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Protein Overview: SO0859

General Information:
Name(s) found: SO0859 [shew_pnnl_plus_contams_psm.fasta]
Description(s) found:
  • sensory box histidine kinase/response regulator [shew_pnnl_plus_contams_psm.fasta]
    • Organism: Shewanella oneidensis
    Length: 1765 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKSKLRTFR SKILSHIALP LILIMATVYG ITSWFNYLSI EKRLYENLAQ ESSHSASRLQ  60
   61 FLLEHAQANT QGLSDFIGLL ADKDDINNPE KLKTVLTNRI QRNPDFFGSA IAFKPNTFPN 120
  121 KKLFSPYVYR SGSGFNYLDI GADGYDYTDG NWDWWSKAIN QVGGYWSKAY FDEGAGNVLM 180
  181 ITYAVPFGVQ PDYFGVTTVD LALDRLPEQL GIAPSRLVVL DDQGRLIFHS DKEKVLAASS 240
  241 SGWLDKQNIK NIAFATLLND GQAGQASFVD DKGTVYLASV AEVAKLKWRV VVMVPKHELF 300
  301 ASLLDDIASA ILNLSLLTLL LLLTCYIAAK RLTRPLEALE SGILAFGQGK AQELTIPKGA 360
  361 VSEIVTLSET FNQMAALLAE REQAILDSRG NRFARLIDGM SDKSFYCSLD PDGQLAQVSE 420
  421 GVTKVLGIPP ELLKRKYQRL FSANPLNEKN WEYTDLALKG QNVPPHQIEL VDAKGQARRL 480
  481 DVFMQPLVSD TGELMSVEML FTDVTEQFSA AAWSNAVLEA APEAMLIVDQ NGQIVFSNSR 540
  541 CQQLFGYDAK AMLALQIETL LPEELRHLHT GERLDFLREG RDRPMASARH VRALKSDGGE 600
  601 FVAEIALSIL PSDFDGRRQV AASIRDMTQK IMVEQKIRDS ELRFRGLVTN IPGAVYRTRI 660
  661 GEVWVIEYVS DNIAEITGYA ASQFIENRQR TFTSLILEDD RALCNQHIER ALAQQETFEV 720
  721 EYRIRHRDGS IRWVHEKGKA SYSEEGLPLW FDGSIDDVTE SKLAIDEIEA SRQQLTNITE 780
  781 SIPCTVYQLR WVSPTDRSFT FLSGAALAML GLHREELLRD FNIIAERIFD EERPEVISAL 840
  841 AGKSDDQLRW IREFRYRHPN GGIRWMEAGA SGHYADDGSI IWNGYVMDVT ERKSIEEELA 900
  901 VSEAHFKALF DGATIGIVNV DIKGLILDCN YQFCEDMGLS RDELRSTPIF DVLSAQDKDV 960
  961 AKAQFKELVE GKIDHYRGER SFVRPSGEPL WMTVNVSTLL DSQNQFESAV VSMVDMTELK1020
 1021 LLSDELLVAK DEADAASKAK GDFLANMSHE IRTPMNAIIG MSQLCLQTQL DKKQKNYLEK1080
 1081 IERASQSLLS IINDILDFSK IEAGKLDIEN VSFQLDTMLE DLSDMFSERA AQKQIELLFA1140
 1141 VAPNVPRHLL GDPLRLGQVL INLMNNAIKF TERGEVLLSL SLVEQQNDDV VLRFSVRDSG1200
 1201 IGLTQEQQSK LFKSFTQADT STTRKYGGTG LGLAISKQLV ELMGGSIGVE SQLGHGSTFF1260
 1261 FTVKLCISSG QKLFVGQELD GMSILVADDN ATARDIMRTT LESMGFNVDT VRSGDEAIMR1320
 1321 CSQQEYAVAL IDWKMPNLDG IETAKQIKQQ TKNAPRILMV SAHANQDFLT QIEQLGLAGY1380
 1381 ISKPISASRL LDGIMNALGR SGILPVRRHQ DNIAPELLLP LKGKRILLVE DNEMNLEVAT1440
 1441 EFLEQVGIIL SIATNGQIAL DKLAQQSFDL VLMDCQMPVM DGYQATKAIR QRPELAQLPV1500
 1501 IAMTANAMAG DKEMCLRAGM NDHIAKPIEV NLLYQTLLKY LGAPVPSLEN AEFVVNESLN1560
 1561 PLNLDVESVV KWPEHPELDI DRGLQLVQNS KRLYQRIFDR FATSQRNVVD QINKALASNK1620
 1621 REDAVRMAHT LKGLAGNLSS SKLAELARQL ELHLSENADY QVELDQIQIL VASICEAIEK1680
 1681 AKPQFEETST STAEHLPKDA LIAALKQLRQ SLEDADSDAV TQMDALKPQM SALLWQQLSP1740
 1741 ALTMINQYQF DEAVDLIDEV LAKLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] FFAS03 3.71 No description for 2p7jA was found.
    2 View Details [295..410] FFAS03 3.45 M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
    3 View Details [411..498] deduced N/A No confident structure predictions are available.
    4 View Details [499..628] PSI-BLAST 10.154902 Histidine kinase FixL heme domain
    5 View Details [629..771] FFAS03 5.51 No description for 2pr5A was found.
    6 View Details [772..900] PSI-BLAST 8.69897 No description for 2pr5A was found.
    7 View Details [901..1020] PSI-BLAST 9.522879 Histidine kinase FixL heme domain
    8 View Details [1021..1145] PSI-BLAST 42.39794 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    9 View Details [1146..1273] PSI-BLAST 4.69897 No description for 2q2eB was found.
    10 View Details [1274..1639] PSI-BLAST 30.0 Response regulator PleD in complex with c-diGMP
    11 View Details [1640..1765] PSI-BLAST 67.69897 Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • two-component sensor activity
    		•  2.88093868237858 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.86151216540335 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.80671328721504 bayes_pls_golite062009
  • protein kinase activity
    		•  1.74105675066805 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.62873572477094 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.58981311381645 bayes_pls_golite062009
  • kinase activity
    		•  1.5133458700147 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.31628115739307 bayes_pls_golite062009
  • signal transducer activity
    		•  1.10204821596482 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.10204821596482 bayes_pls_golite062009
  • catalytic activity
    		•  0.970922685016416 bayes_pls_golite062009
  • transferase activity
    		•  0.821780694868473 bayes_pls_golite062009
  • binding
    		•  0.704248066961418 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.94020112661684 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.88422125389203 bayes_pls_golite062009
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.70629448457771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.55042643398568 bayes_pls_golite062009
  • DNA binding
    		•  1.54206275665781 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41817054839611 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.31850321187865 bayes_pls_golite062009
  • transcription factor activity
    		•  1.12946889905444 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • potassium channel activity
    		•  0.93265112299626 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.92661046549451 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.926512767264521 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.92204538811959 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.91469735366704 bayes_pls_golite062009
  • ion channel activity
    		•  0.75430461252947 bayes_pls_golite062009
  • cation channel activity
    		•  0.73262554730695 bayes_pls_golite062009
  • gated channel activity
    		•  0.67217953143815 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.650205954115699 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.64202076714636 bayes_pls_golite062009
  • channel activity
    		•  0.64202076714636 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transporter activity
    		•  0.360938622392148 bayes_pls_golite062009
  • catalytic activity
    		•  0.285447488878019 bayes_pls_golite062009
  • transcription factor binding
    		•  0.24293756478811 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.217804199010847 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.94020112661684 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.88422125389203 bayes_pls_golite062009
  • binding
    		•  1.79230776794479 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.70629448457771 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.55042643398568 bayes_pls_golite062009
  • DNA binding
    		•  1.54206275665781 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45691562840107 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.41817054839611 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.31850321187865 bayes_pls_golite062009
  • transcription factor activity
    		•  1.12946889905444 bayes_pls_golite062009
  • protein binding
    		•  1.0133195984081 bayes_pls_golite062009
  • potassium channel activity
    		•  0.93265112299626 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.92661046549451 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.926512767264521 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.92204538811959 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.91469735366704 bayes_pls_golite062009
  • ion channel activity
    		•  0.75430461252947 bayes_pls_golite062009
  • cation channel activity
    		•  0.73262554730695 bayes_pls_golite062009
  • gated channel activity
    		•  0.67217953143815 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.650205954115699 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.64202076714636 bayes_pls_golite062009
  • channel activity
    		•  0.64202076714636 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.58151911764083 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.56538125817883 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.518111391350209 bayes_pls_golite062009
  • signal transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.441034662376355 bayes_pls_golite062009
  • transporter activity
    		•  0.360938622392148 bayes_pls_golite062009
  • catalytic activity
    		•  0.285447488878019 bayes_pls_golite062009
  • transcription factor binding
    		•  0.24293756478811 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.217804199010847 bayes_pls_golite062009
    8 No functions predicted.
    9 No functions predicted.
    10
    Term Confidence Notes
  • two-component response regulator activity
    		•  7.02872640261738 bayes_pls_golite062009
  • signal transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.19396540145756 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.35011582062573 bayes_pls_golite062009
  • two-component sensor activity
    		•  2.32303301074957 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.28838869071567 bayes_pls_golite062009
  • DNA binding
    		•  1.9200042031022 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.7951051076633 bayes_pls_golite062009
  • transcription factor activity
    		•  1.39074763877806 bayes_pls_golite062009
  • binding
    		•  1.22427537074115 bayes_pls_golite062009
  • protein kinase activity
    		•  1.00737355751913 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.811771244977462 bayes_pls_golite062009
  • kinase activity
    		•  0.725824770559857 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.476057209677045 bayes_pls_golite062009
    11
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  1.95073642969863 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.91141407779641 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.9017593265179 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.90014393273511 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  1.84572377553607 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.608578860823 bayes_pls_golite062009
  • transporter activity
    		•  1.55572428045529 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  1.49339466967388 bayes_pls_golite062009
  • ATPase activity
    		•  1.48474288797022 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45919623810582 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.38483976298883 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.37457738689583 bayes_pls_golite062009
  • catalytic activity
    		•  1.37148167194523 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  1.3654237778347 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.32358677895008 bayes_pls_golite062009
  • binding
    		•  1.30574971150356 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.24278046928678 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.22440281711103 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.2014318795788 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.19670408144267 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.17063957238561 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.16918853509059 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.16885789920943 bayes_pls_golite062009
  • hydrolase activity
    		•  1.09839981963412 bayes_pls_golite062009
  • phosphate transmembrane-transporting ATPase activity
    		•  1.05293225786874 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.92950870381166 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.9275205656455 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.91280662021456 bayes_pls_golite062009
  • nucleotide binding
    		•  0.90809801369052 bayes_pls_golite062009
  • ATP binding
    		•  0.59269193555886 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.575892074401446 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.57504013359401 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.54853610492983 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.139527952740579 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.0838665746103899 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0251017125544788 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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