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Protein Overview: NIKA_ECOLI

General Information:
Name(s) found: NIKA_ECOLI [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Nickel-binding periplasmic protein precursor - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 524 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSTLRRTLF ALLACASFIV HAAAPDEITT AWPVNVGPLN PHLYTPNQMF AQSMVYEPLV  60
   61 KYQADGSVIP WLAKSWTHSE DGKTWTFTLR DDVKFSNGEP FDAEAAAENF RAVLDNRQRH 120
  121 AWLELANQIV DVKALSKTEL QITLKSAYYP FLQELALPRP FRFIAPSQFK NHETMNGIKA 180
  181 PIGTGPWILQ ESKLNQYDVF VRNENYWGEK PAIKKITFNV IPDPTTRAVA FETGDIDLLY 240
  241 GNEGLLPLDT FARFSQNPAY HTQLSQPIET VMLALNTAKA PTNELAVREA LNYAVNKKSL 300
  301 IDNALYGTQQ VADTLFAPSV PYANLGLKPS QYDPQKAKAL LEKAGWTLPA GKDIREKNGQ 360
  361 PLRIELSFIG TDALSKSMAE IIQADMRQIG ADVSLIGEEE SSIYARQRDG RFGMIFHRTW 420
  421 GAPYDPHAFL SSMRVPSHAD FQAQQGLADK PLIDKEIGEV LATHDETQRQ ALYRDILTRL 480
  481 HDEAVYLPIS YISMMVVSKP ELGNIPYAPI ATEIPFEQIK PVKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..524] PSI-BLAST 118.0 Crystallographic and spectroscopic evidence for high affinity binding of Fe EDTA (H2O)- to the periplasmic nickel transporter NikA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ATPase activity, coupled to transmembrane movement of substances
    		•  7.32513858490159 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  7.32461921873446 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  7.32461921873446 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  7.30967709770689 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  7.29915074349679 bayes_pls_golite062009
  • oligopeptide transporter activity
    		•  7.2433462247746 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  7.22701734359888 bayes_pls_golite062009
  • peptide transporter activity
    		•  6.65358482101265 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  6.6184830833742 bayes_pls_golite062009
  • ATPase activity
    		•  6.25872881857398 bayes_pls_golite062009
  • dipeptide transporter activity
    		•  6.15818525311031 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  5.90322606085411 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  5.82359353784758 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  5.80191380928519 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  5.80159621701122 bayes_pls_golite062009
  • peptide-transporting ATPase activity
    		•  4.88181218330665 bayes_pls_golite062009
  • oligopeptide-transporting ATPase activity
    		•  4.33503585684315 bayes_pls_golite062009
  • hydrolase activity
    		•  4.03317966718526 bayes_pls_golite062009
  • transporter activity
    		•  3.92658561501282 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.71430307970333 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.34421502810243 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  3.25040168593981 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.16446457499691 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.76254706952599 bayes_pls_golite062009
  • molybdate transmembrane-transporting ATPase activity
    		•  2.58578176144479 bayes_pls_golite062009
  • molybdate ion transmembrane transporter activity
    		•  2.58578176144479 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.84929214408108 bayes_pls_golite062009
  • binding
    		•  1.54172013140566 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  0.88623763826001 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  0.75669016367838 bayes_pls_golite062009
  • polyamine transmembrane transporter activity
    		•  0.74959887541426 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  0.3752347482824 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  0.372828805396439 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.343508026849565 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  0.22884273975653 bayes_pls_golite062009
  • sulfate transmembrane-transporting ATPase activity
    		•  0.0940079640524907 bayes_pls_golite062009
  • polyamine-transporting ATPase activity
    		•  0.0497853931936705 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0237973852493387 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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