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Protein Overview: OCA4

General Information:
Name(s) found: OCA4 / YCR095C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 362 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVPPANFGI AEEGIYRCSK VETLNLSFLE TLNLKTAIFI GGQEPSKFFK DFFTRSSIKW  60
   61 IVLRMSDFSA AAVPVKSSSV SNANLYSNNN STLSLQEEKK KSTANGSQNS TTGDPVIQEE 120
  121 LAYHLTDNDD LMLIKSTCLK RTFKTLLNVD NYNVLLVDKT ALVIGILRKI QKWNIASIIN 180
  181 EYRLFSGKNR NYFAETFLEI INIEIEQEKD NKTIVDNKAK KLPLENNRTH SIEYKANSGK 240
  241 LIRVNEDDLC REPEVPQRLL TLINQIETKV KNNKVLQVSG VLGDDLKKTS SDLGIFGHRY 300
  301 RLAFNKKENG DYGYYKARGK DNVKIRIPCD SELPDWFRFQ RDLWEKENVP EEHHFYREHI 360
  361 FT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) OCA1 OCA4 OCA5 SIW14
    View Details Krogan NJ, et al. (2006) OCA4 OCA5 REC8
    View Details Gavin AC, et al. (2006) OCA1 OCA4 OCA5 SIW14

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data OCA4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..226] ORFEUS 9.43 VH1-related dual-specificity phosphatase, VHR
    2 View Details [227..362] MSA 1.002949 View MSA. No confident structure predictions are available.
    3 View Details [217..362] MSA 1.005947 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  0.358519802008252 bayes_pls_golite062009
  • phosphatase activity
    		•  0.298546457607955 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.286217525019196 bayes_pls_golite062009
  • catalytic activity
    		•  0.231822394832085 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.200316594632455 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.121593189497382 bayes_pls_golite062009
  • binding
    		•  0.0364808517837579 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle