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Protein Overview: GSPE_ECOLI

General Information:
Name(s) found: GSPE_ECOLI [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Probable general secretion pathway protein E (Type II traffic warden ATPase) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 493 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIHSPYPAS WALAQRIGYL YSEGEIIYLA DTPFERLLDI QRQVGQCQTM TSLSQADFEA  60
   61 RLEAVFHQNT GESQQIAQDI DQSVDLLSLS EEMPANEDLL NEDSAAPVIR LINAILSEAI 120
  121 KETASDIHIE TYEKTMSIRF RIDGVLRTIL QPNKKLAALL ISRIKVMARL DIAEKRIPQD 180
  181 GRISLRIGRR NIDVRVSTLP SIYGERAVLR LLDKNSLQLS LNNLGMTAAD KQDLENLIQL 240
  241 PHGIILVTGP TGSGKSTTLY AILSALNTPG RNILTVEDPV EYELEGIGQT QVNTRVDMSF 300
  301 ARGLRAILRQ DPDVVMVGEI RDTETAQIAV QASLTGHLVL STLHTNSASG AVTRLRDMGV 360
  361 ESFLLSSSLA GIIAQRLVRR LCPQCRQFTP VSPQQAQMFK YHQLAVTTIG TPVGCPHCHQ 420
  421 SGYQGRMAIH EMMVVTPELR AAIHENVDEQ ALERLVRQQH KALIKNGLQK VISGDTSWDE 480
  481 VMRVASATLE SEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] PSI-BLAST 4.69897 X-ray structure of the general secretion pathway complex of the N- terminal domain of EpsE and the cytosolic domain of EpsL of Vibrio cholerae
    2 View Details [87..493] PSI-BLAST 124.0 Crystal Structure of Vibrio cholerae putative NTPase EpsE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein transporter activity
    		•  4.96050219760327 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.80249404515499 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.79104521657582 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.72596995524566 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.72417939639501 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.71919653053162 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.71868752128533 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • binding
    		•  1.55526868300981 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • motor activity
    		•  0.87979065815418 bayes_pls_golite062009
  • protein binding
    		•  0.569246647740442 bayes_pls_golite062009
  • catalytic activity
    		•  0.458437698837681 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.373350189511011 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.363151049799385 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • GTP binding
    		•  0.343113158179248 bayes_pls_golite062009
  • GTPase activity
    		•  0.105546189348878 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle