From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.600696036709] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
ARP1 |
|
|
|
MDM1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
intermediate filament | 6.3568E-4 | 2 | 2 | 1 | 6292 |
intermediate filament cytoskeleton | 6.3568E-4 | 2 | 2 | 1 | 6292 |
cytoskeletal part | 1.0156E-3 | 2 | 201 | 2 | 6292 |
cytoskeleton | 1.1732E-3 | 2 | 216 | 2 | 6292 |
dynactin complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
microtubule associated complex | 5.7138E-3 | 2 | 18 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear migration | 9.6001E-6 | 2 | 20 | 2 | 6292 |
nucleus localization | 9.6001E-6 | 2 | 20 | 2 | 6292 |
establishment of nucleus localization | 9.6001E-6 | 2 | 20 | 2 | 6292 |
establishment of organelle localization | 7.5032E-5 | 2 | 55 | 2 | 6292 |
organelle localization | 1.8038E-4 | 2 | 85 | 2 | 6292 |
establishment of spindle localization | 3.1764E-3 | 2 | 10 | 1 | 6292 |
establishment of spindle orientation | 3.1764E-3 | 2 | 10 | 1 | 6292 |
establishment of mitotic spindle localization | 3.1764E-3 | 2 | 10 | 1 | 6292 |
spindle localization | 3.1764E-3 | 2 | 10 | 1 | 6292 |
establishment of mitotic spindle orientation | 3.1764E-3 | 2 | 10 | 1 | 6292 |
establishment of localization in cell | 9.0494E-3 | 2 | 599 | 2 | 6292 |
mitochondrion inheritance | 9.1975E-3 | 2 | 29 | 1 | 6292 |
mitochondrion distribution | 9.1975E-3 | 2 | 29 | 1 | 6292 |
mitochondrion localization | 9.5139E-3 | 2 | 30 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
structural constituent of cytoskeleton | 6.9626E-5 | 2 | 53 | 2 | 6292 |
structural molecule activity | 2.8947E-3 | 2 | 339 | 2 | 6292 |
phosphatidylinositol-3-phosphate binding | 6.0308E-3 | 2 | 19 | 1 | 6292 |