YRC Public Data Repository - Protein Structure Prediction

Protein:	RECN_ECOLI
Organism:	Escherichia coli
Length:	553 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RECN_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|115350691, gi... - gi\|74017086\|ref\|ZP_00687711.1\| DNA repair protein RecN [Burkholderia ambifaria AMMD], gi\|72610557\|gb...	330.0	[0..1]	[553..1]
gi\|119774163, gi... - gi\|68546856\|ref\|ZP_00586400.1\| DNA repair protein RecN [Shewanella amazonensis SB2B], gi\|68515445\|gb...	329.0	[0..1]	[553..1]
gi\|24349692, gi\|... - gi\|24374968\|ref\|NP_719011.1\| recombination and repair protein [Shewanella oneidensis MR-1], gi\|24349... SO3462 - DNA repair protein RecN	327.0	[0..1]	[552..1]
gi\|84360836, gi\|... - gi\|84360836\|ref\|ZP_00985524.1\| COG0497: ATPase involved in DNA repair [Burkholderia dolosa AUO158], ...	326.0	[0..1]	[553..1]
gi\|114333514, gi... - gi\|69954011\|ref\|ZP_00640882.1\| DNA repair protein RecN [Shewanella frigidimarina NCIMB 400], gi\|6916...	325.0	[0..1]	[552..1]
gi\|78506491, gi\|... - gi\|78685806\|ref\|ZP_00850581.1\| DNA repair protein RecN [Shewanella sp. ANA-3], gi\|78506491\|gb\|EAP200...	323.0	[0..1]	[552..1]
gi\|113888118, gi... - gi\|114046676\|ref\|YP_737226.1\| recombination and repair protein [Shewanella sp. MR-7], gi\|113888118\|g...	323.0	[0..1]	[552..1]
gi\|134137973, gi... - gi\|67547624\|ref\|ZP_00425525.1\| DNA repair protein RecN [Burkholderia vietnamiensis G4], gi\|67531059\|...	322.0	[0..1]	[553..1]
gi\|45440885, gi\|... - gi\|45440885\|ref\|NP_992424.1\| recombination and repair protein [Yersinia pestis biovar Microtus str. ... gi\|21959992, gi\|... - gi\|22126951\|ref\|NP_670374.1\| recombination and repair protein [Yersinia pestis KIM], gi\|21959992\|gb\|...	322.0	[0..1]	[553..37]
gi\|82404450, gi\|... - gi\|82497527\|ref\|ZP_00883060.1\| DNA repair protein RecN [Shewanella sp. MR-4], gi\|82404450\|gb\|EAP4513...	321.0	[0..1]	[552..1]

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Predicted Domain #1

Region A:
Residues: [1-157]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAQLTISNF AIVRELEIDF HSGMTVITGE TGAGKSIAID ALGLCLGGRA EADMVRTGAA  60
   61 RADLCARFSL KDTPAALRWL EENQLEDGHE CLLRRVISSD GRSRGFINGT AVPLSQLREL 120
  121 GQLLIQIHGQ HAHQLLTKPE HQKFLLDGYA NETSLLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.69897
Match:	1xewX
Description:	Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphatase activity	1.5002869400376	bayes_pls_golite062009
pyrophosphatase activity	1.49611313354225	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.47468810672455	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.47371190790284	bayes_pls_golite062009
binding	1.41264401383678	bayes_pls_golite062009
hydrolase activity	1.29419296935491	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
ATPase activity	0.844502974582959	bayes_pls_golite062009
DNA-dependent ATPase activity	0.510757066819002	bayes_pls_golite062009
helicase activity	0.51056840156051	bayes_pls_golite062009
nucleic acid binding	0.216266069700019	bayes_pls_golite062009
DNA helicase activity	0.148854929640752	bayes_pls_golite062009
nucleotide binding	0.114848452385726	bayes_pls_golite062009
purine nucleotide binding	0.10713474095071	bayes_pls_golite062009
purine ribonucleotide binding	0.0916519414118148	bayes_pls_golite062009
ribonucleotide binding	0.0915913646217636	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [158-421]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EMTARYQLWH QSCRDLAHHQ QLSQERAARA ELLQYQLKEL NEFNPQPGEF EQIDEEYKRL  60
   61 ANSGQLLTTS QNALALMADG EDANLQSQLY TAKQLVSELI GMDSKLSGVL DMLEEATIQI 120
  121 AEASDELRHY CDRLDLDPNR LFELEQRISK QISLARKHHV SPEALPQYYQ SLLEEQQQLD 180
  181 DQADSQETLA LAVTKHHQQA LEIARALHQQ RQQYAEELAQ LITDSMHALS MPHGQFTIDV 240
  241 KFDEHHLGAD GADRIEFRVT TNPG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.045757
Match:	2i1jA
Description:	No description for 2i1jA was found.

Predicted Domain #3

Region A:
Residues: [422-553]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPMQPIAKVA SGGELSRIAL AIQVITARKM ETPALIFDEV DVGISGPTAA VVGKLLRQLG  60
   61 ESTQVMCVTH LPQVAGCGHQ HYFVSKETDG AMTETHMQSL NKKARLQELA RLLGGSEVTR 120
  121 NTLANAKELL AA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.69897
Match:	2iw3A
Description:	No description for 2iw3A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: