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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 1.03209985586]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

spliceosomal complex 5.0022E-5 2 45 2 6292
ribonucleoprotein complex 6.6615E-3 2 514 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

generation of catalytic spliceosome for second transesterification step 5.0527E-7 2 5 2 6292
spliceosomal conformational changes to generate catalytic conformation 1.819E-6 2 9 2 6292
ribonucleoprotein complex assembly 2.1151E-4 2 92 2 6292
nuclear mRNA splicing, via spliceosome 2.4511E-4 2 99 2 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 2.5011E-4 2 100 2 6292
RNA splicing, via transesterification reactions 2.8654E-4 2 107 2 6292
RNA splicing 4.3685E-4 2 132 2 6292
mRNA processing 6.1087E-4 2 156 2 6292
cellular macromolecular complex assembly 8.3223E-4 2 182 2 6292
mRNA metabolic process 1.1408E-3 2 213 2 6292
cellular macromolecular complex subunit organization 1.6882E-3 2 259 2 6292
macromolecular complex assembly 1.9877E-3 2 281 2 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
ribonucleoprotein complex biogenesis 3.5243E-3 2 374 2 6292
RNA processing 3.6384E-3 2 380 2 6292
cellular component assembly 3.7349E-3 2 385 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

second spliceosomal transesterification activity 1.0611E-6 2 7 2 6292
ATP-dependent RNA helicase activity 8.8811E-3 2 28 1 6292
RNA-dependent ATPase activity 9.1975E-3 2 29 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle