite062009
molecular transducer activity 1.90212388691264 bayes_pls_golite062009
binding 1.56292619248655 bayes_pls_golite062009
receptor binding 0.93639628171707 bayes_pls_golite062009
protein binding 0.901995290894522 bayes_pls_golite062009
exogenous lipid antigen binding 0.763929387638141 bayes_pls_golite062009
IgG binding 0.66334714003323 bayes_pls_golite062009
MHC class II receptor activity 0.251167772391909 bayes_pls_golite062009
G-protein coupled receptor activity 0.22724598043225 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle