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Protein Overview: ARE2

General Information:
Name(s) found: ARE2 / YNR019W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 642 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: sterol metabolic process [IMPLink to PubMed article]
    Molecular Function: sterol O-acyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKKKDLLEN EQFLRIQKLN AADAGKRQSI TVDDEGELYG LDTSGNSPAN EHTATTITQN  60
   61 HSVVASNGDV AFIPGTATEG NTEIVTEEVI ETDDNMFKTH VKTLSSKEKA RYRQGSSNFI 120
  121 SYFDDMSFEH RPSILDGSVN EPFKTKFVGP TLEKEIRRRE KELMAMRKNL HHRKSSPDAV 180
  181 DSVGKNDGAA PTTVPTAATS ETVVTVETTI ISSNFSGLYV AFWMAIAFGA VKALIDYYYQ 240
  241 HNGSFKDSEI LKFMTTNLFT VASVDLLMYL STYFVVGIQY LCKWGVLKWG TTGWIFTSIY 300
  301 EFLFVIFYMY LTENILKLHW LSKIFLFLHS LVLLMKMHSF AFYNGYLWGI KEELQFSKSA 360
  361 LAKYKDSIND PKVIGALEKS CEFCSFELSS QSLSDQTQKF PNNISAKSFF WFTMFPTLIY 420
  421 QIEYPRTKEI RWSYVLEKIC AIFGTIFLMM IDAQILMYPV AMRALAVRNS EWTGILDRLL 480
  481 KWVGLLVDIV PGFIVMYILD FYLIWDAILN CVAELTRFGD RYFYGDWWNC VSWADFSRIW 540
  541 NIPVHKFLLR HVYHSSMSSF KLNKSQATLM TFFLSSVVHE LAMYVIFKKL RFYLFFFQML 600
  601 QMPLVALTNT KFMRNRTIIG NVIFWLGICM GPSVMCTLYL TF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ARE2 PTC1
    View Details Qiu et al. (2008) ARE1 ARE2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ARE2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] deduced N/A No confident structure predictions are available.
    2 View Details [134..318] MSA 1.024978 View MSA. Confident ab initio structure predictions are available.
    3 View Details [319..397] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [398..642] Pfam 130.823909 No description for PF01800 was found. No confident structure predictions are available.
    5 View Details [488..587] MSA 1.095997 View MSA. No confident structure predictions are available.
    6 View Details [588..642] MSA 1.089996 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle