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Protein Overview: KUP_ECOLI

General Information:
Name(s) found: KUP_ECOLI [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Low affinity potassium transport system protein kup (Kup system potassium uptake protein) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 622 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTDNKQSLP AITLAAIGVV YGDIGTSPLY TLRECLSGQF GFGVERDAVF GFLSLIFWLL  60
   61 IFVVSIKYLT FVMRADNAGE GGILTLMSLA GRNTSARTTS MLVIMGLIGG SFFYGEVVIT 120
  121 PAISVMSAIE GLEIVAPQLD TWIVPLSIIV LTLLFMIQKH GTAMVGKLFA PIMLTWFLIL 180
  181 AGLGLRSIIA NPEVLHALNP MWAVHFFLEY KTVSFIALGA VVLSITGVEA LYADMGHFGK 240
  241 FPIRLAWFTV VLPSLTLNYF GQGALLLKNP EAIKNPFFLL APDWALIPLL IIAALATVIA 300
  301 SQAVISGVFS LTRQAVRLGY LSPMRIIHTS EMESGQIYIP FVNWMLYVAV VIVIVSFEHS 360
  361 SNLAAAYGIA VTGTMVLTSI LSTTVARQNW HWNKYFVALI LIAFLCVDIP LFTANLDKLL 420
  421 SGGWLPLSLG TVMFIVMTTW KSERFRLLRR MHEHGNSLEA MIASLEKSPP VRVPGTAVYM 480
  481 SRAINVIPFA LMHNLKHNKV LHERVILLTL RTEDAPYVHN VRRVQIEQLS PTFWRVVASY 540
  541 GWRETPNVEE VFHRCGLEGL SCRMMETSFF MSHESLILGK RPWYLRLRGK LYLLLQRNAL 600
  601 RAPDQFEIPP NRVIELGTQV EI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..454] FFAS03 1.21 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
    2 View Details [455..622] Pfam 3.853872 No description for PF02705.7 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  4.88630622071834 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.32521787992483 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.27255146158842 bayes_pls_golite062009
  • transporter activity
    		•  3.46503611631839 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.34431027577801 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.08398439124803 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.98812190037621 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  1.84089435211537 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.37015067735708 bayes_pls_golite062009
  • symporter activity
    		•  1.31198147603118 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  1.31198147603118 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.20549091362469 bayes_pls_golite062009
  • solute:sodium symporter activity
    		•  0.868753445363102 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.716334764204393 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  0.627257208878789 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  0.625686018130389 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  0.455036513774109 bayes_pls_golite062009
  • binding
    		•  0.299468111884938 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.260067997236861 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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