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A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. Any process that modulates the frequency, rate or extent of T cell activation. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. The expansion of a T cell population by cell division. Follows T cell activation. The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. Any process that activates or increases the frequency, rate or extent of T cell activation. Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation. The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: T cell activation
Acc: GO:0042110
Aspect: Biological Process
Desc: The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms:
  • T lymphocyte activation
  • T-lymphocyte activation
  • T-cell activation
Proteins in PDR annotated with:
   This term: 38 [Search]
   Term or descendants: 388 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042110 - T cell activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle