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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.984402350027]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
APL2
  • AP-1 adaptor complex
    		•
  • vesicle-mediated transport
  • Golgi to vacuole transport
    		•
  • clathrin binding
    		•
    APM1
  • AP-1 adaptor complex
    		•
  • vesicle-mediated transport
  • Golgi to vacuole transport
    		•
  • clathrin binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    clathrin coat of trans-Golgi network vesicle 7.579E-7 2 6 2 6292
    AP-1 adaptor complex 7.579E-7 2 6 2 6292
    trans-Golgi network transport vesicle membrane 1.0611E-6 2 7 2 6292
    clathrin adaptor complex 2.2737E-6 2 10 2 6292
    trans-Golgi network transport vesicle 2.779E-6 2 11 2 6292
    clathrin vesicle coat 4.5979E-6 2 14 2 6292
    clathrin coat 4.5979E-6 2 14 2 6292
    AP-type membrane coat adaptor complex 4.5979E-6 2 14 2 6292
    clathrin coated vesicle membrane 5.3053E-6 2 15 2 6292
    transport vesicle membrane 5.3053E-6 2 15 2 6292
    Golgi-associated vesicle membrane 6.0632E-6 2 16 2 6292
    clathrin-coated vesicle 2.3495E-5 2 31 2 6292
    vesicle coat 2.8346E-5 2 34 2 6292
    coated vesicle membrane 3.0063E-5 2 35 2 6292
    cytoplasmic vesicle membrane 3.0063E-5 2 35 2 6292
    vesicle membrane 3.0063E-5 2 35 2 6292
    membrane coat 3.552E-5 2 38 2 6292
    coated membrane 3.552E-5 2 38 2 6292
    cytoplasmic vesicle part 3.744E-5 2 39 2 6292
    Golgi-associated vesicle 3.9411E-5 2 40 2 6292
    transport vesicle 5.0022E-5 2 45 2 6292
    Golgi membrane 5.9419E-5 2 49 2 6292
    coated vesicle 1.7194E-4 2 83 2 6292
    membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    cytoplasmic vesicle 2.8654E-4 2 107 2 6292
    cytoplasmic membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    vesicle 3.0291E-4 2 110 2 6292
    Golgi apparatus part 3.5475E-4 2 119 2 6292
    Golgi apparatus 7.3441E-4 2 171 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Golgi to vacuole transport 1.3945E-5 2 24 2 6292
    post-Golgi vesicle-mediated transport 1.151E-4 2 68 2 6292
    vacuolar transport 3.312E-4 2 115 2 6292
    Golgi vesicle transport 7.0879E-4 2 168 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    clathrin binding 2.779E-6 2 11 2 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle