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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.559157891378]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
NPL3
  • nucleus
  • cytoplasm
    		•
  • mRNA export from nucleus
  • pseudohyphal growth
    		•
  • poly(A) RNA binding
  • mRNA binding
    		•
    SUB2
  • chromosome, telomeric region
  • nucleus
  • spliceosomal complex
  • transcription export complex
    		•
  • mRNA export from nucleus
  • chromatin silencing at telomere
  • nuclear mRNA splicing, via spliceosome
    		•
  • RNA binding
  • protein binding
  • ATP-dependent RNA helicase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription export complex 1.2712E-3 2 4 1 6292
    chromosome, telomeric region 8.5646E-3 2 27 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mRNA export from nucleus 1.151E-4 2 68 2 6292
    mRNA transport 1.151E-4 2 68 2 6292
    RNA export from nucleus 1.5966E-4 2 80 2 6292
    RNA transport 1.6371E-4 2 81 2 6292
    nucleic acid transport 1.6371E-4 2 81 2 6292
    establishment of RNA localization 1.6371E-4 2 81 2 6292
    RNA localization 2.1151E-4 2 92 2 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 2.304E-4 2 96 2 6292
    nuclear export 2.6542E-4 2 103 2 6292
    nuclear transport 4.2367E-4 2 130 2 6292
    nucleocytoplasmic transport 4.2367E-4 2 130 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    poly-purine tract binding 1.5888E-3 2 5 1 6292
    poly(A) RNA binding 1.5888E-3 2 5 1 6292
    single-stranded RNA binding 1.5888E-3 2 5 1 6292
    RNA binding 3.3934E-3 2 367 2 6292
    ATP-dependent RNA helicase activity 8.8811E-3 2 28 1 6292
    RNA-dependent ATPase activity 9.1975E-3 2 29 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle