YRC Public Data Repository - Protein Structure Prediction

Protein:	3MG1_ECOLI
Organism:	Escherichia coli
Length:	187 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for 3MG1_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|26110618, gi\|... - gi\|26250189\|ref\|NP_756229.1\| DNA-3-methyladenine glycosylase I [Escherichia coli CFT073], gi\|2611061...	321.0	[0..1]	[187..56]
gi\|115514957, gi... - gi\|117625833\|ref\|YP_859156.1\| 3-methyl-adenine DNA glycosylase I, constitutive [Escherichia coli APE... gi\|237703317, gi... - gi\|237703317\|ref\|ZP_04533798.1\| DNA-3-methyladenine glycosylase I [Escherichia sp. 3_2_53FAA], gi\|22... gi\|91213062, gi\|... - gi\|91213062\|ref\|YP_543048.1\| DNA-3-methyladenine glycosylase I [Escherichia coli UTI89], gi\|91074636...	320.0	[0..1]	[187..56]
gi\|81247325, gi\|... - gi\|82545914\|ref\|YP_409861.1\| 3-methyl-adenine DNA glycosylase I [Shigella boydii Sb227], gi\|81247325... gi\|218372300, gi... - gi\|218702314\|ref\|YP_002409943.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli IAI39], gi\|218...	320.0	[0..1]	[187..1]
gi\|191170471, gi... - gi\|75242660\|ref\|ZP_00726404.1\| COG2818: 3-methyladenine DNA glycosylase [Escherichia coli F11], gi\|1... gi\|162138343 - gi\|162138343\|ref\|YP_543048.2\| 3-methyl-adenine DNA glycosylase I [Escherichia coli UTI89] gi\|162317567 - gi\|162317567\|ref\|YP_859156.2\| 3-methyl-adenine DNA glycosylase I [Escherichia coli APEC O1] gi\|218560626, gi... - gi\|218560626\|ref\|YP_002393539.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli S88], gi\|21836...	320.0	[0..1]	[187..1]
gi\|194420488, gi... - gi\|83571578\|ref\|ZP_00923018.1\| COG2818: 3-methyladenine DNA glycosylase [Shigella dysenteriae 1012],...	319.0	[0..1]	[187..1]
gi\|31615689, gi\|... - gi\|39654450\|pdb\|1P7M\|A Chain A, Solution Structure And Base Perturbation Studies Reveal A Novel Mode... gi\|194425383, gi... - gi\|83588597\|ref\|ZP_00927221.1\| COG2818: 3-methyladenine DNA glycosylase [Escherichia coli 101-1], gi... gi\|251786793, gi... - gi\|251786793\|ref\|YP_003001097.1\| hypothetical protein B21_03350 [Escherichia coli BL21], gi\|24237906... gi\|254290222, gi... - gi\|254290222\|ref\|YP_003055970.1\| 3-methyl-adenine DNA glycosylase I, constitutive [Escherichia coli ... gi\|254163472, gi... - gi\|254163472\|ref\|YP_003046580.1\| 3-methyl-adenine DNA glycosylase I, constitutive [Escherichia coli ... gi\|23200339\|pdb\|... - Chain A, Solution Structure Of 3-Methyladenine Dna Glycosylase I (Tag)	318.0	[0..1]	[187..1]
gi\|13363908, gi\|... - gi\|15833688\|ref\|NP_312461.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli O157:H7], gi\|13363... gi\|209755270, gi... - pir\|\|F86029 3-methyladenine DNA glycosylase I [imported] - Escherichia coli (strain O157:H7, substra... gi\|15804095, gi\|... - gi\|15804095\|ref\|NP_290134.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli O157:H7 EDL933], g... gi\|189369511, gi... - gi\|189369511\|gb\|EDU87927.1\| DNA-3-methyladenine glycosylase I [Escherichia coli O157:H7 str. EC4501]... gi\|13363908, gi\|... - gi\|15833688\|ref\|NP_312461.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli O157:H7 str. Sakai... gi\|168785419, gi... - gi\|189374584\|gb\|EDU93000.1\| DNA-3-methyladenine glycosylase I [Escherichia coli O157:H7 str. EC869],... gi\|217322730, gi... - gi\|217326509\|ref\|ZP_03442593.1\| DNA-3-methyladenine glycosylase I [Escherichia coli O157:H7 str. TW1...	318.0	[0..1]	[187..1]
gi\|187428988, gi... - gi\|75179801\|ref\|ZP_00699788.1\| COG2818: 3-methyladenine DNA glycosylase [Shigella boydii BS512], gi\|...	318.0	[0..1]	[187..1]
gi\|81243533, gi\|... - gi\|82779385\|ref\|YP_405734.1\| 3-methyl-adenine DNA glycosylase I [Shigella dysenteriae Sd197], gi\|812...	318.0	[0..1]	[187..1]
gi\|75197457, gi\|... - gi\|75197457\|ref\|ZP_00707527.1\| COG2818: 3-methyladenine DNA glycosylase [Escherichia coli HS], gi\|15... gi\|157158800, gi... - gi\|75188314\|ref\|ZP_00701581.1\| COG2818: 3-methyladenine DNA glycosylase [Escherichia coli E24377A], ... gi\|124499886, gi... - gi\|124529428\|ref\|ZP_01700432.1\| DNA-3-methyladenine glycosylase I [Escherichia coli B], gi\|124499886... gi\|73857676, gi\|... - gi\|74314199\|ref\|YP_312618.1\| 3-methyl-adenine DNA glycosylase I [Shigella sonnei Ss046], gi\|73857676... gi\|218556109, gi... - gi\|218556109\|ref\|YP_002389022.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli IAI1], gi\|2183... gi\|193061685, gi... - gi\|75260161\|ref\|ZP_00731429.1\| COG2818: 3-methyladenine DNA glycosylase [Escherichia coli E22], gi\|1... gi\|218353998, gi... - gi\|218697266\|ref\|YP_002404933.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli 55989], gi\|218... gi\|192958194, gi... - gi\|75237487\|ref\|ZP_00721520.1\| COG2818: 3-methyladenine DNA glycosylase [Escherichia coli E110019], ... gi\|169753150, gi... - gi\|170018222\|ref\|YP_001723176.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli ATCC 8739], gi... gi\|191165338, gi... - gi\|75231605\|ref\|ZP_00717963.1\| COG2818: 3-methyladenine DNA glycosylase [Escherichia coli B7A], gi\|1... gi\|209914272, gi... - gi\|209921013\|ref\|YP_002295097.1\| 3-methyl-adenine DNA glycosylase I [Escherichia coli SE11], gi\|2099...	318.0	[0..1]	[187..1]

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Predicted Domain #1

Region A:
Residues: [1-187]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERCGWVSQD PLYIAYHDNE WGVPETDSKK LFEMICLEGQ QAGLSWITVL KKRENYRACF  60
   61 HQFDPVKVAA MQEEDVERLV QDAGIIRHRG KIQAIIGNAR AYLQMEQNGE PFVDFVWSFV 120
  121 NHQPQVTQAT TLSEIPTSTS ASDALSKALK KRGFKFVGTT ICYSFMQACG LVNDHVVGCC 180
  181 CYPGNKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.39794
Match:	1lmzA
Description:	3-Methyladenine DNA glycosylase I (Tag)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	4.08559331236111	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	3.73234184319832	bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity	3.12421941323765	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.54759386266723	bayes_pls_golite062009
catalytic activity	2.50389926428623	bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity	1.80199518353554	bayes_pls_golite062009
alkylbase DNA N-glycosylase activity	1.75218522602775	bayes_pls_golite062009
hydrolase activity	1.39000450534744	bayes_pls_golite062009
DNA-3-methyladenine glycosylase I activity	1.14337995879633	bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity	0.473206156100251	bayes_pls_golite062009
uracil DNA N-glycosylase activity	0.29478804124408	bayes_pls_golite062009
oxidized pyrimidine base lesion DNA N-glycosylase activity	0.253198605718519	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: