Protein Overview: MSN2

General Information:
Name(s) found:	MSN2 / YMR037C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|695717\|emb\|CAA88403.1\| Msn2p [Saccharomyces cerevisiae] [NCBI NR] gi\|6323680\|ref\|NP_013751.1\| Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression; [NCBI NR] pir\|\|S39004 finger protein MSN2 - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|462625\|sp\|P33748.1\|MSN2_YEAST RecName: Full=Zinc finger protein MSN2; AltName: Full=Multicopy suppressor of SNF1 protein 2 [NCBI NR] gi\|349595\|gb\|AAA34806.1\| zinc finger protein [NCBI NR] Zinc finger protein MSN2 OS=Saccharomyces cerevisiae GN=MSN2 PE=1 SV=1 [Swiss-Prot] MSN2 Stress responsive regulatory protein [mips] Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression [SGD] MSN2, Chr XIII from 344402-346516, reverse complement [yeast_orfs2] Chr XIII from 344402-346516, reverse complement [yeastorf3.fasta] Chr XIII from 346516-344402, reverse complement [yeastorf5.fasta] (P33748) Zinc finger protein MSN2 (Multicopy suppressor of SNF1 protein 2) [4932.FASTACCERV.txt] MSN2 SGDID:S0004640, Chr XIII from 346516-344402, reverse complement, Verified ORF [yeastflysequest.fasta] Msn2p [Saccharomyces cerevisiae]gi\|695717\|emb\|CAA88403.1\| Msn2p [Saccharomyces cerevisiae]gi\|487101\|pir\|\|S39004 finger protein MSN2 - yeast (Saccharomyces cerevisiae)gi\|462625\|sp\|P33748\|MSN2_YEAST Zinc finger protein MSN2 (Multicopy suppressor of SNF1 [nrdb_11152004_Chlamydomonas] MSN2 SGDID:S000004640, Chr XIII from 346516-344402, reverse complement, Verified ORF, "Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress respon [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] zinc finger protein [nr-271106-contam.fasta] Zinc finger protein MSN2 (Multicopy suppressor of SNF1 protein 2) [nr-271106-contam.fasta] Msn2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression; Msn2p [Saccharomyces cerevis [nr-271106-contam.fasta] MSN2 SGDID:S000004640, Chr XIII from 346516-344402, reverse complement, Verified ORF, "Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Zinc finger protein MSN2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSN2 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] MSN2 SGDID:S000004640, Chr XIII from 346517-344403, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" [yeast-030211-contam.fasta] MSN2 SGDID:S000004640, Chr XIII from 346517-344403, Genome Release 64-2-1, reverse complement, Verified ORF, "Stress-responsive transcriptional activator; activated in stochastic pulses of nuclear localization in response to various stress conditions; binds DNA at stress response elements of responsive genes; relative distribution to nucleus increases upon DNA replication stress" [20141208_orf_trans.fasta] YMR037C SGDID:S000004640, Chr XIII from 346517-344403, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	704 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytosol [IDA]
Biological Process:	response to oxidative stress [IGI] response to hydrostatic pressure [IGI] heat acclimation [IMP] regulation of transcription from RNA polymerase II promoter in response to stress [IMP] response to osmotic stress [IGI] response to freezing [IGI] replicative cell aging [IMP] age-dependent response to oxidative stress involved in chronological cell aging [IMP] response to stress [IMP] cellular response to glucose starvation [IMP]
Molecular Function:	transcription factor activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVDHDFNSE DILFPIESMS SIQYVENNNP NNINNDVIPY SLDIKNTVLD SADLNDIQNQ  60
   61 ETSLNLGLPP LSFDSPLPVT ETIPSTTDNS LHLKADSNKN RDARTIENDS EIKSTNNASG 120
  121 SGANQYTTLT SPYPMNDILY NMNNPLQSPS PSSVPQNPTI NPPINTASNE TNLSPQTSNG 180
  181 NETLISPRAQ QHTSIKDNRL SLPNGANSNL FIDTNPNNLN EKLRNQLNSD TNSYSNSISN 240
  241 SNSNSTGNLN SSYFNSLNID SMLDDYVSSD LLLNDDDDDT NLSRRRFSDV ITNQFPSMTN 300
  301 SRNSISHSLD LWNHPKINPS NRNTNLNITT NSTSSSNASP NTTTMNANAD SNIAGNPKNN 360
  361 DATIDNELTQ ILNEYNMNFN DNLGTSTSGK NKSACPSSFD ANAMTKINPS QQLQQQLNRV 420
  421 QHKQLTSSHN NSSTNMKSFN SDLYSRRQRA SLPIIDDSLS YDLVNKQDED PKNDMLPNSN 480
  481 LSSSQQFIKP SMILSDNASV IAKVATTGLS NDMPFLTEEG EQNANSTPNF DLSITQMNMA 540
  541 PLSPASSSST SLATNHFYHH FPQQGHHTMN SKIGSSLRRR KSAVPLMGTV PLTNQQNNIS 600
  601 SSSVNSTGNG AGVTKERRPS YRRKSMTPSR RSSVVIESTK ELEEKPFHCH ICPKSFKRSE 660
  661 HLKRHVRSVH SNERPFACHI CDKKFSRSDN LSQHIKTHKK HGDI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#03 Alpha Factor Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	MSN2	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..162]	deduced	N/A	No confident structure predictions are available.
2	View Details	[163..351]	MSA	7.63199	View MSA. No confident structure predictions are available.
3	View Details	[352..543]	PSI-BLAST	56.274545	Transcription factor IIIA, TFIIIA
4	View Details	[544..630]	PSI-BLAST	114.06601	Designed zinc finger protein
5	View Details	[631..704]	PSI-BLAST	166.70927	ZIF268

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: MSN2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: