From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.672625641994] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitochondrial intermembrane space | 3.1832E-5 | 2 | 36 | 2 | 6292 |
organelle envelope lumen | 3.9411E-5 | 2 | 40 | 2 | 6292 |
mitochondrial envelope | 2.4514E-3 | 2 | 312 | 2 | 6292 |
integral to mitochondrial outer membrane | 4.1283E-3 | 2 | 13 | 1 | 6292 |
intrinsic to mitochondrial outer membrane | 4.1283E-3 | 2 | 13 | 1 | 6292 |
integral to mitochondrial membrane | 4.4455E-3 | 2 | 14 | 1 | 6292 |
mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
response to oxidative stress | 1.1854E-4 | 2 | 69 | 2 | 6292 |
protein import into mitochondrial intermembrane space | 2.5415E-3 | 2 | 8 | 1 | 6292 |
electron transport | 2.859E-3 | 2 | 9 | 1 | 6292 |
response to chemical stimulus | 3.6769E-3 | 2 | 382 | 2 | 6292 |
response to stress | 6.2277E-3 | 2 | 497 | 2 | 6292 |
phytosteroid metabolic process | 8.248E-3 | 2 | 26 | 1 | 6292 |
phytosteroid biosynthetic process | 8.248E-3 | 2 | 26 | 1 | 6292 |
ergosterol biosynthetic process | 8.248E-3 | 2 | 26 | 1 | 6292 |
ergosterol metabolic process | 8.248E-3 | 2 | 26 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
flavin-linked sulfhydryl oxidase activity | 6.3568E-4 | 2 | 2 | 1 | 6292 |
cytochrome-b5 reductase activity | 9.5344E-4 | 2 | 3 | 1 | 6292 |
oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor | 1.2712E-3 | 2 | 4 | 1 | 6292 |
thiol oxidase activity | 1.2712E-3 | 2 | 4 | 1 | 6292 |
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor | 1.5888E-3 | 2 | 5 | 1 | 6292 |
oxidoreductase activity | 1.9877E-3 | 2 | 281 | 2 | 6292 |
oxidoreductase activity, acting on sulfur group of donors | 6.3477E-3 | 2 | 20 | 1 | 6292 |
oxidoreductase activity, acting on NADH or NADPH | 6.6645E-3 | 2 | 21 | 1 | 6292 |