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View Structure Prediction Details

Protein: OCA4
Organism: Saccharomyces cerevisiae
Length: 362 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OCA4.

Description E-value Query
Range
Subject
Range
OCA4 - Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a mode...
gi|207347215 - gi|207347215|gb|EDZ73468.1| YCR095Cp-like protein [Saccharomyces cerevisiae AWRI1631]
OCA4_YEAST - Protein OCA4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OCA4 PE=1 SV=1
gi|190406511 - gi|190406511|gb|EDV09778.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
0.0 [1..362] [1..362]
gi|5815156 - gi|5815156|gb|AAD52574.1|AF170312_1 unknown protein [Saccharomyces kluyveri]
4.0E-51 [253..361] [4..108]
gi|15810022, gi|... - gi|26452426|dbj|BAC43298.1| unknown protein [Arabidopsis thaliana], gi|21555065|gb|AAM63767.1| conta...
7.0E-4 [134..203] [102..176]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.003 [134..204] [25..100]

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Predicted Domain #1
Region A:
Residues: [1-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVPPANFGI AEEGIYRCSK VETLNLSFLE TLNLKTAIFI GGQEPSKFFK DFFTRSSIKW  60
   61 IVLRMSDFSA AAVPVKSSSV SNANLYSNNN STLSLQEEKK KSTANGSQNS TTGDPVIQEE 120
  121 LAYHLTDNDD LMLIKSTCLK RTFKTLLNVD NYNVLLVDKT ALVIGILRKI QKWNIASIIN 180
  181 EYRLFSGKNR NYFAETFLEI INIEIEQEKD NKTIVDNKAK KLPLEN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.43
Match: 1vhrA
Description: VH1-related dual-specificity phosphatase, VHR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 0.358519802008252 bayes_pls_golite062009
phosphatase activity 0.298546457607955 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.286217525019196 bayes_pls_golite062009
catalytic activity 0.231822394832085 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.200316594632455 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.121593189497382 bayes_pls_golite062009
binding 0.0364808517837579 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [227-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRTHSIEYKA NSGKLIRVNE DDLCREPEVP QRLLTLINQI ETKVKNNKVL QVSGVLGDDL  60
   61 KKTSSDLGIF GHRYRLAFNK KENGDYGYYK ARGKDNVKIR IPCDSELPDW FRFQRDLWEK 120
  121 ENVPEEHHFY REHIFT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [217-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKAKKLPLEN NRTHSIEYKA NSGKLIRVNE DDLCREPEVP QRLLTLINQI ETKVKNNKVL  60
   61 QVSGVLGDDL KKTSSDLGIF GHRYRLAFNK KENGDYGYYK ARGKDNVKIR IPCDSELPDW 120
  121 FRFQRDLWEK ENVPEEHHFY REHIFT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle