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Protein Overview: CSN10_YEAST

General Information:
Name(s) found: CSN10_YEAST [Swiss-Prot]
Description(s) found:
  • COP9 signalosome complex subunit 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRI2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 645 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEDNNYDD FMLSDDEGME SIEMEEETDD EDKQNIEINE DNSQDDQDRG AARHKQHEQG  60
   61 TFEKHDRVED ICERIFEQGQ ALKEDERYKE ARDLFLKIYY KEEFSSDESI ERLMTWKFKS 120
  121 LIEILRLRAL QLYFQKNGAQ DLVLQILEDT ATMSVFLQRI DFQIDGNIFE LLSDTFEVLA 180
  181 PKWERVFLFD IEKVDRENMI CKIDFQKNFM DQFQWILRKP GKDCKLQNLQ RIIRKKIFIA 240
  241 VVWYQRLTMG NVFTPEISSQ IEILVKDNEC SSFEENNDLE SVSMLLQYYI LEYMNTARIN 300
  301 NRRLFKKCID FFEMLISKSL TFSQESGLMV ILYTSKIVFI LDSDSENDLS FALMRYYDRK 360
  361 EELKNMFLYI LKHLEEMGKL RERDITSLFH KFILSGFIFT SMILEAISTD KINPFGFEQV 420
  421 KIALGSPIVN VLEDVYRCFA QLELRQLNAS ISLIPELSVV LSGIIQDIYY LAQTLKLWRK 480
  481 IARLYSCISI SDIISMLQIS DDNEMTRDDL LTILMRSIMK NRSVVYFKLD LTSDLVYFGD 540
  541 ENKVMLPRCS KEEFRLMISP KDEETTEKAR LIDFEYVNDV AIYNNPTRIR TKSSKEFFNT 600
  601 LRKSRETVKL PRVSNQSNED TFLPSYMKFS NKYLELCKLA SNNLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..275] deduced N/A No confident structure predictions are available.
    2 View Details [276..560] ORFEUS 8.19 Hemolysin E (HlyE, ClyA, SheA)
    3 View Details [561..645] deduced N/A No confident structure predictions are available.
    4 View Details [414..559] FFAS03 1.38 Solution structure of the PCI domain
    5 View Details [560..645] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  3.45730892915196 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • DNA binding
    		•  3.14200456972385 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.10521633426493 bayes_pls_golite062009
  • transcription factor activity
    		•  2.53044123488453 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.13838000453063 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.28416365596732 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.21263034180893 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.12766532785895 bayes_pls_golite062009
  • transcription activator activity
    		•  1.04520012516585 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.761838897494019 bayes_pls_golite062009
  • protein binding
    		•  0.726445167461826 bayes_pls_golite062009
  • transcription factor binding
    		•  0.534573074451495 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.49516964123412 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.224432853777564 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle