From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.578194107585] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
DLD3 |
|
|
|
LEU1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
soluble fraction | 5.2295E-5 | 2 | 46 | 2 | 6292 |
cell fraction | 4.1715E-4 | 2 | 129 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
lactate metabolic process | 1.5888E-3 | 2 | 5 | 1 | 6292 |
leucine biosynthetic process | 1.9064E-3 | 2 | 6 | 1 | 6292 |
leucine metabolic process | 2.5415E-3 | 2 | 8 | 1 | 6292 |
organic acid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
oxoacid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
carboxylic acid metabolic process | 2.793E-3 | 2 | 333 | 2 | 6292 |
cellular ketone metabolic process | 3.0157E-3 | 2 | 346 | 2 | 6292 |
branched chain family amino acid biosynthetic process | 4.7627E-3 | 2 | 15 | 1 | 6292 |
branched chain family amino acid metabolic process | 5.7138E-3 | 2 | 18 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
3-isopropylmalate dehydratase activity | 3.1786E-4 | 2 | 1 | 1 | 6292 |
D-lactate dehydrogenase (cytochrome) activity | 9.5344E-4 | 2 | 3 | 1 | 6292 |
oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor | 1.2712E-3 | 2 | 4 | 1 | 6292 |
lactate dehydrogenase activity | 1.2712E-3 | 2 | 4 | 1 | 6292 |
hydro-lyase activity | 8.5646E-3 | 2 | 27 | 1 | 6292 |