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View Structure Prediction Details

Protein: gi|12084441, gi|...
Organism: Homo sapiens
Length: 298 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|12084441, gi|....

Description E-value Query
Range
Subject
Range
KLKB1_MOUSE, KAL... - Plasma kallikrein OS=Mus musculus GN=Klkb1 PE=1 SV=1, (P26262) Plasma kallikrein precursor (EC 3.4.2...
243.0 [0..4] [298..379]
gi|68358224 - gi|68358224|ref|XP_690065.1| PREDICTED: similar to marapsin [Danio rerio]
241.0 [0..2] [293..158]
KLKB1_RAT - Plasma kallikrein OS=Rattus norvegicus GN=Klkb1 PE=1 SV=1
238.0 [0..4] [293..379]
gi|119625028, gi... - gi|78191798|ref|NP_000883.2| plasma kallikrein B1 precursor [Homo sapiens], gi|63990061|gb|AAY40900....
236.0 [0..4] [294..379]
gi|197097302 - gi|197097302|ref|NP_001125987.1| plasma kallikrein B1 [Pongo abelii]
gi|55729915 - gi|55729915|emb|CAH91684.1| hypothetical protein [Pongo abelii]
234.0 [0..4] [294..341]

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Predicted Domain #1
Region A:
Residues: [1-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADPDESQSLS LCGMVWEHRK GTDYHKQPWQ AKISVIRPSK GHESCMGAVV SEYFVLTAAH  60
   61 CFTVDDKEHS IKVSVGGEKR DLEIEVVLFH PNYNINGKKE AGIPEFYDYD VALIKLKNKL 120
  121 KYGQTIRPIC LPCTEGTTRA LRLPPTTTCQ QQKEELLPAQ DIKALFVSEE EKKLTRKEVY 180
  181 IKNGDKKGSC ERDAQYAPGY DKVKDISEVV TPRFLCTGGV SPYADPNTCR GDSGGPLIVH 240
  241 KRSRFIQVGV ISWGVVDVCK NQKRQKQVPA HARDFHINLF QVLPWLKEKL QDEDLGFL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.69897
Match: 1dleA
Description: Factor B
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.45564952644664 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.04036142771923 bayes_pls_golite062009
serine-type peptidase activity 3.78205053779954 bayes_pls_golite062009
serine hydrolase activity 3.77549260274235 bayes_pls_golite062009
endopeptidase activity 3.68510728052076 bayes_pls_golite062009
serine-type endopeptidase activity 3.53730603466527 bayes_pls_golite062009
hydrolase activity 2.84725634540158 bayes_pls_golite062009
catalytic activity 1.77971907246438 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle