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View Structure Prediction Details

Protein: TPS3_ARATH
Organism: Arabidopsis thaliana
Length: 730 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPS3_ARATH.

Description E-value Query
Range
Subject
Range
TPS2_ARATH - Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2 OS=Arabidopsis thaliana GN=TPS2 PE...
543.0 [0..1] [726..2]

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Predicted Domain #1
Region A:
Residues: [1-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYDNVCGER QTLLVVANRL PASAKRTGEH SWSLEMSPGG KFNLLVEKDA VSKSLAEMKC  60
   61 IPVFLNEVFD QYYNGYSNGI LWPILHHMGL PQEYDHDTIK TFETQYDAYK KANRMFLDVI 120
  121 KENYKDGDIV WCQDYHLMFL PQYLKEYNNK IKVGWFLHSP FPSSEIYKTL PSRSELLRSV 180
  181 LAADLISFHT YDFARHFVNT CTRILGVEGT HEGVVYQGRV TRVVVLPMGI YPNRFIKTCK 240
  241 LPEVIQQMNE LKDRFSGKKV ILGVDRLDMI KGIPQKYLGF EKFLDENPNW RDKIVLVQIA 300
  301 VPTRNEVPEY QKLKNQVHRL VGRINGRFGS VSSLPIHHMD CSVDSNYLCA LYAISDVMLV 360
  361 TSLRDGLNLV SHEFVACQEA KRGVLILSEF AGAGQSLGAG ALLVNPWNVT EVSSAIKKAL 420
  421 NMPYEERETR HRVNFKYVKT HSAEKWGFDF LSELNDAFDE SELQIRKIPH E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.69897
Match: 1uqtA
Description: Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 11.2045941324603 bayes_pls_golite062009
glucosyltransferase activity 8.25064561355471 bayes_pls_golite062009
UDP-glucosyltransferase activity 8.0463972704113 bayes_pls_golite062009
trehalose-phosphatase activity 7.58500038184065 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 3.70184884300914 bayes_pls_golite062009
catalytic activity 2.65148466065976 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.62403914335522 bayes_pls_golite062009
transferase activity 2.18054407163329 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.13085705769565 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 1.55280519670033 bayes_pls_golite062009
carbohydrate phosphatase activity 0.78952375993773 bayes_pls_golite062009
glycogen phosphorylase activity 0.607220464589157 bayes_pls_golite062009
binding 0.345236672370351 bayes_pls_golite062009
phosphorylase activity 0.296436712681472 bayes_pls_golite062009
mannosyltransferase activity 0.253888301381021 bayes_pls_golite062009
protein binding 0.198267161626932 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [472-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPQQDVIQRY SLSNNRLIIL NFGEYKIWLA AENGMFLKHT TEEWVTNMPQ NMNLDWVDGL  60
   61 KNVFKYFTDR TPRSFFEASK TSLVWNYEYA DVEFGRAQAR DLLQYLWAGP ISNASAEVVR 120
  121 GKYSVEVHAI GVTKEPEIGH ILGEIVHKKA MTTPIDYVFC SGYFLEKDED IYTFFESEIL 180
  181 SPKLSHETRS KSSSSNHSLE KKVSLNVLDL KQENYFSTAI GQARTKARYV VDSSHNVVNL 240
  241 LHKLAVANTT TTSVKKPNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1s2oA
Description: X-Ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp. PCC6803 at 1.40 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
trehalose-phosphatase activity 3.78859922218487 bayes_pls_golite062009
transporter activity 2.28749015584769 bayes_pls_golite062009
hydrolase activity 2.23636068759523 bayes_pls_golite062009
transmembrane transporter activity 2.17051010073814 bayes_pls_golite062009
substrate-specific transporter activity 2.14633664297706 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.05684652641195 bayes_pls_golite062009
ion transmembrane transporter activity 2.05060633349756 bayes_pls_golite062009
cation transmembrane transporter activity 1.84740904871745 bayes_pls_golite062009
catalytic activity 1.55296860681783 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.53201151596704 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.45647470429539 bayes_pls_golite062009
ATPase activity, coupled 1.44542004757594 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.42792997211574 bayes_pls_golite062009
ATPase activity 1.40341876769691 bayes_pls_golite062009
pyrophosphatase activity 1.352553895791 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1.33388154652051 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.33292469269496 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.33065047107664 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.31602086166435 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.28050944646617 bayes_pls_golite062009
active transmembrane transporter activity 0.194344891491143 bayes_pls_golite062009
phosphatase activity 0.159899259988948 bayes_pls_golite062009
cation-transporting ATPase activity 0.15490458026932 bayes_pls_golite062009
nucleic acid binding 0.143980906464589 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.103902756538853 bayes_pls_golite062009
primary active transmembrane transporter activity 0.053543166906854 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.041293091790546 bayes_pls_golite062009
binding 0.0209333912048011 bayes_pls_golite062009

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