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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.870071754032]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
APL3
  • AP-2 adaptor complex
    		•
  • vesicle-mediated transport
    		•
  • molecular_function
    		•
    APS2
  • AP-2 adaptor complex
    		•
  • vesicle-mediated transport
    		•
  • molecular_function
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    clathrin coat of endocytic vesicle 3.0316E-7 2 4 2 6292
    clathrin-coated endocytic vesicle membrane 3.0316E-7 2 4 2 6292
    coated pit 3.0316E-7 2 4 2 6292
    AP-2 adaptor complex 3.0316E-7 2 4 2 6292
    endocytic vesicle membrane 3.0316E-7 2 4 2 6292
    clathrin-coated endocytic vesicle 3.0316E-7 2 4 2 6292
    endocytic vesicle 3.0316E-7 2 4 2 6292
    clathrin coat of coated pit 3.0316E-7 2 4 2 6292
    clathrin adaptor complex 2.2737E-6 2 10 2 6292
    clathrin vesicle coat 4.5979E-6 2 14 2 6292
    clathrin coat 4.5979E-6 2 14 2 6292
    AP-type membrane coat adaptor complex 4.5979E-6 2 14 2 6292
    clathrin coated vesicle membrane 5.3053E-6 2 15 2 6292
    clathrin-coated vesicle 2.3495E-5 2 31 2 6292
    vesicle coat 2.8346E-5 2 34 2 6292
    coated vesicle membrane 3.0063E-5 2 35 2 6292
    cytoplasmic vesicle membrane 3.0063E-5 2 35 2 6292
    vesicle membrane 3.0063E-5 2 35 2 6292
    membrane coat 3.552E-5 2 38 2 6292
    coated membrane 3.552E-5 2 38 2 6292
    cytoplasmic vesicle part 3.744E-5 2 39 2 6292
    plasma membrane part 8.0641E-5 2 57 2 6292
    coated vesicle 1.7194E-4 2 83 2 6292
    cytoplasmic vesicle 2.8654E-4 2 107 2 6292
    membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    cytoplasmic membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    vesicle 3.0291E-4 2 110 2 6292
    plasma membrane 1.8077E-3 2 268 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    vesicle-mediated transport 2.9119E-3 2 340 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle