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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.22990781184]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
DCP2
  • nucleus
  • cytoplasm
  • cytoplasmic mRNA processing body
    		•
  • deadenylation-independent decapping of nuclear-transcribed mRNA
  • deadenylation-dependent decapping of nuclear-transcribed mRNA
  • mRNA catabolic process
    		•
  • mRNA binding
  • m7G(5')pppN diphosphatase activity
  • hydrolase activity
    		•
    DCS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • cytoplasmic mRNA processing body
    		•
  • deadenylation-dependent decapping of nuclear-transcribed mRNA
    		•
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
  • m7G(5')pppN diphosphatase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    cytoplasmic mRNA processing body 5.3053E-6 2 15 2 6292
    ribonucleoprotein complex 6.6615E-3 2 514 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    deadenylation-dependent decapping of nuclear-transcribed mRNA 2.779E-6 2 11 2 6292
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1.7735E-5 2 27 2 6292
    nuclear-transcribed mRNA catabolic process 3.552E-5 2 38 2 6292
    mRNA catabolic process 1.1854E-4 2 69 2 6292
    RNA catabolic process 1.5966E-4 2 80 2 6292
    nuclear-transcribed mRNA catabolic process, deadenylation-independent decay 6.3568E-4 2 2 1 6292
    deadenylation-independent decapping of nuclear-transcribed mRNA 6.3568E-4 2 2 1 6292
    mRNA metabolic process 1.1408E-3 2 213 2 6292
    cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
    macromolecule catabolic process 2.1762E-3 2 294 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    catabolic process 6.2027E-3 2 496 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    m7G(5')pppN diphosphatase activity 5.0527E-7 2 5 2 6292
    hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
    pyrophosphatase activity 3.1391E-3 2 353 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle