YRC Public Data Repository - Protein Structure Prediction

Protein:	OPPA_ECOLI
Organism:	Escherichia coli
Length:	543 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OPPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|77972677 - gi\|77972677\|ref\|ZP_00828237.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	528.0	[0..1]	[543..1]
gi\|26247572, gi\|... - gi\|26247572\|ref\|NP_753612.1\| periplasmic oligopeptide-binding protein precursor [Escherichia coli CF...	525.0	[0..1]	[543..25]
gi\|115512582, gi... - gi\|117623458\|ref\|YP_852371.1\| periplasmic oligopeptide-binding protein precursor [Escherichia coli A... gi\|91072040, gi\|... - gi\|91210466\|ref\|YP_540452.1\| periplasmic oligopeptide-binding protein precursor [Escherichia coli UT... gi\|226899964, gi... - gi\|237705207\|ref\|ZP_04535688.1\| periplasmic oligopeptide-binding protein [Escherichia sp. 3_2_53FAA]...	524.0	[0..1]	[543..25]
gi\|148876390, gi... - gi\|153828148\|ref\|ZP_01980815.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote... tr\|A2PTK6\|A2PTK6... - Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OS=Vibrio cholerae MZO-3 GN=o... gi\|254225487, gi... - gi\|75820574\|ref\|ZP_00750618.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|153802139, gi... - gi\|153802139\|ref\|ZP_01956725.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote...	524.0	[0..2]	[543..3]
gi\|75830269, gi\|... - gi\|75830269\|ref\|ZP_00759550.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|121587071, gi... - gi\|121587071\|ref\|ZP_01676848.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote... gi\|146315274, gi... - gi\|75826392\|ref\|ZP_00755827.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|153816918, gi... - gi\|153816918\|ref\|ZP_01969585.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote... gi\|75817294, gi\|... - gi\|75817294\|ref\|ZP_00747746.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|153821878, gi... - gi\|229511017\|ref\|ZP_04400496.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding protei... gi\|227009152, gi... - gi\|227081264\|ref\|YP_002809815.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prot... gi\|229357536, gi... - gi\|229505313\|ref\|ZP_04394823.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding protei... gi\|229344853, gi... - gi\|229518138\|ref\|ZP_04407582.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding protei... gi\|229370987, gi... - gi\|229608332\|ref\|YP_002878980.1\| oligopeptide ABC transporter periplasmic oligopeptide-binding prote... gi\|9655560, gi\|1... - gi\|9655560\|gb\|AAF94250.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [Vi... gi\|11277225 - pir\|\|B82242 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein VC1091 [imported]... gi\|254291515, gi... - gi\|254291515\|ref\|ZP_04962306.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote...	523.0	[0..2]	[543..3]
gi\|110343064, gi... - gi\|110641472\|ref\|YP_669202.1\| periplasmic oligopeptide-binding protein precursor [Escherichia coli 5... gi\|191171010, gi... - gi\|191171010\|ref\|ZP_03032561.1\| oligopeptide ABC transporter, periplasmic oligopeptide-binding prote...	523.0	[0..1]	[543..16]
gi\|83587381 - gi\|83587381\|ref\|ZP_00926009.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|215264549, gi... - gi\|215486477\|ref\|YP_002328908.1\| oligopeptide transporter subunit OppA [Escherichia coli O127:H6 str... gi\|157157312, gi... - gi\|75190293\|ref\|ZP_00703560.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|209918482, gi... - gi\|209918482\|ref\|YP_002292566.1\| oligopeptide ABC transporter substrate binding component [Escherich... gi\|157066428, gi... - gi\|75195392\|ref\|ZP_00705462.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|218558171, gi... - gi\|218558171\|ref\|YP_002391084.1\| oligopeptide transporter subunit ; periplasmic-binding component of... gi\|191166636, gi... - gi\|75230199\|ref\|ZP_00716700.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|218360562, gi... - gi\|218553794\|ref\|YP_002386707.1\| oligopeptide transporter subunit ; periplasmic-binding component of... gi\|75235249 - gi\|75235249\|ref\|ZP_00719486.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|82544304, gi\|... - gi\|82544304\|ref\|YP_408251.1\| oligopeptide transport periplasmic binding protein [Shigella boydii Sb2... gi\|242377020, gi... - gi\|251784747\|ref\|YP_002999051.1\| hypothetical protein B21_01227 [Escherichia coli BL21], gi\|24237702... gi\|253973223, gi... - gi\|254161322\|ref\|YP_003044430.1\| oligopeptide transporter subunit [Escherichia coli B str. REL606], ... gi\|254288130, gi... - gi\|254288130\|ref\|YP_003053878.1\| oligopeptide transporter subunit [Escherichia coli BL21(DE3)], gi\|2... gi\|254592113, gi... - gi\|254792713\|ref\|YP_003077550.1\| oligopeptide transporter subunit, periplasmic-binding component of ... gi\|15830997, gi\|... - gi\|15830997\|ref\|NP_309770.1\| oligopeptide transport periplasmic binding protein [Escherichia coli O1... gi\|15830997, gi\|... - gi\|15830997\|ref\|NP_309770.1\| oligopeptide transport periplasmic binding protein [Escherichia coli O1... gi\|209772272, gi... - pir\|\|G90846 hypothetical protein ECs1743 [imported] - Escherichia coli (strain O157:H7, substrain R...	523.0	[0..1]	[543..1]
gi\|75242043 - gi\|75242043\|ref\|ZP_00725837.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	523.0	[0..1]	[543..1]
gi\|75515144, gi\|... - gi\|75515144\|ref\|ZP_00737348.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	523.0	[0..1]	[543..1]
gi\|75257146 - gi\|75257146\|ref\|ZP_00728682.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen... gi\|75212674 - gi\|75212674\|ref\|ZP_00712672.1\| COG4166: ABC-type oligopeptide transport system, periplasmic componen...	523.0	[0..1]	[543..1]

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Predicted Domain #1

Region A:
Residues: [1-543]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNITKRSLV AAGVLAALMA GNVALAADVP AGVTLAEKQT LVRNNGSEVQ SLDPHKIEGV  60
   61 PESNISRDLF EGLLVSDLDG HPAPGVAESW DNKDAKVWTF HLRKDAKWSD GTPVTAQDFV 120
  121 YSWQRSVDPN TASPYASYLQ YGHIAGIDEI LEGKKPITDL GVKAIDDHTL EVTLSEPVPY 180
  181 FYKLLVHPST SPVPKAAIEK FGEKWTQPGN IVTNGAYTLK DWVVNERIVL ERSPTYWNNA 240
  241 KTVINQVTYL PIASEVTDVN RYRSGEIDMT NNSMPIELFQ KLKKEIPDEV HVDPYLCTYY 300
  301 YEINNQKPPF NDVRVRTALK LGMDRDIIVN KVKAQGNMPA YGYTPPYTDG AKLTQPEWFG 360
  361 WSQEKRNEEA KKLLAEAGYT ADKPLTINLL YNTSDLHKKL AIAASSLWKK NIGVNVKLVN 420
  421 QEWKTFLDTR HQGTFDVARA GWCADYNEPT SFLNTMLSNS SMNTAHYKSP AFDSIMAETL 480
  481 KVTDEAQRTA LYTKAEQQLD KDSAIVPVYY YVNARLVKPW VGGYTGKDPL DNTYTRNMYI 540
  541 VKH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	142.0
Match:	1b05A
Description:	Oligo-peptide binding protein (OPPA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ATPase activity, coupled to transmembrane movement of substances	7.32513858490159	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	7.32461921873446	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	7.32461921873446	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	7.30967709770689	bayes_pls_golite062009
primary active transmembrane transporter activity	7.29915074349679	bayes_pls_golite062009
oligopeptide transporter activity	7.2433462247746	bayes_pls_golite062009
active transmembrane transporter activity	7.22701734359888	bayes_pls_golite062009
peptide transporter activity	6.65358482101265	bayes_pls_golite062009
ATPase activity, coupled	6.6184830833742	bayes_pls_golite062009
ATPase activity	6.25872881857398	bayes_pls_golite062009
dipeptide transporter activity	6.15818525311031	bayes_pls_golite062009
nucleoside-triphosphatase activity	5.90322606085411	bayes_pls_golite062009
pyrophosphatase activity	5.82359353784758	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	5.80191380928519	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	5.80159621701122	bayes_pls_golite062009
peptide-transporting ATPase activity	4.88181218330665	bayes_pls_golite062009
oligopeptide-transporting ATPase activity	4.33503585684315	bayes_pls_golite062009
hydrolase activity	4.03317966718526	bayes_pls_golite062009
transporter activity	3.92658561501282	bayes_pls_golite062009
transmembrane transporter activity	3.71430307970333	bayes_pls_golite062009
substrate-specific transporter activity	3.34421502810243	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	3.25040168593981	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	3.16446457499691	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.76254706952599	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	2.58578176144479	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	2.58578176144479	bayes_pls_golite062009
ion transmembrane transporter activity	1.84929214408108	bayes_pls_golite062009
binding	1.54172013140566	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.88623763826001	bayes_pls_golite062009
anion transmembrane transporter activity	0.75669016367838	bayes_pls_golite062009
polyamine transmembrane transporter activity	0.74959887541426	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.3752347482824	bayes_pls_golite062009
amine transmembrane transporter activity	0.372828805396439	bayes_pls_golite062009
cation transmembrane transporter activity	0.343508026849565	bayes_pls_golite062009
amine-transporting ATPase activity	0.22884273975653	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	0.0940079640524907	bayes_pls_golite062009
polyamine-transporting ATPase activity	0.0497853931936705	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0237973852493387	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: