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View Structure Prediction Details

Protein: gi|6137498
Organism: Homo sapiens
Length: 325 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|6137498.

Description E-value Query
Range
Subject
Range
gi|50746879 - gi|50746879|ref|XP_426325.1| PREDICTED: similar to N-deacetylase/N-sulfotransferase (heparan glucosa...
289.0 [0..1] [325..681]
gi|76619364, gi|... - gi|76619366|ref|XP_878986.1| PREDICTED: similar to N-deacetylase/N-sulfotransferase (heparan glucosa...
285.0 [0..1] [325..549]
gi|109075487, gi... - gi|109075487|ref|XP_001098030.1| PREDICTED: similar to N-deacetylase/N-sulfotransferase (heparan glu...
285.0 [0..1] [325..549]
gi|55623118 - gi|55623118|ref|XP_526668.1| PREDICTED: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 [P...
284.0 [0..1] [325..548]
gi|5668903 - gi|5668903|gb|AAD46061.1|AF076605_1 heparan N-deacetylase/N-sulfotransferase 3 [Homo sapiens]
284.0 [0..1] [325..552]
gi|109467582, gi... - gi|62644302|ref|XP_342337.2| PREDICTED: similar to N-deacetylase/N-sulfotransferase (heparin glucosa...
284.0 [0..1] [325..548]

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Predicted Domain #1
Region A:
Residues: [1-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQTLPPVQLA QKYFQIFSEE KDPLWQDPCE DKRHKDIWSK EKTCDRFPKL LIIGPQKTGT  60
   61 TALYLFLGMH PDLSSNYPSS ETFEEIQFFN GHNYHKGIDW YMEFFPIPSN TTSDFYFEKS 120
  121 ANYFDSEVAP RRAAALLPKA KVLTILINPA DRAYSWYQHQ RAHDDPVALK YTFHEVITAG 180
  181 SDASSKLRAL QNRCLVPGWY ATHIERWLSA YHANQILVLD GKLLRTEPAK VMDMVQKFLG 240
  241 VTNTIDYHKT LAFDPKKGFW CQLLEGGKTK CLGKSKGRKY PEMDLDSRAF LKDYYRDHNI 300
  301 ELSKLLYKMG QTLPTWLRED LQNTR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.045757
Match: 1nstA
Description: Heparan sulfate N-deacetylase/N-sulfotransferase domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleoside-triphosphatase activity 1.02433892333256 bayes_pls_golite062009
pyrophosphatase activity 0.989469851846122 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.980088098062305 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.976945962392631 bayes_pls_golite062009
binding 0.837538244475264 bayes_pls_golite062009
ATPase activity 0.508559099342241 bayes_pls_golite062009
transporter activity 0.48424022775161 bayes_pls_golite062009
transmembrane transporter activity 0.43068338046008 bayes_pls_golite062009
hydrolase activity 0.410543385742586 bayes_pls_golite062009
ATPase activity, coupled 0.366003414070823 bayes_pls_golite062009
catalytic activity 0.234613562021476 bayes_pls_golite062009
primary active transmembrane transporter activity 0.229052859670546 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.221848871525989 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.190228662787185 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.186067331649217 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.185248585258315 bayes_pls_golite062009
active transmembrane transporter activity 0.0712149467387941 bayes_pls_golite062009

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