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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.965842303143]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
SPC24
  • condensed nuclear chromosome, centromeric region
  • Ndc80 complex
  • condensed nuclear chromosome kinetochore
    		•
  • microtubule nucleation
  • chromosome segregation
    		•
  • structural constituent of cytoskeleton
    		•
    STU2
  • spindle microtubule
  • cell cortex
  • spindle pole body
  • condensed nuclear chromosome kinetochore
  • kinetochore
    		•
  • microtubule nucleation
  • mitotic spindle organization in nucleus
    		•
  • structural constituent of cytoskeleton
  • microtubule binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    condensed nuclear chromosome kinetochore 5.9419E-5 2 49 2 6292
    condensed chromosome kinetochore 5.9419E-5 2 49 2 6292
    condensed chromosome, centromeric region 7.5032E-5 2 55 2 6292
    condensed nuclear chromosome, centromeric region 7.5032E-5 2 55 2 6292
    kinetochore 8.9432E-5 2 60 2 6292
    chromosome, centromeric region 1.1171E-4 2 67 2 6292
    condensed nuclear chromosome 1.8468E-4 2 86 2 6292
    condensed chromosome 2.2085E-4 2 94 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    Ndc80 complex 1.2712E-3 2 4 1 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292
    spindle microtubule 5.3968E-3 2 17 1 6292
    microtubule 9.8303E-3 2 31 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    microtubule nucleation 1.2783E-5 2 23 2 6292
    microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
    microtubule-based process 3.0847E-4 2 111 2 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    mitotic spindle organization in nucleus 8.248E-3 2 26 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    structural constituent of cytoskeleton 6.9626E-5 2 53 2 6292
    structural molecule activity 2.8947E-3 2 339 2 6292
    microtubule binding 3.1764E-3 2 10 1 6292
    tubulin binding 6.3477E-3 2 20 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle