YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MET3

General Information:
Name(s) found: MET3 / YJR010W [SGD]
Description(s) found:
Found 31 descriptions.
SHOW ALL
  • ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: sulfate assimilation [TASLink to PubMed article]
    methionine metabolic process [IMPLink to PubMed article]
    Molecular Function: sulfate adenylyltransferase (ATP) activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAPHGGILQ DLIARDALKK NELLSEAQSS DILVWNLTPR QLCDIELILN GGFSPLTGFL  60
   61 NENDYSSVVT DSRLADGTLW TIPITLDVDE AFANQIKPDT RIALFQDDEI PIAILTVQDV 120
  121 YKPNKTIEAE KVFRGDPEHP AISYLFNVAG DYYVGGSLEA IQLPQHYDYP GLRKTPAQLR 180
  181 LEFQSRQWDR VVAFQTRNPM HRAHRELTVR AAREANAKVL IHPVVGLTKP GDIDHHTRVR 240
  241 VYQEIIKRYP NGIAFLSLLP LAMRMSGDRE AVWHAIIRKN YGASHFIVGR DHAGPGKNSK 300
  301 GVDFYGPYDA QELVESYKHE LDIEVVPFRM VTYLPDEDRY APIDQIDTTK TRTLNISGTE 360
  361 LRRRLRVGGE IPEWFSYPEV VKILRESNPP RPKQGFSIVL GNSLTVSREQ LSIALLSTFL 420
  421 QFGGGRYYKI FEHNNKTELL SLIQDFIGSG SGLIIPNQWE DDKDSVVGKQ NVYLLDTSSS 480
  481 ADIQLESADE PISHIVQKVV LFLEDNGFFV F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MET3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] PSI-BLAST 11000.0 ATP sulfurylase N-terminal domain; ATP sulfurylase central domain; ATP sulfurylase C-terminal domain
    2 View Details [167..330] PSI-BLAST 11000.0 ATP sulfurylase N-terminal domain; ATP sulfurylase central domain; ATP sulfurylase C-terminal domain
    3 View Details [331..389] PSI-BLAST 11000.0 ATP sulfurylase N-terminal domain; ATP sulfurylase central domain; ATP sulfurylase C-terminal domain
    4 View Details [390..511] PSI-BLAST 11000.0 ATP sulfurylase N-terminal domain; ATP sulfurylase central domain; ATP sulfurylase C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  3.92128383038213 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  3.92128383038213 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  3.90993291504728 bayes_pls_golite062009
  • binding
    		•  1.78987673253351 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  1.10341596187455 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  1.04188732284751 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.831762535895849 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.428373955572763 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.424644011903671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.424583288440993 bayes_pls_golite062009
  • nucleotide binding
    		•  0.422354428195324 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  0.366166475448387 bayes_pls_golite062009
  • adenylyltransferase activity
    		•  0.19674866587635 bayes_pls_golite062009
  • DNA binding
    		•  0.143403729737365 bayes_pls_golite062009
  • sulfate adenylyltransferase activity
    		•  0.131596240193754 bayes_pls_golite062009
  • sulfate adenylyltransferase (ATP) activity
    		•  0.118324944285084 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.0927746101202402 bayes_pls_golite062009
  • ATP binding
    		•  0.04834397972685 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.0149501427627318 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0147430141176288 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.00365326483311895 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle