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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 0.898812078475]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin cortical patch 4.1432E-5 2 41 2 6292
cortical actin cytoskeleton 6.6999E-5 2 52 2 6292
cortical cytoskeleton 6.6999E-5 2 52 2 6292
actin cytoskeleton 1.8038E-4 2 85 2 6292
cell cortex part 2.304E-4 2 96 2 6292
cell cortex 2.974E-4 2 109 2 6292
F-actin capping protein complex 6.3568E-4 2 2 1 6292
cytoskeletal part 1.0156E-3 2 201 2 6292
cytoskeleton 1.1732E-3 2 216 2 6292
actin filament 2.859E-3 2 9 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of actin polymerization or depolymerization 1.5158E-7 2 3 2 6292
protein polymerization 1.5158E-7 2 3 2 6292
regulation of actin cytoskeleton organization 1.5158E-7 2 3 2 6292
regulation of protein polymerization 1.5158E-7 2 3 2 6292
negative regulation of protein polymerization 1.5158E-7 2 3 2 6292
negative regulation of protein complex assembly 1.5158E-7 2 3 2 6292
actin filament polymerization 1.5158E-7 2 3 2 6292
regulation of actin filament polymerization 1.5158E-7 2 3 2 6292
regulation of actin filament length 1.5158E-7 2 3 2 6292
negative regulation of actin filament polymerization 1.5158E-7 2 3 2 6292
regulation of actin filament-based process 1.5158E-7 2 3 2 6292
negative regulation of cytoskeleton organization 1.4147E-6 2 8 2 6292
actin polymerization or depolymerization 1.819E-6 2 9 2 6292
regulation of protein complex assembly 2.779E-6 2 11 2 6292
regulation of cellular component biogenesis 7.7306E-6 2 18 2 6292
regulation of cytoskeleton organization 9.6001E-6 2 20 2 6292
negative regulation of cellular component organization 2.0514E-5 2 29 2 6292
negative regulation of organelle organization 2.0514E-5 2 29 2 6292
regulation of organelle organization 6.6999E-5 2 52 2 6292
cellular protein complex assembly 7.2304E-5 2 54 2 6292
actin filament organization 1.151E-4 2 68 2 6292
regulation of cellular component organization 1.4021E-4 2 75 2 6292
sequestering of actin monomers 3.1786E-4 2 1 1 6292
actin cytoskeleton organization 3.1973E-4 2 113 2 6292
regulation of anatomical structure size 3.2544E-4 2 114 2 6292
regulation of cellular component size 3.2544E-4 2 114 2 6292
actin filament-based process 3.4287E-4 2 117 2 6292
protein complex biogenesis 6.0304E-4 2 155 2 6292
protein complex assembly 6.0304E-4 2 155 2 6292
barbed-end actin filament capping 6.3568E-4 2 2 1 6292
actin filament capping 6.3568E-4 2 2 1 6292
negative regulation of actin filament depolymerization 6.3568E-4 2 2 1 6292
regulation of actin filament depolymerization 6.3568E-4 2 2 1 6292
cellular macromolecular complex assembly 8.3223E-4 2 182 2 6292
actin filament depolymerization 1.2712E-3 2 4 1 6292
cytoskeleton organization 1.3422E-3 2 231 2 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
cellular macromolecular complex subunit organization 1.6882E-3 2 259 2 6292
macromolecular complex assembly 1.9877E-3 2 281 2 6292
negative regulation of protein complex disassembly 2.224E-3 2 7 1 6292
protein depolymerization 3.1764E-3 2 10 1 6292
regulation of protein complex disassembly 3.1764E-3 2 10 1 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
cellular component assembly 3.7349E-3 2 385 2 6292
regulation of biological quality 7.6561E-3 2 551 2 6292
maintenance of protein location 8.248E-3 2 26 1 6292
maintenance of location 8.8811E-3 2 28 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin binding 1.0611E-5 2 21 2 6292
cytoskeletal protein binding 8.6451E-5 2 59 2 6292
actin monomer binding 6.3568E-4 2 2 1 6292
actin filament binding 3.811E-3 2 12 1 6292
protein binding 9.4468E-3 2 612 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle