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View Structure Prediction Details

Protein: gi|10120782, gi|...
Organism: Homo sapiens
Length: 261 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|10120782, gi|....

Description E-value Query
Range
Subject
Range
gi|397971 - gi|397971|gb|AAC38002.1| dystrophin
271.0 [0..1] [261..244]
gi|457519 - gi|457519|gb|AAA35779.1| putative partial CDS for dystrophin; putative [Homo sapiens]
270.0 [0..1] [261..67]
gi|55391517 - gi|55391517|gb|AAH85236.1| Dmd protein [Mus musculus]
266.0 [0..1] [261..387]
gi|76659641 - gi|76659641|ref|XP_612974.2| PREDICTED: similar to dystrophin Dp140b isoform, partial [Bos taurus]
263.0 [0..1] [261..495]
gi|197099863 - gi|197099863|ref|NP_001125608.1| utrophin [Pongo abelii]
gi|55728615 - gi|55728615|emb|CAH91048.1| hypothetical protein [Pongo abelii]
261.0 [0..1] [261..327]

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Predicted Domain #1
Region A:
Residues: [1-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPASQHFLST SVQGPWERAI SPNKVPYYIN HETQTTCWDH PKMTELYQSL ADLNNVRFSA  60
   61 YRTAMKLRRL QKALCLDLLS LSAACDALDQ HNLKQNDQPM DILQIINCLT TIYDRLEQEH 120
  121 NNLVNVPLCV DMCLNWLLNV YDTGRTGRIR VLSFKTGIIS LCKAHLEDKY RYLFKQVASS 180
  181 TGFCDQRRLG LLLHDSIQIP RQLGEVASFG GSNIEPSVRS CFQFANNKPE IEAALFLDWM 240
  241 RLEPQSMVWL PVLHRVAAAE T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.522879
Match: 1eg3A
Description: Dystrophin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of muscle 5.54109779906915 bayes_pls_golite062009
acetylcholine transmembrane transporter activity 3.43985481301683 bayes_pls_golite062009
transcription regulator activity 3.2682543222543 bayes_pls_golite062009
binding 2.62219069341981 bayes_pls_golite062009
transcription activator activity 2.28375305944516 bayes_pls_golite062009
transcription factor binding 2.18630749239417 bayes_pls_golite062009
cytoskeletal protein binding 2.11906774871731 bayes_pls_golite062009
metal ion binding 2.11094352721028 bayes_pls_golite062009
cation binding 2.11094352721028 bayes_pls_golite062009
ion binding 2.10331783734535 bayes_pls_golite062009
transcription cofactor activity 2.07432061489599 bayes_pls_golite062009
transcription coactivator activity 2.02433252968502 bayes_pls_golite062009
actin binding 2.02356543483094 bayes_pls_golite062009
DNA binding 1.73924929536227 bayes_pls_golite062009
nucleic acid binding 1.53225451586959 bayes_pls_golite062009
protein binding 1.46903005775608 bayes_pls_golite062009
calcium ion binding 1.40919295397643 bayes_pls_golite062009
myosin binding 1.23881879879813 bayes_pls_golite062009
motor activity 1.08123526270094 bayes_pls_golite062009
nitric-oxide synthase binding 0.965098383344279 bayes_pls_golite062009
molecular transducer activity 0.933783050059916 bayes_pls_golite062009
signal transducer activity 0.933783050059916 bayes_pls_golite062009
microfilament motor activity 0.71766448962378 bayes_pls_golite062009
structural molecule activity 0.640474644163009 bayes_pls_golite062009
actin filament binding 0.512173584028638 bayes_pls_golite062009
myosin II heavy chain binding 0.308481284245779 bayes_pls_golite062009
catalytic activity 0.210712504691113 bayes_pls_golite062009
ion transmembrane transporter activity 0.209763469645099 bayes_pls_golite062009
transcription repressor activity 0.18603158355229 bayes_pls_golite062009
cation transmembrane transporter activity 0.183123873014372 bayes_pls_golite062009
myosin heavy chain binding 0.15875878144391 bayes_pls_golite062009
actin-dependent ATPase activity 0.1582139439683 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle