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Protein Overview: VID22

General Information:
Name(s) found: VID22 / YLR373C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 901 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IDALink to PubMed article]
    Biological Process: vacuolar protein catabolic process [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAMDTQVQS AERGLVLPPM NSTVSSATAA TTATNTDTDT DGDRDEERES LAEDGSEWVP  60
   61 AYMLTRDRSR YLGHFLGVDK MLEAVKCKYC GVIIRRQGNS ISMAEASQTH LWSTHKIDPN 120
  121 ANYYSGWTGV EAGSTFMVRP PLKNHQGGSA TTNSIANLLE IDEDFLKRTR EKEMALPLVQ 180
  181 SLAIIIASEN LPLSFVDNTA VRLLINQNAN SLSFIDHDLI LNAIRSIAYN LDRIIQRTAL 240
  241 RNNSDLSLII DKNYLLMDPT DRSNQLSNRL KNQLFEMQKI NFFSLSHSVW NNTISILSIQ 300
  301 YYDDFHSQVK TLPLIIQNLH EYNNDPKLSI PAQLLKISQE LPGLQNTVIS ITLPRSQIVD 360
  361 LLNVMDSQPF FPNTYTNAKN YYHNCIISII NSAILPLFGT PKSADITHPR QSSFSKEPLT 420
  421 LLDSLIDLSN IDISNSIFSR INSFLDDLQS NSWQLDKFRS LCEKFGFEFV CSKFDLSRYS 480
  481 TATVSLQTFL NLRPIIEEYQ SSIQIEKFNE IDFQIIDYLL ITLNSINRIL KFFTSSKSLN 540
  541 FTYVLFAIMS IEKHLLSTLG SLQFQRLIAP FETFLSKIQE FKTILFSDDM NLLAMFLCPA 600
  601 ILFEREVLEY SFHTISLSEI VDKLSTSIFS LLKRFLNLHT IGNVNNSHNT SNHSNMNIHT 660
  661 DNQTNNINNR SGNNSDNNDN EHDNDNDNHS NSNTPASRID IDPTGGENSV LPEQQPQNSN 720
  721 NNLSFGSLSD THHLSDSTIS KEIDSIFLQI IQEDLYDYLS TVNSIVPISY RSYCEQSNFI 780
  781 RDSGRFKKRI ITEDSIIGEL EQPMNFIEEL LDIHVPVCNA FWSQYLDNDA GPIIRILFKI 840
  841 MQCQSSSSIR GEYSFLNDFI PRVHPDLTQE IIKIKLFNDQ FVASKVDYDL DTLQTASQYL 900
  901 P

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) TBF1 VID22 YGR071C
    View Details Krogan NJ, et al. (2006) TBF1 VID22 YGR071C
    View Details Gavin AC, et al. (2006) TBF1 TOR1 VID22

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data VID22 and NOP56 Huh WK, et al. (2003)
    View Data VID22 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..672] MSA 1.002001 View MSA. No confident structure predictions are available.
    2 View Details [673..901] deduced N/A No confident structure predictions are available.
    3 View Details [208..412] deduced N/A No confident structure predictions are available.
    4 View Details [413..647] deduced N/A No confident structure predictions are available.
    5 View Details [648..718] deduced N/A No confident structure predictions are available.
    6 View Details [719..901] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle