YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes:	Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size:	16 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
ISA2	mitochondrial intermembrane space mitochondrion	iron ion transport response to drug biotin biosynthetic process	molecular_function
PUF4	cytoplasm	loss of chromatin silencing involved in replicative cell aging protein localization mRNA catabolic process nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	mRNA binding
RPL17A	cytoplasm	translation	structural constituent of ribosome
RPL17B	ribonucleoprotein complex cytoplasm large ribosomal subunit cytosolic large ribosomal subunit ribosome intracellular	translation	structural constituent of ribosome
RPL18A, RPL18B	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	regulation of translation translation	structural constituent of ribosome
RPL29	cytoplasm	translation	structural constituent of ribosome
RPL2A, RPL2B	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	regulation of translation response to drug translation	RNA binding structural constituent of ribosome rRNA binding
RPL3	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	ribosomal large subunit assembly translation	structural constituent of ribosome
RPL32	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translation	structural constituent of ribosome
RPL36A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translation	RNA binding structural constituent of ribosome
RPL42B, RPL42A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	response to antibiotic response to cycloheximide translation	structural constituent of ribosome
RPL4A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translation	structural constituent of ribosome
RPL6A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	ribosomal large subunit assembly translation	RNA binding structural constituent of ribosome
RPS17B	ribonucleoprotein complex cytosolic small ribosomal subunit cytoplasm ribosome intracellular	telomere maintenance ribosomal small subunit assembly translation	structural constituent of ribosome
RPS30B, RPS30A	stress granule ribonucleoprotein complex cytoplasm cytosolic small ribosomal subunit ribosome intracellular	translation	structural constituent of ribosome
YHI9	cellular_component	biological_process	molecular_function

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
cytosolic ribosome	4.2764E-17	16	101	11	6292
cytosolic part	3.7174E-16	16	122	11	6292
cytosolic large ribosomal subunit	3.7936E-15	16	60	9	6292
ribosomal subunit	3.5981E-14	16	183	11	6292
large ribosomal subunit	1.1327E-12	16	110	9	6292
cytosol	4.6826E-12	16	284	11	6292
ribosome	5.8907E-12	16	290	11	6292
ribonucleoprotein complex	2.9227E-9	16	514	11	6292
non-membrane-bounded organelle	2.0406E-6	16	959	11	6292
intracellular non-membrane-bounded organelle	2.0406E-6	16	959	11	6292
macromolecular complex	4.0449E-4	16	1635	11	6292
cytoplasm	1.4044E-3	16	3552	15	6292
organelle part	1.8408E-3	16	2282	12	6292
intracellular organelle part	1.8408E-3	16	2282	12	6292
stress granule	2.5429E-3	16	1	1	6292
cytosolic small ribosomal subunit	4.0408E-3	16	38	2	6292
cytoplasmic part	4.2332E-3	16	2482	12	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
translation	4.8281E-14	16	376	13	6292
cellular macromolecule biosynthetic process	5.5583E-9	16	1187	14	6292
macromolecule biosynthetic process	5.6875E-9	16	1189	14	6292
cellular biosynthetic process	1.0277E-8	16	1567	15	6292
biosynthetic process	1.4238E-8	16	1602	15	6292
gene expression	1.6039E-8	16	1283	14	6292
cellular protein metabolic process	3.3002E-8	16	1074	13	6292
protein metabolic process	6.6515E-8	16	1136	13	6292
cellular macromolecule metabolic process	3.566E-5	16	2285	14	6292
macromolecule metabolic process	5.1061E-5	16	2349	14	6292
cellular metabolic process	1.5217E-4	16	3033	15	6292
metabolic process	2.6858E-4	16	3157	15	6292
ribosomal subunit assembly	3.2659E-4	16	55	3	6292
ribosome assembly	5.1146E-4	16	64	3	6292
organelle assembly	6.382E-4	16	69	3	6292
primary metabolic process	7.3973E-4	16	2896	14	6292
ribonucleoprotein complex assembly	1.476E-3	16	92	3	6292
response to cycloalkane	2.5429E-3	16	1	1	6292
response to organic cyclic substance	2.5429E-3	16	1	1	6292
response to cycloheximide	2.5429E-3	16	1	1	6292
ribosomal large subunit assembly	4.6924E-3	16	41	2	6292
response to antibiotic	7.6106E-3	16	3	1	6292
regulation of translation	8.9193E-3	16	57	2	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
structural constituent of ribosome	2.5689E-17	16	212	13	6292
structural molecule activity	1.2484E-14	16	339	13	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis