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Protein Overview: CG14722-PA

General Information:
Name(s) found: CG14722-PA / FBpp0081907 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG14722 (CG14722, FBgn0037943). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7567584..7569762. It has the cytological map location 86E17. Based on sequence similarity, it is predicted to have molecular function</span>: apoptotic protease activator activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 498 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: apoptotic protease activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHTHNNFKTP SDEDELDDLD EDMVVGVIAE IEQEVLNESD SDNDEYDLVD MGAPVPDNDG  60
   61 DISYEGNDSS SSDDSFDPNA ADSDSDDSML DEAGGVTAGG ATSAKKRKDD DNPSGSNKQP 120
  121 EATFDLDEDD ETDETVRAMI AAIKKPRSSP PEIKLEDFIT DICFHPDRDI IALATIIGDV 180
  181 HLYEYDNEAN KLLRTIEVHS KACRDVEFTE DGRFLLTCSK DKCVMVTDME TEKLKKLYET 240
  241 AHDDAINTLH VLNENLFASG DDAGTVKLWD LRTKNAIFEL KELEDQITQL TTNEQSKLLL 300
  301 ATSADGYLTT FNISARKMYV QSEPYEEELN CMGVYRGDSK LVVGTSKGRL YTYNWGQFGY 360
  361 HCDMYPGIKS PISLMIPITD RIACVAGEDG NIRACHIAPY RNLGVVGQHN MPIESLDVNA 420
  421 SGELIASSSH NNDVRFWNVK YFEDFGDIKY NEKHNAYKEQ RHNLPSSKCS NASDFFSDLT 480
  481 KENADGDDDP GAGPSNMA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..146] PSI-BLAST 6.0 Surface layer protein
    2 View Details [147..498] PSI-BLAST 81.154902 PAF-AH Holoenzyme: Lis1/Alfa2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • snoRNA binding
    		•  3.44364487903281 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  3.10232773079579 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.89805111479917 bayes_pls_golite062009
    		• 2.40807791198019 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.01595241503145 bayes_pls_golite062009
  • binding
    		•  1.83286470399158 bayes_pls_golite062009
  • RNA binding
    		•  1.50295916950465 bayes_pls_golite062009
  • protein binding
    		•  1.35583841097129 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.25687092973217 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.20712373307552 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.734230328744066 bayes_pls_golite062009
  • DNA binding
    		•  0.711274653406079 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.523052412917759 bayes_pls_golite062009
  • structural molecule activity
    		•  0.254012051644049 bayes_pls_golite062009
  • transcription factor activity
    		•  0.243992994917491 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • ligase activity
    		•  0.20682813699621 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle