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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

eukaryotic translation initiation factor 2B complex 7.3127E-17 6 5 5 6292
guanyl-nucleotide exchange factor complex 1.5353E-15 6 7 5 6292
protein complex 3.4445E-5 6 1137 6 6292
macromolecular complex 3.0579E-4 6 1635 6 6292
eukaryotic translation initiation factor 2 complex 2.8585E-3 6 3 1 6292
cytoplasmic part 3.7539E-3 6 2482 6 6292
multi-eIF complex 7.6075E-3 6 8 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of translational initiation 3.3758E-14 6 11 5 6292
translational initiation 6.1016E-14 6 42 6 6292
regulation of translation 3.0408E-10 6 57 5 6292
posttranscriptional regulation of gene expression 4.3182E-10 6 61 5 6292
regulation of cellular protein metabolic process 7.5592E-10 6 68 5 6292
regulation of protein metabolic process 1.1672E-9 6 74 5 6292
translation 4.3855E-8 6 376 6 6292
regulation of gene expression 9.7906E-6 6 445 5 6292
regulation of macromolecule biosynthetic process 1.1051E-5 6 456 5 6292
regulation of cellular biosynthetic process 1.3111E-5 6 472 5 6292
regulation of biosynthetic process 1.3249E-5 6 473 5 6292
regulation of macromolecule metabolic process 1.5465E-5 6 488 5 6292
regulation of primary metabolic process 1.9994E-5 6 514 5 6292
cellular protein metabolic process 2.4449E-5 6 1074 6 6292
regulation of cellular metabolic process 2.4598E-5 6 536 5 6292
regulation of metabolic process 2.7195E-5 6 547 5 6292
protein metabolic process 3.4263E-5 6 1136 6 6292
cellular macromolecule biosynthetic process 4.4618E-5 6 1187 6 6292
macromolecule biosynthetic process 4.5072E-5 6 1189 6 6292
gene expression 7.1216E-5 6 1283 6 6292
regulation of cellular process 1.7215E-4 6 796 5 6292
regulation of biological process 2.0387E-4 6 824 5 6292
cellular biosynthetic process 2.3689E-4 6 1567 6 6292
biosynthetic process 2.7052E-4 6 1602 6 6292
biological regulation 1.333E-3 6 1213 5 6292
cellular macromolecule metabolic process 2.2844E-3 6 2285 6 6292
macromolecule metabolic process 2.6967E-3 6 2349 6 6292
primary metabolic process 9.4808E-3 6 2896 6 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

translation initiation factor activity 3.443E-15 6 27 6 6292
translation factor activity, nucleic acid binding 8.2107E-14 6 44 6 6292
guanyl-nucleotide exchange factor activity 3.6545E-11 6 38 5 6292
GTPase regulator activity 2.2339E-9 6 84 5 6292
nucleoside-triphosphatase regulator activity 4.1865E-9 6 95 5 6292
enzyme regulator activity 2.147E-7 6 207 5 6292
nucleic acid binding 1.3783E-6 6 666 6 6292
binding 7.4967E-5 6 1294 6 6292

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