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Protein Overview: T1RK_ECOLI

General Information:
Name(s) found: T1RK_ECOLI [Swiss-Prot]
Description(s) found:
Found 7 descriptions.
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  • Type I restriction enzyme EcoKI R protein (EC 3.1.21.3) (R.EcoKI) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 1188 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLWALNIWTG PHSNGLITMM NKSNFEFLKG VNDFTYAIAC AAENNYPDDP NTTLIKMRMF  60
   61 GEATAKHLGL LLNIPPCENQ HDLLRELGKI AFVDDNILSV FHKLRRIGNQ AVHEYHNDLN 120
  121 DAQMCLRLGF RLAVWYYRLV TKDYDFPVPV FVLPERGENL YHQEVLTLKQ QLEQQVREKA 180
  181 QTQAEVEAQQ QKLVALNGYI AILEGKQQET EAQTQARLAA LEAQLAEKNA ELAKQTEQER 240
  241 KAYHKEITDQ AIKRTLNLSE EESRFLIDAQ LRKAGWQADS KTLRFSKGAR PEPGVNKAIA 300
  301 EWPTGKDETG NQGFADYVLF VGLKPIAVVE AKRNNIDVPA RLNESYRYSK CFDNGFLRET 360
  361 LLEHYSPDEV HEAVPEYETS WQDTSGKQRF KIPFCYSTNG REYRATMKTK SGIWYRDVRD 420
  421 TRNMSKALPE WHRPEELLEM LGSEPQKQNQ WFADNPGMSE LGLRYYQEDA VRAVEKAIVK 480
  481 GQQEILLAMA TGTGKTRTAI AMMFRLIQSQ RFKRILFLVD RRSLGEQALG AFEDTRINGD 540
  541 TFNSIFDIKG LTDKFPEDST KIHVATVQSL VKRTLQSDEP MPVARYDCIV VDEAHRGYIL 600
  601 DKEQTEGELQ FRSQLDYVSA YRRILDHFDA VKIALTATPA LHTVQIFGEP VYRYTYRTAV 660
  661 IDGFLIDQDP PIQIITRNAQ EGVYLSKGEQ VERISPQGEV INDTLEDDQD FEVADFNRGL 720
  721 VIPAFNRAVC NELTNYLDPT GSQKTLVFCV TNAHADMVVE ELRAAFKKKY PQLEHDAIIK 780
  781 ITGDADKDAR KVQTMITRFN KERLPNIVVT VDLLTTGVDI PSICNIVFLR KVRSRILYEQ 840
  841 MKGRATRLCP EVNKTSFKIF DCVDIYSTLE SVDTMRPVVV RPKVELQTLV NEITDSETYK 900
  901 ITEADGRSFA EHSHEQLVAK LQRIIGLATF NRDRSETIDK QVRRLDELCQ DAAGVNFNGF 960
  961 ASRLREKGPH WSAEVFNKLP GFIARLEKLK TDINNLNDAP IFLDIDDEVV SVKSLYGDYD1020
 1021 TPQDFLEAFD SLVQRSPNAQ PALQAVINRP RDLTRKGLVE LQEWFDRQHF EESSLRKAWK1080
 1081 ETRNEDIAAR LIGHIRRAAV GDALKPFEER VDHALTRIKG ENDWSSEQLS WLDRLAQALK1140
 1141 EKVVLDDDVF KTGNFHRRGG KAMLQRTFDD NLDTLLGKFS DYIWDELA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] FFAS03 1.06 Crystal structure of TT1696 from Thermus thermophilus HB8
    2 View Details [141..1035] PSI-BLAST 54.69897 Crystal structure of Escherichia coli transcription-repair coupling factor
    3 View Details [1036..1100] PSI-BLAST 59.69897 Nucleotide excision repair enzyme UvrB
    4 View Details [1101..1188] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity, transferring phosphorus-containing groups
    		•  1.24806580264996 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.19270389706112 bayes_pls_golite062009
  • transferase activity
    		•  0.902981870272937 bayes_pls_golite062009
  • catalytic activity
    		•  0.853948963582441 bayes_pls_golite062009
    2
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.16381244011837 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.13284212711072 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.11265775498161 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.11046854230259 bayes_pls_golite062009
  • hydrolase activity
    		•  1.66122526893602 bayes_pls_golite062009
  • ATPase activity
    		•  1.53315090215319 bayes_pls_golite062009
  • binding
    		•  1.41264401383678 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.1653223755451 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.923452757551011 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.923391844349459 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.920821955769652 bayes_pls_golite062009
  • nucleotide binding
    		•  0.917754212279227 bayes_pls_golite062009
  • helicase activity
    		•  0.895387263223335 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.8104901979223 bayes_pls_golite062009
  • ATP binding
    		•  0.60527666756293 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.573214556107072 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.554530910579109 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.216266069700019 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.156322124775303 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.156322124775303 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0398638249772338 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle