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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.967591761574]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RAD16
  • repairosome
  • nucleotide-excision repair factor 4 complex
    		•
  • nucleotide-excision repair, DNA damage recognition
    		•
  • DNA-dependent ATPase activity
  • damaged DNA binding
    		•
    RAD23
  • nucleotide-excision repair factor 2 complex
  • mitochondrion
  • repairosome
  • proteasome complex
    		•
  • nucleotide-excision repair, DNA damage recognition
  • negative regulation of protein catabolic process
  • ER-associated protein catabolic process
    		•
  • damaged DNA binding
  • protein binding, bridging
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    repairosome 3.0316E-7 2 4 2 6292
    nucleotide-excision repair complex 1.0611E-5 2 21 2 6292
    nucleotide-excision repair factor 2 complex 6.3568E-4 2 2 1 6292
    nucleotide-excision repair factor 4 complex 1.2712E-3 2 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nucleotide-excision repair, DNA damage recognition 1.0611E-6 2 7 2 6292
    nucleotide-excision repair 3.552E-5 2 38 2 6292
    negative regulation of protein catabolic process 6.3568E-4 2 2 1 6292
    negative regulation of catabolic process 6.3568E-4 2 2 1 6292
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    regulation of protein catabolic process 2.224E-3 2 7 1 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    negative regulation of protein metabolic process 5.0798E-3 2 16 1 6292
    response to stress 6.2277E-3 2 497 2 6292
    regulation of catabolic process 7.6148E-3 2 24 1 6292
    chromosome organization 7.7677E-3 2 555 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    damaged DNA binding 2.779E-6 2 11 2 6292
    DNA binding 1.6492E-3 2 256 2 6292
    protein binding, bridging 6.3477E-3 2 20 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle