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Protein Overview: SHO1

General Information:
Name(s) found: SHO1 / YER118C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 367 amino acids

    Gene Ontology:
    Cellular Component: mating projection tip [IDALink to PubMed article]
    plasma membrane [ISSLink to PubMed article]
    Biological Process: pseudohyphal growth [IMPLink to PubMed article]
    osmosensory signaling pathway via Sho1 osmosensor [TASLink to PubMed article]
    Molecular Function: osmosensor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISSKIRPT PRKPSRMATD HSFKMKKFYA DPFAISSISL AIVSWVIAIG GSISSASTNE  60
   61 SFPRFTWWGI VYQFLIICSL MLFYCFDLVD HYRIFITTSI AVAFVYNTNS ATNLVYADGP 120
  121 KKAAASAGVI LLSIINLIWI LYYGGDNASP TNRWIDSFSI KGIRPSPLEN SLHRARRRGN 180
  181 RNTTPYQNNV YNDAIRDSGY ATQFDGYPQQ QPSHTNYVSS TALAGFENTQ PNTSEAVNLH 240
  241 LNTLQQRINS ASNAKETNDN SNNQTNTNIG NTFDTDFSNG NTETTMGDTL GLYSDIGDDN 300
  301 FIYKAKALYP YDADDDDAYE ISFEQNEILQ VSDIEGRWWK ARRANGETGI IPSNYVQLID 360
  361 GPEEMHR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CDC11 CDC24 CDC42 RHO1 SHO1 SLG1 SLN1 STE4 STE5 WSC2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SST2 SHO1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SHO1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..253] deduced N/A No confident structure predictions are available.
    2 View Details [254..367] PSI-BLAST 76.38764 Fyn proto-oncogene tyrosine kinase, SH3 domain; Tyrosine kinase Fyn

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.42916850671495 bayes_pls_golite062009
  • protein binding
    		•  2.08632303609243 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.69497236763657 bayes_pls_golite062009
  • signal transducer activity
    		•  1.34867629228264 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.34867629228264 bayes_pls_golite062009
  • actin binding
    		•  0.75725452085414 bayes_pls_golite062009
  • receptor binding
    		•  0.351326788023913 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle