From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.738546401945] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
SHG1 |
|
|
|
SPP1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
Set1C/COMPASS complex | 1.4147E-6 | 2 | 8 | 2 | 6292 |
methyltransferase complex | 1.4147E-6 | 2 | 8 | 2 | 6292 |
histone methyltransferase complex | 1.4147E-6 | 2 | 8 | 2 | 6292 |
chromatin remodeling complex | 2.4511E-4 | 2 | 99 | 2 | 6292 |
nucleoplasm part | 1.5102E-3 | 2 | 245 | 2 | 6292 |
nucleoplasm | 1.7541E-3 | 2 | 264 | 2 | 6292 |
nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
histone methylation | 9.6001E-6 | 2 | 20 | 2 | 6292 |
protein amino acid alkylation | 1.3945E-5 | 2 | 24 | 2 | 6292 |
protein amino acid methylation | 1.3945E-5 | 2 | 24 | 2 | 6292 |
macromolecule methylation | 4.5626E-5 | 2 | 43 | 2 | 6292 |
methylation | 4.5626E-5 | 2 | 43 | 2 | 6292 |
one-carbon metabolic process | 7.5032E-5 | 2 | 55 | 2 | 6292 |
covalent chromatin modification | 1.9342E-4 | 2 | 88 | 2 | 6292 |
histone modification | 1.9342E-4 | 2 | 88 | 2 | 6292 |
chromatin modification | 7.0879E-4 | 2 | 168 | 2 | 6292 |
chromatin organization | 1.036E-3 | 2 | 203 | 2 | 6292 |
post-translational protein modification | 3.2108E-3 | 2 | 357 | 2 | 6292 |
protein modification process | 6.278E-3 | 2 | 499 | 2 | 6292 |
chromosome organization | 7.7677E-3 | 2 | 555 | 2 | 6292 |
macromolecule modification | 8.1649E-3 | 2 | 569 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
histone methyltransferase activity (H3-K4 specific) | 1.4147E-6 | 2 | 8 | 2 | 6292 |
histone methyltransferase activity | 1.819E-6 | 2 | 9 | 2 | 6292 |
histone-lysine N-methyltransferase activity | 1.819E-6 | 2 | 9 | 2 | 6292 |
lysine N-methyltransferase activity | 3.9411E-6 | 2 | 13 | 2 | 6292 |
protein-lysine N-methyltransferase activity | 3.9411E-6 | 2 | 13 | 2 | 6292 |
protein methyltransferase activity | 9.6001E-6 | 2 | 20 | 2 | 6292 |
N-methyltransferase activity | 1.5158E-5 | 2 | 25 | 2 | 6292 |
S-adenosylmethionine-dependent methyltransferase activity | 1.1171E-4 | 2 | 67 | 2 | 6292 |
methyltransferase activity | 2.304E-4 | 2 | 96 | 2 | 6292 |
transferase activity, transferring one-carbon groups | 2.4511E-4 | 2 | 99 | 2 | 6292 |