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Protein Overview: ADA_RAT

General Information:
Name(s) found: ADA_RAT [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Adenosine deaminase OS=Rattus norvegicus GN=Ada PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 352 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    cytoplasm [UNKNOWN][IDA]
    membrane [UNKNOWN]
    dendrite cytoplasm [IDA]
    external side of plasma membrane [UNKNOWN][IEA]
    cytosol [UNKNOWN]
    cell junction [IEA]
    neuronal cell body [IDA]
    plasma membrane [UNKNOWN][IEA]
    lysosome [UNKNOWN][IEA]
    cell surface [UNKNOWN]
    Biological Process: positive regulation of heart rate [UNKNOWN][IEA]
    positive regulation of T cell differentiation in the thymus [UNKNOWN][IEA]
    T cell activation [UNKNOWN]
    cell adhesion [IEA]
    negative regulation of penile erection [UNKNOWN][IEA]
    placenta development [UNKNOWN][IEA]
    negative regulation of adenosine receptor signaling pathway [UNKNOWN][IEA]
    positive regulation of alpha-beta T cell differentiation [UNKNOWN][IEA]
    nucleotide metabolic process [IEA]
    positive regulation of smooth muscle contraction [UNKNOWN][IEA]
    positive regulation of calcium-mediated signaling [UNKNOWN][IEA]
    lung alveolus development [UNKNOWN][IEA]
    germinal center B cell differentiation [UNKNOWN][IEA]
    positive regulation of T cell activation [UNKNOWN]
    response to hypoxia [UNKNOWN][IEA]
    adenosine metabolic process [IDA][TAS]
    hypoxanthine biosynthetic process [UNKNOWN][IEA]
    embryonic gut development [UNKNOWN][IEA]
    in utero embryonic development [UNKNOWN][IEA]
    positive regulation of germinal center formation [UNKNOWN][IEA]
    negative regulation of thymocyte apoptosis [UNKNOWN][IEA]
    liver development [UNKNOWN][IEA]
    Peyer's patch development [UNKNOWN][IEA]
    regulation of cell-cell adhesion mediated by integrin [UNKNOWN][IEA]
    trophectodermal cell differentiation [UNKNOWN][IEA]
    dATP catabolic process [UNKNOWN][IEA]
    lung development [UNKNOWN]
    purine nucleotide salvage [UNKNOWN][IEA]
    response to vitamin E [IDA]
    negative regulation of inflammatory response [UNKNOWN][IEA]
    deoxyadenosine catabolic process [UNKNOWN][IEA]
    adenosine catabolic process [UNKNOWN][IEA]
    inosine biosynthetic process [UNKNOWN][IEA]
    purine ribonucleoside monophosphate biosynthetic process [IEA]
    response to hydrogen peroxide [IEP]
    aging [IEP]
    negative regulation of leukocyte migration [UNKNOWN][IEA]
    regulation of T cell differentiation [UNKNOWN]
    positive regulation of T cell receptor signaling pathway [UNKNOWN][IEA]
    response to drug [IEP]
    negative regulation of apoptosis [UNKNOWN][IEA]
    positive regulation of T cell differentiation [UNKNOWN]
    regulation of circadian sleep/wake cycle, sleep [IEP]
    xanthine biosynthetic process [UNKNOWN][IEA]
    positive regulation of B cell proliferation [UNKNOWN][IEA]
    negative regulation of mucus secretion [UNKNOWN][IEA]
    negative regulation of mature B cell apoptosis [UNKNOWN][IEA]
    Molecular Function: purine nucleoside binding [IDA]
    zinc ion binding [UNKNOWN][IEA]
    protein binding [UNKNOWN][IEA]
    adenosine deaminase activity [UNKNOWN][IDA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQTPAFNKP KVELHVHLDG AIKPETILYY GKKRGIDLPA DTVEGLRNII GMDKPLSLPD  60
   61 FLAKFDYYMP AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVDPIPWNQA 120
  121 EGDLTPDEVV DLVNQGLQEG EQAFGIKVRS ILCCMRHQPS WSPEVLELCK KYHQKTVVAM 180
  181 DLAGDETIEG SSLFPGHVEA YEGAVKDGIH RTVHAGEVGS AEVVREAVDI LKTERVGHGY 240
  241 HTIEDEALYN RLLKENMHFE VCPWSSYLTG AWNPKTTHAV VRFKDDQANY SLNSDDPLIF 300
  301 KSTVDTDYQM VKKDMGFTEE EFKRLNINAA KSSFLPEDEK KELLERLYKE YQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle